公开(公告)号：US06299907B1

公开(公告)日：2001-10-09

申请号：US09096990

申请日：1998-06-12

Applicant: Paul A. Seib ,  Kyungsoo Woo

Inventor： Paul A. Seib ,  Kyungsoo Woo

IPC: A61K950

CPC classification number: A61K8/732 ,  A21D2/186 ,  A23L29/219 ,  A61K8/0279 ,  A61K2800/654 ,  A61Q5/02 ,  A61Q19/00 ,  C08B30/12 ,  C08B31/003

Abstract: Reversible swellable modified starch products are provided in the form of individual, chemically cross-linked starch granules capable of undergoing multiple hot or cold water swelling/drying cycles without losing the individuality of the starch granules, and with essentially no loss of starch solubles. The starches are prepared by forming a dispersion of starch granules in water, with the granules undergoing swelling and having a crystalline phase; a cross-linker (preferably a phosphorylating agent) is added to the dispersion in order to cross-link the starch under conditions to avoid complete gelatinization thereof. The swollen/cross-linked starch granules are then heated in excess water in order to melt the crystalline phase of the granules. The granules exhibit a network-like structure with internal voids.

Abstract translation: 可逆膨胀改性淀粉产品以能够经历多次热或冷水溶胀/干燥循环的单独的化学交联的淀粉颗粒的形式提供，而不损失淀粉颗粒的个性，并且基本上没有淀粉可溶物的损失。 淀粉通过在水中形成淀粉颗粒的分散体制备，颗粒经历膨胀并具有结晶相; 将交联剂（优选磷酸化剂）加入到分散体中，以便在条件下交联淀粉以避免其完全凝胶化。 然后将膨胀/交联的淀粉颗粒在过量的水中加热，以熔化颗粒的结晶相。 颗粒表现出具有内部空隙的网状结构。

公开(公告)号：US5855946A

公开(公告)日：1999-01-05

申请号：US870955

申请日：1997-06-06

Applicant: Paul A. Seib ,  Kyungsoo Woo

Inventor： Paul A. Seib ,  Kyungsoo Woo

IPC: A23L1/308 ,  A21D2/10 ,  A21D2/18 ,  A23L1/05 ,  A23L1/0522 ,  A23L1/10 ,  C08B31/00 ,  C08B31/06 ,  A21D13/00

CPC classification number: C08B31/003 ,  A21D2/186 ,  A23L29/219 ,  C08B31/066

Abstract: Chemically modified RS.sub.4 starches are provided which have a high degree of resistance to .alpha.-amylase digestion and can serve as low calorie food additives in products such as breads or crackers as a source of dietary fiber. The starches of the invention can be prepared from any type of starting starch (e.g., wheat, corn, oat, rice, tapioca, mung bean, potato or high amylose starches) and are preferably formed as phosphorylated distarch phosphodiesters. The preferred phosphorylating agent is a mixture of sodium trimetaphosphate (STMP) and sodium tripolyphosphate (STPP) in the presence of sodium chloride or sulfate. The starches are advantageously prepared in an aqueous slurry reaction at basic pH and moderate heating.

Abstract translation: 提供化学修饰的RS4淀粉，其对α-淀粉酶消化具有高度抗性，并且可以作为膳食纤维来源的诸如面包或饼干的产品中的低热量食品添加剂。 本发明的淀粉可以由任何类型的起始淀粉（例如小麦，玉米，燕麦，米，木薯，绿豆，马铃薯或高直链淀粉）制备，并且优选以磷酸化的二磷酸二酯形成。 优选的磷酸化剂是氯化钠或硫酸盐存在下的三偏磷酸钠（STMP）和三聚磷酸钠（STPP）的混合物。 淀粉有利地在碱性pH和适度加热下以水性浆料反应制备。

公开(公告)号：US4647672A

公开(公告)日：1987-03-03

申请号：US749081

申请日：1985-06-25

Applicant: Paul A. Seib ,  Ming-Long Liao

Inventor： Paul A. Seib ,  Ming-Long Liao

IPC: A23L33/15 ,  A61K31/665 ,  A61P3/02 ,  C07D307/62 ,  C07F9/09 ,  C07F9/655

CPC classification number: C07F9/65515

Abstract: A new stable derivative of ascorbic acid, ascorbate 2-polyphosphate, is disclosed, together with a high-yield method of synthesis thereof. The method preferably includes steps of reacting an ascorbic acid such as L-ascorbic acid or a derivative thereof such as 5,6-O-isopropylidene-L-ascorbic acid with salts of metaphosphoric acid in an aqueous system and in the presence of sufficient base to maintain the pH of the reaction mixture at a level of at least above 9 to obtain 2-polyphosphorylation of the ascorbic acid. In particularly preferred forms, 1 M L-ascorbic acid is reacted in water with 1.5-3 equivalent of sodium or potassium trimetaphosphate at a temperature of 25.degree.-55.degree. C., and an alkali metal hydroxide such as potassium hydroxide is intermittently added to the reaction mixture as needed over a 1-10 hr. reaction period to maintain the pH thereof at a level of about 10.5-12 during the entire reaction. After neutralization the reaction mixture contains no noxious or toxic materials, and the entire mixture may be added to food or feed. Pure salts of ascorbate 2-triphosphate can be isolated readily using conventional chromatographic techniques. It has also been found that the compounds of the invention are more difficult to oxidize, and release ascorbic acid and are more slowly hydrolyzed than the monophosphate derivative of ascorbic acid.

Abstract translation: 公开了抗坏血酸，2-多磷酸抗坏血酸的新的稳定的衍生物，以及高产率的合成方法。 所述方法优选包括以下步骤：使水溶性体系中的抗坏血酸例如L-抗坏血酸或其衍生物如5,6-O-异亚丙基-L-抗坏血酸与偏磷酸盐反应，并在足够的碱 以将反应混合物的pH保持在至少高于9的水平以获得抗坏血酸的2-多磷酸化。 在特别优选的形式中，在25-55℃的温度下，1M水溶性抗坏血酸与1.5-3当量的三偏磷酸钠或钾反应，间歇地向碱金属氢氧化物如氢氧化钾中加入 在1-10小时内根据需要反应混合物。 在整个反应期间将pH保持在约10.5-12的水平。 中和后，反应混合物不含有毒或有毒物质，整个混合物可加入食品或饲料中。 使用常规色谱技术可以容易地分离出抗坏血酸盐2-三磷酸盐的纯盐。 还发现本发明的化合物比抗坏血酸的单磷酸酯衍生物更难氧化，释放出抗坏血酸，并且比水解的更缓慢。

公开(公告)号：US5248702A

公开(公告)日：1993-09-28

申请号：US933207

申请日：1992-08-21

Applicant: Paul E. Neumann ,  Paul A. Seib

Inventor： Paul E. Neumann ,  Paul A. Seib

IPC: B65D65/46 ,  B65D81/09 ,  C08L3/02 ,  C08L71/02

CPC classification number: B65D81/09 ,  B65D65/466 ,  C08L3/02 ,  C08L2201/06 ,  C08L71/02 ,  Y02W90/11 ,  Y02W90/13 ,  Y10S521/916

Abstract: Starch-based biodegradable packaging fillers are provided which have high volumes, low weights, and excellent compressibility and resiliency properties. The products of the invention are fabricated by extrusion of a starch substrate, most preferably normal wheat starch, in the presence of minor amounts of a polyalkylene glycol or derivative thereof and/or a particulate bubble-nucleating agent. Effective biodegradable packaging fillers can thus be fabricated without the use of expensive modified starch substrates; however, such substrates can also be employed if desired, and the additives of the invention improve these products as well. In preferred production procedures, the additives are mixed with the starch substrate, and the mixture is preconditioned and then extruded through a twin screw extruder.

公开(公告)号：US5185382A

公开(公告)日：1993-02-09

申请号：US932938

申请日：1992-08-21

Applicant: Paul E. Neumann ,  Paul A. Seib

Inventor： Paul E. Neumann ,  Paul A. Seib

IPC: B29C47/40 ,  B29C47/64 ,  B65D65/46 ,  B65D81/09 ,  C08J9/00 ,  C08J9/12 ,  C08L3/00 ,  C08L71/02

CPC classification number: C08J9/0061 ,  B29C47/40 ,  B29C47/64 ,  B65D65/466 ,  B65D81/09 ,  C08J9/125 ,  C08L3/00 ,  B29C47/0009 ,  C08J2303/00 ,  C08J2471/00 ,  C08L2201/06 ,  C08L71/02 ,  Y02W90/11 ,  Y02W90/13

Abstract: Starch-based biodegradable packaging fillers are provided which have high volumes, low weights, and excellent compressibility and resiliency properties. The products of the invention are fabricted by extrusion of a starch substrate, most preferably normal wheat starch, in the presence of minor amounts of a polyalkylene glycol or derivative thereof and/or a particulate bubble-nucleating agent. Effective biodegradable packaging fillers can thus be fabricated without the use of expensive modified starch substrates; however, such substrates can also be employed if desired, and the additives of the invention improve these products as well. In preferred production procedures, the additives are mixed with the starch substrate, and the mixture is preconditioned and then extruded through a twin screw extruder.

Abstract translation: 提供基于淀粉的可生物降解的包装填料，其具有高体积，低重量和优异的可压缩性和弹性性能。 本发明的产品通过在少量聚亚烷基二醇或其衍生物和/或颗粒状气泡成核剂的存在下挤出淀粉底物，最优选常规小麦淀粉来制造。 因此可以在不使用昂贵的改性淀粉基质的情况下制造有效的可生物降解的包装填料; 然而，如果需要也可以使用这样的基材，并且本发明的添加剂也改进这些产品。 在优选的生产方法中，将添加剂与淀粉基质混合，并将混合物预处理，然后通过双螺杆挤出机挤出。

公开(公告)号：US5057157A

公开(公告)日：1991-10-15

申请号：US600910

申请日：1990-10-22

Applicant: Jay-lin Jane ,  Paul A. Seib

Inventor： Jay-lin Jane ,  Paul A. Seib

IPC: C08B30/14

CPC classification number: C08B30/14

Abstract: A process for the preparation of granular cold water swelling/soluble starches by alcoholic-alkali treatments is disclosed which comprises contacting a quantity of starch granules with respective quantities of an alcohol and a strong base to swell the granules and convert the starch to form having increased cold water solubility. The process can be used on waxy, high amylose, tuber, and normal starches. The resulting cold water swelling/soluble starch preferably exhibits about 50% to 94% solubility in cold water.

Abstract translation: 公开了一种通过酒精 - 碱处理制备颗粒状冷水膨胀/可溶性淀粉的方法，其包括使一定数量的淀粉颗粒与相应量的醇和强碱接触以使颗粒溶胀并将淀粉转化成具有增加的 冷水溶解度。 该方法可用于蜡质，高直链淀粉，块茎和正常淀粉。 所得的冷水溶胀/可溶性淀粉优选在冷水中表现出约50％至94％的溶解度。

公开(公告)号：US4975293A

公开(公告)日：1990-12-04

申请号：US141857

申请日：1988-01-11

Applicant: Kevin B. Hicks ,  Gerald M. Sapers ,  Paul A. Seib

Inventor： Kevin B. Hicks ,  Gerald M. Sapers ,  Paul A. Seib

IPC: A23B7/154 ,  A23B7/155 ,  A23B7/16 ,  A23L2/42 ,  A23L2/44 ,  A23L2/80

CPC classification number: A23L2/44 ,  A23B7/154 ,  A23B7/155 ,  A23B7/16 ,  A23L2/42 ,  A23L2/80

Abstract: A process of inhibiting enzymatic browning in raw fruit and vegetable juices comprising treating the juices with cyclodextrins, individually or in combination. Soluble cyclodextrins treatments may be added directly to the juices. In the alternative, isoluble cyclodextrins may be used as a packing in a column or in a batch treatment process. In effect, treatments of the invention tend to limit the extent or rate of enzymatic browning in the affected juices. Also disclosed are novel browning inhibiting compositions which are effective in controlling enzymatic browning in raw fruit and vegetable juices. The novel compositions are potential alternatives for presently used sulfites.

Abstract translation: 抑制生水果和蔬菜汁中的酶促褐变的方法，包括单独或组合地用环糊精处理果汁。 可溶性环糊精处理可以直接添加到果汁中。 在替代方案中，可将不溶性环糊精用作柱中的填料或间歇处理工艺。 实际上，本发明的处理倾向于限制受影响的果汁中酶促褐变的程度或速率。 还公开了新鲜的抑制褐变的组合物，其有效地控制生水果和蔬菜汁中的酶促褐变。 新型组合物是目前使用的亚硫酸盐的潜在替代物。

公开(公告)号：US4044154A

公开(公告)日：1977-08-23

申请号：US632353

申请日：1975-11-17

Applicant: Russell C. Hoseney ,  Paul A. Seib ,  Charles W. Deyoe

Inventor： Russell C. Hoseney ,  Paul A. Seib ,  Charles W. Deyoe

IPC: A21D2/14

CPC classification number: A21D2/14

Abstract: Salts of ascorbic acid 6-acylates (both the D-isoascorbic and L-ascorbic isomers) are provided which have significant utility as multi-functional, easily dispersible additives for yeast-leavened doughs or batters and serve as biologically active sources of vitamin C even when added to the dough or batter during preparation thereof and subjected to baking or frying temperatures. The additives hereof are also functional as dough conditioners, anti-staling agents, and shortening sparing agents, and also serve to maintain or even enhance loaf volume in resultant breads and the like and permit incorporation of protein supplements such as soy flour into such products without deleteriously affecting desirable organoleptic properties thereof. The 6-O-acyl ascorbate salts of the invention are compounds of the formula ##STR1## wherein M and Q are different and respectively taken fom the group consisting of --H and --OH, R represents an aliphatic group having from 12 to 18 carbon atoms, inclusive, and X is a salt-forming member selected from the group consisting of sodium, potassium, calcium and magnesium. A method of synthesizing the above acyl ester salts is also provided which includes the step of reacting the free acid form of the ester with a stoichiometric quantity of a base taken from the group consisting of the sodium, potassium, calcium and magnesium compounds of (1) an acid that is a weaker acid than the ester, and (2) an acid which can be removed from the reaction mixture by volatilization. The reaction is carried out in a compatible solvent which dissolves the ester and the reacting base or salt and does not hinder the desired reaction.

Abstract translation: 提供抗坏血酸6-酰化物的盐（D-异抗坏血酸和L-抗坏血酸异构体），其具有作为酵母发酵面团或面糊的多功能，易分散的添加剂的显着效用，并且作为维生素C的生物活性来源甚至 当在其制备期间加入面团或面糊并经受烘烤或油炸温度。 其添加剂也可用作面团调理剂，防老化剂和起酥油保鲜剂，并且还用于维持或甚至增加所得面包等中的面包体积，并允许将蛋白质补充剂如大豆粉加入到这样的产品中而没有 有害地影响其所需的感官特性。 本发明的6-O-酰基抗坏血酸盐是下式的化合物，其中M和Q不同，分别取自-H和-OH组成的组，R表示具有12至18个碳原子的脂族基团 原子，X是选自钠，钾，钙和镁的成盐剂。 还提供了合成上述酰基酯盐的方法，该方法包括使游离酸形式的酯与化学计量的碱取自（1）的钠，钾，钙和镁化合物的碱的步骤 ）酸比酸弱的酸，和（2）可以通过挥发从反应混合物中除去的酸。 反应在溶解酯和反应碱或盐的相容溶剂中进行，并且不妨碍所需的反应。

公开(公告)号：US5208267A

公开(公告)日：1993-05-04

申请号：US822885

申请日：1992-01-21

Applicant: Paul E. Neumann ,  Paul A. Seib

Inventor： Paul E. Neumann ,  Paul A. Seib

IPC: B65D65/46 ,  B65D81/09 ,  C08L3/02 ,  C08L71/02

CPC classification number: B65D81/09 ,  B65D65/466 ,  C08L3/02 ,  C08L2201/06 ,  C08L71/02 ,  Y02W90/11 ,  Y02W90/13

Abstract: Starch-based biodegradable packaging fillers are provided which have high volumes, low weights, and excellent compressibility and resiliency properties. The products of the invention are fabricated by extrusion of a starch substrate, most preferably normal wheat starch, in the presence of minor amounts of a polyalkylene glycol or derivative thereof and/or a particulate bubble-nucleating agent. Effective biodegradable packaging fillers can thus be fabricated without the use of expensive modified starch substrates; however, such substrates can also be employed if desired, and the additives of the invention improve these products as well. In preferred production procedures, the additives are mixed with the starch substrate, and the mixture is preconditioned and then extruded through a twin screw extruder.

Abstract translation: 提供基于淀粉的可生物降解的包装填料，其具有高体积，低重量和优异的可压缩性和弹性性能。 本发明的产品通过在少量聚亚烷基二醇或其衍生物和/或颗粒气泡成核剂的存在下挤出淀粉底物，最优选常规小麦淀粉来制备。 因此可以在不使用昂贵的改性淀粉基质的情况下制造有效的可生物降解的包装填料; 然而，如果需要也可以使用这样的基材，并且本发明的添加剂也改进这些产品。 在优选的生产方法中，将添加剂与淀粉基质混合，并将混合物预处理，然后通过双螺杆挤出机挤出。

公开(公告)号：US5110950A

公开(公告)日：1992-05-05

申请号：US713791

申请日：1991-06-12

Applicant: Paul A. Seib ,  Xiao Y. Wang

Inventor： Paul A. Seib ,  Xiao Y. Wang

IPC: C07F9/655

CPC classification number: C07F9/65515

Abstract: A catalyzed synthesis of ascorbate 2-phosphorylated compounds is provided which gives both mono-and polyphosphorylated species in excellent yield using inexpensive, readily available reactants. The method involves forming a reaction mixture of an ascorbic acid reactant such as L-ascorbic acid and a metaphosphate phosphorylating agent (e.g., sodium trimetaphosphate), and carrying out the phosphorylation reaction in the presence of a catalyzing ion selected from the group consisiting of calcium, strontium and barium ion and mixtures thereof, while maintaining the pH of the reaction mixture at a level of from about 3-12. The synthesis is characterized by very short reaction times, preferably from about 15 minutes-2 hours, and moderate temperatures on the order of 18.degree. C.-25.degree. C. Preferably, the catalyzing ion is provided by addition of calcium, strontium or barium hydroxide to the reaction mixture, this serving to also elevate the pH of the system to the desired range.

Abstract translation: 提供了抗坏血酸2-磷酸化化合物的催化合成，其使用廉价的容易获得的反应物使得单磷酸化和多磷酸化物质具有优异的产率。 该方法包括形成抗坏血酸反应物如L-抗坏血酸和偏磷酸磷酸化剂（例如三偏磷酸钠）的反应混合物，并在催化离子存在下进行磷酸化反应，所述催化离子选自钙 ，锶和钡离子及其混合物，同时将反应混合物的pH保持在约3-12的水平。 合成的特征在于非常短的反应时间，优选约15分钟-2小时，以及约18℃-25℃的中等温度。优选地，通过加入钙，锶或钡来提供催化离子 氢氧化物反应混合物，这也用于将系统的pH提升到所需的范围。