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1.发明申请ENDOLUMINAL IMPLANTABLE SURFACES, STENTS, AND GRAFTS AND METHOD OF MAKING THE SAME 审中-公开内膜可植入性表面，手术和手术及其制造方法公开(公告)号：US20140332499A1
公开(公告)日：2014-11-13
申请号：US14276741
申请日：2014-05-13
Applicant: PALMAZ SCIENTIFIC, INC.
Inventor： Julio C. Palmaz , Armando Garza
CPC classification number: A61F2/07 , A61F2/0077 , A61F2/91 , A61F2002/0081 , A61F2002/9522 , A61F2210/0076 , A61F2240/001 , B23K26/0624 , B23K26/146 , B23K26/355 , B23K26/364 , B29C2035/0838 , C23F4/00
Abstract: A method of manufacturing an endoluminal implantable surface, stent, or graft includes the steps of providing an endoluminal implantable surface, stent, or graft having an inner wall surface, an outer wall surface, and a wall thickness and forming a pattern design into the endoluminal implantable surface, stent, or graft. At least one groove is created in the inner surface of the intravascular stent by applying a laser machining method to the inner surface.
Abstract translation: 制造内腔可植入表面，支架或移植物的方法包括以下步骤：提供具有内壁表面，外壁表面和壁厚的腔内可植入表面，支架或移植物，并将模式设计形成到腔内 植入式表面，支架或移植物。 通过对内表面施加激光加工方法，在血管内支架的内表面中形成至少一个凹槽。
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2.发明申请IMPLANTABLE MEDICAL DEVICE HAVING ENHANCED ENDOTHELIAL MIGRATION FEATURES AND METHODS OF MAKING THE SAME 有权具有增强的内切移植特征的可植入医疗装置及其制造方法公开(公告)号：US20140194974A1
公开(公告)日：2014-07-10
申请号：US14156017
申请日：2014-01-15
Applicant: Palmaz Scientific, Inc.
Inventor： Julio C. Palmaz
IPC: A61F2/82
CPC classification number: A61F2/0077 , A61F2/01 , A61F2/06 , A61F2/24 , A61F2/82 , A61F2/86 , A61F2/90 , A61F2/91 , A61F2230/0017 , A61F2230/0026 , A61F2230/0056 , A61F2240/001 , A61F2250/0051 , Y10T29/49 , Y10T29/49826
Abstract: An implantable medical device having enhanced endothelial migration features, generally comprises: a structural member including a leading edge and a trailing edge interconnected by a third surface region, the leading edge including a second surface region in a generally curvilinear cross-section, and the trailing edge including a fourth surface region in a generally curvilinear cross-section, whereby blood flow over the second surface region generate shear stress at the second surface region without an eddy region in the second surface region.
Abstract translation: 具有增强的内皮迁移特征的可植入医疗装置通常包括：包括由第三表面区域相互连接的前缘和后缘的结构构件，前缘包括大致曲线横截面的第二表面区域， 边缘，其包括大致曲线横截面中的第四表面区域，由此第二表面区域上的血流在第二表面区域处产生剪切应力，而在第二表面区域中没有涡流区域。
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3.发明申请公开(公告)号：US20170028109A1
公开(公告)日：2017-02-02
申请号：US15057986
申请日：2016-03-01
Applicant: PALMAZ SCIENTIFIC, INC.
Inventor： Julio C. Palmaz
CPC classification number: A61L31/16 , A61F2/0077 , A61F2/02 , A61L2400/18 , C23C14/042 , C23C14/24 , C23C14/5873 , G03F7/20
Abstract: An implantable biocompatible material includes one or more vacuum deposited layers of biocompatible materials deposited upon a biocompatible base material. At least a top most vacuum deposited layer includes a homogeneous molecular pattern of distribution along the surface thereof and comprises a patterned array of geometric physiologically functional features.
Abstract translation: 可植入生物相容性材料包括沉积在生物相容性基材上的生物相容性材料的一个或多个真空沉积层。 至少最顶层的真空沉积层包括沿其表面分布的均匀分子图案，并且包括几何生理功能特征的图案化阵列。
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4.发明授权公开(公告)号：US09050394B2
公开(公告)日：2015-06-09
申请号：US13654923
申请日：2012-10-18
Applicant: Palmaz Scientific, Inc.
Inventor： Scott P. Carpenter , Armando Garza , Julio C. Palmaz
CPC classification number: A61L31/022 , A61F2/0077 , A61F2/2418 , A61F2/30771 , A61F2/36 , A61F2/915 , A61F2002/0081 , A61F2002/30029 , A61F2002/3083 , A61F2002/30838 , A61F2002/30925 , A61F2240/00 , A61F2240/001 , A61L31/14 , A61L2400/18 , Y10T29/49982
Abstract: The invention relates to methods and apparatus for manufacturing medical devices wherein the medical device has a surface treated to promote the migration of cells onto the surface of the medical device. In particular, the surface of the medical device has at least one topographical feature formed therein.
Abstract translation: 本发明涉及用于制造医疗装置的方法和装置，其中医疗装置具有被处理以促进细胞迁移到医疗装置表面上的表面。 特别地，医疗装置的表面具有形成在其中的至少一个形貌特征。
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5.发明申请TOPOGRAPHICAL FEATURES AND PATTERNS ON A SURFACE OF A MEDICAL DEVICE AND METHODS OF MAKING THE SAME 审中-公开医疗器械表面的地形特征及图案及其制作方法公开(公告)号：US20140114435A1
公开(公告)日：2014-04-24
申请号：US13801173
申请日：2013-03-13
Applicant: Palmaz Scientific, Inc.
Inventor： Scott Carpenter , Michael Poor , Julio C. Palmaz
IPC: A61F2/00
CPC classification number: A61F2/0077 , A61F2/24 , A61F2/82 , A61F2/915 , A61F2002/0081 , Y10T29/49982
Abstract: The invention relates to medical devices that has a surface configured to promote the migration of cells onto the surface of the medical device. In particular, the surface of the medical device has a noncontiguous pattern of topographical features formed therein or thereon.
Abstract translation: 本发明涉及具有被配置为促进细胞迁移到医疗装置的表面上的表面的医疗装置。 特别地，医疗装置的表面具有在其中或其上形成的不连续的形貌特征。
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Patent Agency Ranking
公开(公告)号：US20130131784A1
公开(公告)日：2013-05-23
申请号：US13673168
申请日：2012-11-09
Applicant: Advanced Bio Prosthetic Surfaces, Ltd., a wholly owned subsidiary of Palmaz Scientific, Inc.
Inventor： Christopher E. Banas , Julio C. Palmaz
IPC: A61F2/04
CPC classification number: A61F2/04 , A61F2/06 , A61F2/82 , A61L27/06 , A61L27/50 , A61L31/022 , A61L31/14 , C23C14/0005 , Y10T83/04
Abstract: Implantable medical grafts fabricated of metallic or pseudometallic films of biocompatible materials having a plurality of microperforations passing through the film in a pattern that imparts fabric-like qualities to the graft or permits the geometric deformation of the graft. The implantable graft is preferably fabricated by vacuum deposition of metallic and/or pseudometallic materials into either single or multi-layered structures with the plurality of microperforations either being formed during deposition or after deposition by selective removal of sections of the deposited film. The implantable medical grafts are suitable for use as endoluminal or surgical grafts and may be used as vascular grafts, stent-grafts, skin grafts, shunts, bone grafts, surgical patches, non-vascular conduits, valvular leaflets, filters, occlusion membranes, artificial sphincters, tendons and ligaments.
Abstract translation: 可植入的医用移植物由生物相容性材料的金属或假金属膜制成，具有多个微孔穿过膜，该图案赋予移植物类织物质量或允许移植物的几何变形。 可植入移植物优选通过将金属和/或假金属材料真空沉积成单层或多层结构而制成，其中多个微穿孔在沉积期间或沉积后通过选择性去除沉积膜的部分而形成。 可植入的医用移植物适合用作腔内或手术移植物，可用作血管移植物，支架移植物，皮肤移植物，分流器，骨移植物，外科补片，非血管导管，瓣膜小叶，滤器，闭塞膜，人造 括约肌，肌腱和韧带。
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公开(公告)号：US09566633B2
公开(公告)日：2017-02-14
申请号：US13678335
申请日：2012-11-15
Applicant: Palmaz Scientific, Inc.
Inventor： Armando Garza , Julio C. Palmaz
CPC classification number: A61F2/915 , A61F2/91 , A61F2210/0076 , A61F2230/0054 , A61F2240/001 , B21D51/16 , B23K26/36 , B23K2101/06
Abstract: An intravascular stent having a hybrid pattern. The hybrid pattern comprises a plurality of circumferentially self-expansible members comprising a plurality of interconnected, geometrically deformable closed cells, adjacent self-expansible members interconnected by a plurality of bridge members linking a first interconnection between two closed cells in a first self-expansible member to a second interconnection between two closed cells in a second self-expansible member, wherein the second interconnection is circumferentially offset and non-adjacent to the first interconnection.
Abstract translation: 具有混合型式的血管内支架。 混合图案包括多个周向自膨胀构件，其包括多个互连的几何可变形闭孔，相邻的可自膨胀构件通过多个桥构件互连，所述多个桥构件将第一自膨胀构件中的两个闭孔之间的第一互连 到第二自扩张构件中的两个闭孔之间的第二互连，其中所述第二互连沿周向偏移并且不与所述第一互连相邻。
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8.发明申请公开(公告)号：US20140294910A1
公开(公告)日：2014-10-02
申请号：US14219924
申请日：2014-03-19
Applicant: PALMAZ SCIENTIFIC, INC.
Inventor： Julio C. Palmaz
IPC: A61L31/16
CPC classification number: A61L31/16 , A61F2/0077 , A61F2/02 , A61L2400/18 , C23C14/042 , C23C14/24 , C23C14/5873 , G03F7/20
Abstract: An implantable biocompatible material includes one or more vacuum deposited layers of biocompatible materials deposited upon a biocompatible base material. At least a top most vacuum deposited layer includes a homogeneous molecular pattern of distribution along the surface thereof and comprises a patterned array of geometric physiologically functional features.
Abstract translation: 可植入生物相容性材料包括沉积在生物相容性基材上的生物相容性材料的一个或多个真空沉积层。 至少最顶层的真空沉积层包括沿其表面分布的均匀分子图案，并且包括几何生理功能特征的图案化阵列。
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公开(公告)号：US20130334032A1
公开(公告)日：2013-12-19
申请号：US13908933
申请日：2013-06-03
Applicant: Advanced Bio Prosthetic Surfaces, Ltd. a wholly owned subsidiary of Palmaz Scientific, Inc.
Inventor： Julio C. Palmaz , Christopher T. Boyle
IPC: C23C14/35
CPC classification number: C23C14/35 , A61F2/0077 , A61F2/06 , A61F2/91 , A61F2/915 , A61F2002/91533 , A61F2002/9155 , A61F2002/91558 , A61F2210/0076 , A61F2240/001 , Y10T29/49812 , Y10T29/49885 , Y10T29/4998 , Y10T29/49982 , Y10T29/49995
Abstract: Implantable medical grafts fabricated of metallic or pseudometallic films of biocompatible materials having a plurality of microperforations passing through the film in a pattern that imparts fabric-like qualities to the graft or permits the geometric deformation of the graft. The implantable graft is preferably fabricated by vacuum deposition of metallic and/or pseudometallic materials into either single or multi-layered structures with the plurality of microperforations either being formed during deposition or after deposition by selective removal of sections of the deposited film. The implantable medical grafts are suitable for use as endoluminal or surgical grafts and may be used as vascular grafts, stent-grafts, skin grafts, shunts, bone grafts, surgical patches, non-vascular conduits, valvular leaflets, filters, occlusion membranes, artificial sphincters, tendons and ligaments.
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10.发明授权公开(公告)号：US11045297B2
公开(公告)日：2021-06-29
申请号：US13801173
申请日：2013-03-13
Applicant: Palmaz Scientific, Inc.
Inventor： Scott Carpenter , Michael Poor , Julio C. Palmaz
Abstract: The invention relates to medical devices that has a surface configured to promote the migration of cells onto the surface of the medical device. In particular, the surface of the medical device has a noncontiguous pattern of topographical features formed therein or thereon.
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