公开(公告)号：US20180169653A1

公开(公告)日：2018-06-21

申请号：US15899982

申请日：2018-02-20

申请人： PANASONIC CORPORATION ,  IMEC VZW

发明人： Shuji SATO ,  Yasuaki OKUMURA ,  Yukari NISHIYAMA ,  Tatsurou KAWAMURA ,  Ben JONES ,  Liesbet LAGAE ,  Tim STAKENBORG

IPC分类号： B01L3/00 ,  G01N33/543

CPC分类号： B01L3/502707 ,  B01L3/502715 ,  B01L3/50273 ,  B01L3/502746 ,  B01L2300/041 ,  B01L2300/0809 ,  B01L2300/0816 ,  B01L2300/0851 ,  B01L2300/0861 ,  B01L2400/0406 ,  B01L2400/0688 ,  G01N21/03 ,  G01N27/416 ,  G01N33/54386

摘要： A micro analysis chip comprises an inlet and a fluid flow path communicating thereto. The fluid flow path comprises a first flow path, a second flow path, and a third flow path arranged continuously along a longitudinal direction of the fluid flow path. An antibody is bound on at least one peripheral surface selected from the group consisting of peripheral surfaces of the second and third flow paths. A cross-sectional area of the third flow path is constant or increased monotonically along a direction X from the second flow path toward the third flow path. A cross-sectional area of the second flow path is increased monotonically along the direction X from the one end to the other end of the second flow path. A cross-sectional area of the first flow path is larger than a cross-sectional area at the one end of the second flow path.

公开(公告)号：US20160073938A1

公开(公告)日：2016-03-17

申请号：US14951301

申请日：2015-11-24

申请人： PANASONIC CORPORATION

发明人： Yasuaki OKUMURA ,  Tatsurou KAWAMURA ,  Masaru MINAMIGUCHI ,  Masahiko SHIOI

IPC分类号： A61B5/1459 ,  G01N21/65

CPC分类号： A61B5/1459 ,  A61B5/0075 ,  A61B5/14532 ,  G01N21/554 ,  G01N21/658

摘要： An exemplary sensor chip includes a substrate, a metal pattern, a proximate substance, and a light shielding layer. The metal pattern is on the substrate. The proximate substance is on or near the metal pattern. The light shielding layer is provided on the substrate so as to cover the metal pattern and the proximate substance. The light shielding layer is a layer that blocks the excitation light from going into the proximate substance, and is made of a substance which becomes degraded inside a subject.

摘要翻译： 示例性传感器芯片包括基板，金属图案，近似物质和遮光层。 金属图案在基板上。 邻近物质在金属图案上或附近。 遮光层设置在基板上以覆盖金属图案和近似物质。 遮光层是阻止激发光进入邻近物质的层，并且由在被检体内变质的物质构成。

公开(公告)号：US20150233836A1

公开(公告)日：2015-08-20

申请号：US14705343

申请日：2015-05-06

申请人： PANASONIC CORPORATION

发明人： Yasuaki OKUMURA ,  Tatsurou KAWAMURA ,  Masahiko SHIOI ,  Masaru MINAMIGUCHI

IPC分类号： G01N21/65

CPC分类号： G01N21/658 ,  A61B5/0075 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/1455 ,  A61B5/1459 ,  G01N2201/06113 ,  G01N2201/068 ,  G01N2201/12

摘要： An exemplary sensor chip includes a substrate, a metal pattern formed on a side of the substrate that is irradiated with excitation light, and a first substance and a second substance provided near the metal pattern. A first intensity Xa of the first surface-enhanced Raman-scattered light from the first substance and a second intensity Xb of the second surface-enhanced Raman-scattered light from the second substance are detected. An intensity ratio Xc, as obtained by dividing the second intensity Xb with the first intensity Xa, is calculated.

摘要翻译： 示例性传感器芯片包括基板，形成在基板上被激发光照射的金属图案，以及设置在金属图案附近的第一物质和第二物质。 检测来自第一物质的第一表面增强拉曼散射光的第一强度Xa和来自第二物质的第二表面增强拉曼散射光的第二强度Xb。 计算通过将第二强度Xb除以第一强度Xa而得到的强度比Xc。