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公开(公告)号：US11041199B2
公开(公告)日：2021-06-22
申请号：US16721771
申请日：2019-12-19
Applicant: OMNIOME, INC.
Inventor： Michael John Erickstad , Eric Villarreal , Vyshnavi Balakrishnan , Xenia Aparicio , Rebecca McGinley , Arnold Oliphant
IPC: C12Q1/6869 , B01L3/00 , B01L7/00
Abstract: Provided herein and methods and apparatuses for sequencing nucleic acids. For example, provided is an analytical detection apparatus, including (a) a stage configured to support a flow cell; (b) a detector configured to observe a detection channel of the flow cell when the flow cell is supported by the stage; (c) a plurality of fluid delivery channels, wherein each of the fluid delivery channels fluidically connects a reservoir to the detection channel of the flow cell; and (d) a first heater configured to heat the plurality of fluid delivery channels.
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公开(公告)号：US10858703B2
公开(公告)日：2020-12-08
申请号：US16670106
申请日：2019-10-31
Applicant: Omniome, Inc.
Inventor： Dale Buermann , Michael John Erickstad , Rebecca McGinley , Alex Nemiroski , Harry Scott Rapoport , Arnold Oliphant
Abstract: An apparatus can include a vessel, a reference surface, a preload, a scan actuator, and a transmitter. The reference surface can form a structural loop with a detector. The preload can be configured to urge the vessel to contact an area on the reference surface. The scan actuator can be configured to slide the vessel along the reference surface in a scan dimension. The transmitter can be configured to direct signal from the vessel to a detector and/or direct energy from an energy source to the vessel, when the vessel is urged by the preload to contact the reference surface.
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3.发明申请公开(公告)号：US20190055598A1
公开(公告)日：2019-02-21
申请号：US16141896
申请日：2018-09-25
Applicant: Omniome, Inc.
Inventor： Dale Buermann , Michael John Erickstad , Rebecca McGinley , Alex Nemiroski , Harry Scott Rapoport , Arnold Oliphant
IPC: C12Q1/6874 , G01N21/64 , G01N21/03
Abstract: An apparatus can include a vessel, a reference surface, a preload, a scan actuator, and a transmitter. The reference surface can form a structural loop with a detector. The preload can be configured to urge the vessel to contact an area on the reference surface. The scan actuator can be configured to slide the vessel along the reference surface in a scan dimension. The transmitter can be configured to direct signal from the vessel to a detector and/or direct energy from an energy source to the vessel, when the vessel is urged by the preload to contact the reference surface.
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公开(公告)号：US10858701B2
公开(公告)日：2020-12-08
申请号：US15998727
申请日：2018-08-15
Applicant: Omniome, Inc.
Inventor： Dale Buermann , Michael John Erickstad , Rebecca McGinley , Alex Nemiroski , Harry Scott Rapoport , Arnold Oliphant
Abstract: An apparatus can include a vessel, a reference surface, a preload, a scan actuator, and a transmitter. The reference surface can form a structural loop with a detector. The preload can be configured to urge the vessel to contact an area on the reference surface. The scan actuator can be configured to slide the vessel along the reference surface in a scan dimension. The transmitter can be configured to direct signal from the vessel to a detector and/or direct energy from an energy source to the vessel, when the vessel is urged by the preload to contact the reference surface.
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公开(公告)号：US10710076B2
公开(公告)日：2020-07-14
申请号：US16700422
申请日：2019-12-02
Applicant: OMNIOME, INC.
Inventor： Arnold Oliphant , Alex Nemiroski , Julian Sean Alberni , Michael John Erickstad , Rebecca McGinley , Chad Fleischer , Eric Villarreal
IPC: B01L3/00 , C12Q1/6825 , C12Q1/6874
Abstract: An analytical system that includes a flow cell, a liquid delivery component, a gas delivery component and a bubble generator component, wherein the liquid delivery component is configured to deliver liquid from one or more reservoirs to the bubble generator component, wherein the gas delivery component is configured to deliver gas from one or more source to the bubble generator component, and wherein the bubble generator component is configured to mix liquids from the liquid delivery component with gas from the gas delivery component to deliver a fluid foam to the inside of the flow cell, wherein the fluid foam includes bubbles of the gas in the liquid.
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Patent Agency Ranking
6.发明申请公开(公告)号：US20200063201A1
公开(公告)日：2020-02-27
申请号：US16670106
申请日：2019-10-31
Applicant: Omniome, Inc.
Inventor： Dale Buermann , Michael John Erickstad , Rebecca McGinley , Alex Nemiroski , Harry Scott Rapoport , Arnold Oliphant
Abstract: An apparatus can include a vessel, a reference surface, a preload, a scan actuator, and a transmitter. The reference surface can form a structural loop with a detector. The preload can be configured to urge the vessel to contact an area on the reference surface. The scan actuator can be configured to slide the vessel along the reference surface in a scan dimension. The transmitter can be configured to direct signal from the vessel to a detector and/or direct energy from an energy source to the vessel, when the vessel is urged by the preload to contact the reference surface.
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公开(公告)号：US12077815B2
公开(公告)日：2024-09-03
申请号：US17325691
申请日：2021-05-20
Applicant: OMNIOME, INC.
Inventor： Michael John Erickstad , Eric Villarreal , Vyshnavi Balakrishnan , Xenia Aparicio , Rebecca McGinley , Arnold Oliphant
IPC: C12Q1/6869 , B01L3/00 , B01L7/00
CPC classification number: C12Q1/6869 , B01L3/502715 , B01L7/52 , B01L2300/0877 , B01L2300/1822
Abstract: Provided herein and methods and apparatuses for sequencing nucleic acids. For example, provided is an analytical detection apparatus, including (a) a stage configured to support a flow cell; (b) a detector configured to observe a detection channel of the flow cell when the flow cell is supported by the stage; (c) a plurality of fluid delivery channels, wherein each of the fluid delivery channels fluidically connects a reservoir to the detection channel of the flow cell; and (d) a first heater configured to heat the plurality of fluid delivery channels.
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公开(公告)号：US20210054453A1
公开(公告)日：2021-02-25
申请号：US17089570
申请日：2020-11-04
Applicant: Omniome, Inc.
Inventor： Dale Buermann , Michael John Erickstad , Rebecca McGinley , Alex Nemiroski , Harry Scott Rapoport , Arnold Oliphant
Abstract: An apparatus can include a vessel, a reference surface, a preload, a scan actuator, and a transmitter. The reference surface can form a structural loop with a detector. The preload can be configured to urge the vessel to contact an area on the reference surface. The scan actuator can be configured to slide the vessel along the reference surface in a scan dimension. The transmitter can be configured to direct signal from the vessel to a detector and/or direct energy from an energy source to the vessel, when the vessel is urged by the preload to contact the reference surface.
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公开(公告)号：US20200264204A1
公开(公告)日：2020-08-20
申请号：US16796623
申请日：2020-02-20
Applicant: Omniome, Inc.
Inventor： Matias Negatu , Alex Nemiroski , Drew Ival Frerichs , Dale Buermann , Michael John Erickstad , Rebecca McGinley , Harry Scott Rapoport , Arnold Oliphant , Eugene Pogrebinsky
IPC: G01N35/02
Abstract: A scanning apparatus that can include (a) a scan actuator including a linear actuator and a mount for a removeable vessel, wherein the mount has a mechanical fastener that is configured to engage a complementary mechanical fastener on the removeable vessel, and wherein the linear actuator is configured to translate the mount while the mechanical fastener engages the complementary mechanical fastener on the removeable vessel; (b) a reference surface; and (c) a preload configured to urge the vessel to contact the reference surface, wherein the linear actuator is configured to slide the vessel along the reference surface while the preload urges the vessel to contact the reference surface.
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10.发明申请公开(公告)号：US20190055596A1
公开(公告)日：2019-02-21
申请号：US15998727
申请日：2018-08-15
Applicant: Omniome, Inc.
Inventor： Dale Buermann , Michael John Erickstad , Rebecca McGinley , Alex Nemiroski , Harry Scott Rapoport , Arnold Oliphant
IPC: C12Q1/6874 , G01N21/03 , G01N21/64
Abstract: An apparatus can include a vessel, a reference surface, a preload, a scan actuator, and a transmitter. The reference surface can form a structural loop with a detector. The preload can be configured to urge the vessel to contact an area on the reference surface. The scan actuator can be configured to slide the vessel along the reference surface in a scan dimension. The transmitter can be configured to direct signal from the vessel to a detector and/or direct energy from an energy source to the vessel, when the vessel is urged by the preload to contact the reference surface.
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