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公开(公告)号:US20140079644A1
公开(公告)日:2014-03-20
申请号:US14083941
申请日:2013-11-19
发明人: Shyh-Dar Li , Mark John Ernsting , Wei-Lun Tang
IPC分类号: A61K9/14 , A61K31/4745 , A61K49/18 , A61K31/337
CPC分类号: A61K9/146 , A61K9/5161 , A61K31/337 , A61K31/4745 , A61K47/60 , A61K47/61 , A61K47/6935 , A61K47/6939 , A61K49/0032 , A61K49/0054 , A61K49/0093 , A61K49/1827 , A61K49/186 , A61K49/1863 , C08B3/06 , C08B11/12 , C08B13/00 , C08B15/005 , C08G65/329 , C08G81/00 , C08G2261/126 , C08L1/286 , C08L71/02 , C08L2203/02 , C08L2205/05 , Y10T428/2982 , C08L1/08
摘要: In one aspect, there is provided a compound comprising an acetylated carboxymethylcellulose (CMC-Ac) covalently linked to: at least one poly(ethylene glycol) (PEG), and at least one hydrophobic drug. In another aspect, a self-assembling nanoparticle composition comprising such compounds is provided.
摘要翻译: 在一个方面,提供了包含共价连接到:至少一种聚(乙二醇)(PEG)和至少一种疏水性药物的乙酰化羧甲基纤维素(CMC-Ac)的化合物。 另一方面,提供了包含这些化合物的自组装纳米颗粒组合物。