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公开(公告)号：US20180305431A1
公开(公告)日：2018-10-25
申请号：US15754395
申请日：2016-08-24
申请人： Novo Nordisk A/S
发明人： Peter Madsen , Anthony Murray , Martin Muenzel , Claudia Ulrich Hjoerringgaard , Susanne Hostrup , Tine Glendorf , Mathias Norrman , Christian Fledelius
摘要： The present invention is in the therapeutic fields of drugs for medical conditions relating to diabetes. More specifically the invention relates to novel acylated derivatives of human insulin analogues. The invention also provides pharmaceutical compositions comprising such insulin derivatives, and relates to the use of such derivatives for the treatment or prevention of medical conditions relating to diabetes.
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公开(公告)号：US20200172593A1
公开(公告)日：2020-06-04
申请号：US16784643
申请日：2020-02-07
申请人： Novo Nordisk A/S
发明人： Thomas Hoeg-Jensen , Palle Jakobsen , Ulrich Sensfuss , Christian Fledelius , Ulla Ribel-Madsen
IPC分类号： C07K14/62
摘要： The novel insulin derivates delivers, after administration to humans, insulin as a function of the glucose concentration in the tissue.
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公开(公告)号：US20190010206A1
公开(公告)日：2019-01-10
申请号：US15754173
申请日：2016-08-24
申请人： Novo Nordisk A/S
发明人： Peter Madsen , Martin Muenzel , Claudia Ulrich Hjoerringgaard , Susanne Hostrup , Tine Glendorf , Mathias Norrman , Christian Fledelius
IPC分类号： C07K14/62 , A61K38/28 , A61K31/4406 , A61P3/10
摘要： The present invention is in the therapeutic fields of drugs for medical conditions relating to diabetes. More specifically the invention relates to novel acylated derivatives of human insulin analogues. The invention also provides pharmaceutical compositions comprising such insulin derivatives, and relates to the use of such derivatives for the treatment or prevention of medical conditions relating to diabetes.
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公开(公告)号：US20180371045A1
公开(公告)日：2018-12-27
申请号：US16040684
申请日：2018-07-20
申请人： Novo Nordisk A/S
发明人： Thomas Hoeg-Jensen , Palle Jakobsen , Ulrich Sensfuss , Christian Fledelius , Ulla Ribel-Madsen
摘要： The novel insulin derivates delivers, after administration to humans, insulin as a function of the glucose concentration in the tissue.
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公开(公告)号：US11352406B2
公开(公告)日：2022-06-07
申请号：US15754395
申请日：2016-08-24
申请人： Novo Nordisk A/S
发明人： Peter Madsen , Anthony Murray , Martin Muenzel , Claudia Ulrich Hjoerringgaard , Susanne Hostrup , Tine Glendorf , Mathias Norrman , Christian Fledelius
摘要： The present invention is in the therapeutic fields of drugs for medical conditions relating to diabetes. More specifically the invention relates to novel acylated derivatives of human insulin analogues. The invention also provides pharmaceutical compositions comprising such insulin derivatives, and relates to the use of such derivatives for the treatment or prevention of medical conditions relating to diabetes.
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公开(公告)号：US20210024604A1
公开(公告)日：2021-01-28
申请号：US17065060
申请日：2020-10-07
申请人： Novo Nordisk A/S
发明人： Thomas Hoeg-Jensen , Palle Jakobsen , Ulrich Sensfuss , Christian Fledelius , Ulla Ribel-Madsen
IPC分类号： C07K14/62
摘要： The novel insulin derivates delivers, after administration to humans, insulin as a function of the glucose concentration in the tissue.
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公开(公告)号：US20180244743A1
公开(公告)日：2018-08-30
申请号：US15754342
申请日：2016-08-24
申请人： Novo Nordisk A/S
发明人： Peter Madsen , Claudia Ulrich Hjoerringgaard , Martin Muenzel , Susanne Hostrup , Christian Fledelius
摘要： The present invention is in the therapeutic fields of drugs for medical conditions relating to diabetes. More specifically the invention relates to novel acylated derivatives of human insulin analogues. The invention also provides pharmaceutical compositions comprising such insulin derivatives, and relates to the use of such derivatives for the treatment or prevention of medical conditions relating to diabetes.
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公开(公告)号：US10040839B2
公开(公告)日：2018-08-07
申请号：US15121206
申请日：2015-02-26
申请人： Novo Nordisk A/S
发明人： Peter Madsen , Susanne Hostrup , Martin Muenzel , Thomas Boerglum Kjeldsen , Claudia Ulrich Hjoerringgaard , Christian Fledelius
摘要： The present invention is in the therapeutic fields of drugs for medical conditions relating to diabetes. More specifically the invention relates to novel acylated derivatives of human insulin analogues. The invention also provides pharmaceutical compositions comprising such insulin derivatives, and relates to the use of such derivatives for the treatment or prevention of medical conditions relating to diabetes.
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公开(公告)号：US20200283493A1
公开(公告)日：2020-09-10
申请号：US16829769
申请日：2020-03-25
申请人： Novo Nordisk A/S
发明人： Peter Madsen , Martin Muenzel , Claudia Ulrich Hjoerringgaard , Susanne Hostrup , Tine Glendorf , Mathias Norrman , Christian Fledelius
IPC分类号： C07K14/62 , A61P3/10 , A61K31/4406 , A61K38/28
摘要： The present invention is in the therapeutic fields of drugs for medical conditions relating to diabetes. More specifically the invention relates to novel acylated derivatives of human insulin analogues. The invention also provides pharmaceutical compositions comprising such insulin derivatives, and relates to the use of such derivatives for the treatment or prevention of medical conditions relating to diabetes.
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公开(公告)号：US20170008945A1
公开(公告)日：2017-01-12
申请号：US15121206
申请日：2015-02-26
申请人： NOVO NORDISK A/S
发明人： Peter Madsen , Susanne Hostrup , Martin Muenzel , Thomas Boerglum Kjeldsen , Claudia Ulrich Hjoerringgaard , Christian Fledelius
摘要： The present invention is in the therapeutic fields of drugs for medical conditions relating to diabetes. More specifically the invention relates to novel acylated derivatives of human insulin analogues. The invention also provides pharmaceutical compositions comprising such insulin derivatives, and relates to the use of such derivatives for the treatment or prevention of medical conditions relating to diabetes.
摘要翻译： 本发明涉及与糖尿病有关的医疗状况的药物的治疗领域。 更具体地，本发明涉及人胰岛素类似物的新型酰化衍生物。 本发明还提供包含这种胰岛素衍生物的药物组合物，并且涉及这种衍生物用于治疗或预防与糖尿病相关的医学病症的用途。
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