公开(公告)号：US10040839B2

公开(公告)日：2018-08-07

申请号：US15121206

申请日：2015-02-26

申请人： Novo Nordisk A/S

发明人： Peter Madsen ,  Susanne Hostrup ,  Martin Muenzel ,  Thomas Boerglum Kjeldsen ,  Claudia Ulrich Hjoerringgaard ,  Christian Fledelius

IPC分类号： A61K38/28 ,  C07K14/62 ,  A61K47/22 ,  A61K38/00

CPC分类号： C07K14/62 ,  A61K38/00 ,  A61K38/28 ,  A61K47/22

摘要： The present invention is in the therapeutic fields of drugs for medical conditions relating to diabetes. More specifically the invention relates to novel acylated derivatives of human insulin analogues. The invention also provides pharmaceutical compositions comprising such insulin derivatives, and relates to the use of such derivatives for the treatment or prevention of medical conditions relating to diabetes.

公开(公告)号：US11352406B2

公开(公告)日：2022-06-07

申请号：US15754395

申请日：2016-08-24

申请人： Novo Nordisk A/S

发明人： Peter Madsen ,  Anthony Murray ,  Martin Muenzel ,  Claudia Ulrich Hjoerringgaard ,  Susanne Hostrup ,  Tine Glendorf ,  Mathias Norrman ,  Christian Fledelius

IPC分类号： C07K14/62 ,  A61K47/22 ,  A61K38/00

摘要： The present invention is in the therapeutic fields of drugs for medical conditions relating to diabetes. More specifically the invention relates to novel acylated derivatives of human insulin analogues. The invention also provides pharmaceutical compositions comprising such insulin derivatives, and relates to the use of such derivatives for the treatment or prevention of medical conditions relating to diabetes.

公开(公告)号：US20180244743A1

公开(公告)日：2018-08-30

申请号：US15754342

申请日：2016-08-24

申请人： Novo Nordisk A/S

发明人： Peter Madsen ,  Claudia Ulrich Hjoerringgaard ,  Martin Muenzel ,  Susanne Hostrup ,  Christian Fledelius

IPC分类号： C07K14/62 ,  A61P3/08

CPC分类号： C07K14/62 ,  A61K38/00 ,  A61P3/08

摘要： The present invention is in the therapeutic fields of drugs for medical conditions relating to diabetes. More specifically the invention relates to novel acylated derivatives of human insulin analogues. The invention also provides pharmaceutical compositions comprising such insulin derivatives, and relates to the use of such derivatives for the treatment or prevention of medical conditions relating to diabetes.

公开(公告)号：US20190010206A1

公开(公告)日：2019-01-10

申请号：US15754173

申请日：2016-08-24

申请人： Novo Nordisk A/S

发明人： Peter Madsen ,  Martin Muenzel ,  Claudia Ulrich Hjoerringgaard ,  Susanne Hostrup ,  Tine Glendorf ,  Mathias Norrman ,  Christian Fledelius

IPC分类号： C07K14/62 ,  A61K38/28 ,  A61K31/4406 ,  A61P3/10

摘要： The present invention is in the therapeutic fields of drugs for medical conditions relating to diabetes. More specifically the invention relates to novel acylated derivatives of human insulin analogues. The invention also provides pharmaceutical compositions comprising such insulin derivatives, and relates to the use of such derivatives for the treatment or prevention of medical conditions relating to diabetes.

公开(公告)号：US20180305431A1

公开(公告)日：2018-10-25

申请号：US15754395

申请日：2016-08-24

申请人： Novo Nordisk A/S

发明人： Peter Madsen ,  Anthony Murray ,  Martin Muenzel ,  Claudia Ulrich Hjoerringgaard ,  Susanne Hostrup ,  Tine Glendorf ,  Mathias Norrman ,  Christian Fledelius

IPC分类号： C07K14/62 ,  A61K47/22

CPC分类号： C07K14/62 ,  A61K38/00 ,  A61K47/22

摘要： The present invention is in the therapeutic fields of drugs for medical conditions relating to diabetes. More specifically the invention relates to novel acylated derivatives of human insulin analogues. The invention also provides pharmaceutical compositions comprising such insulin derivatives, and relates to the use of such derivatives for the treatment or prevention of medical conditions relating to diabetes.

公开(公告)号：US20200283493A1

公开(公告)日：2020-09-10

申请号：US16829769

申请日：2020-03-25

申请人： Novo Nordisk A/S

发明人： Peter Madsen ,  Martin Muenzel ,  Claudia Ulrich Hjoerringgaard ,  Susanne Hostrup ,  Tine Glendorf ,  Mathias Norrman ,  Christian Fledelius

IPC分类号： C07K14/62 ,  A61P3/10 ,  A61K31/4406 ,  A61K38/28

摘要： The present invention is in the therapeutic fields of drugs for medical conditions relating to diabetes. More specifically the invention relates to novel acylated derivatives of human insulin analogues. The invention also provides pharmaceutical compositions comprising such insulin derivatives, and relates to the use of such derivatives for the treatment or prevention of medical conditions relating to diabetes.

公开(公告)号：US20170008945A1

公开(公告)日：2017-01-12

申请号：US15121206

申请日：2015-02-26

申请人： NOVO NORDISK A/S

发明人： Peter Madsen ,  Susanne Hostrup ,  Martin Muenzel ,  Thomas Boerglum Kjeldsen ,  Claudia Ulrich Hjoerringgaard ,  Christian Fledelius

IPC分类号： C07K14/62 ,  A61K38/28 ,  A61K47/22

CPC分类号： C07K14/62 ,  A61K38/00 ,  A61K38/28 ,  A61K47/22

摘要： The present invention is in the therapeutic fields of drugs for medical conditions relating to diabetes. More specifically the invention relates to novel acylated derivatives of human insulin analogues. The invention also provides pharmaceutical compositions comprising such insulin derivatives, and relates to the use of such derivatives for the treatment or prevention of medical conditions relating to diabetes.

摘要翻译： 本发明涉及与糖尿病有关的医疗状况的药物的治疗领域。 更具体地，本发明涉及人胰岛素类似物的新型酰化衍生物。 本发明还提供包含这种胰岛素衍生物的药物组合物，并且涉及这种衍生物用于治疗或预防与糖尿病相关的医学病症的用途。