公开(公告)号：US20230025630A1

公开(公告)日：2023-01-26

申请号：US17292891

申请日：2019-11-11

Applicant: Novartis AG

Inventor： Shomir GHOSH ,  Jason KATZ ,  William ROUSH ,  Hans Martin SEIDEL ,  Dong-Ming SHEN ,  Shankar VENKATRAMAN

IPC: C07D417/06 ,  C07D417/12 ,  C07D417/14 ,  C07D401/06 ,  A61P35/00

Abstract: In one aspect, compounds of Formula AA, or a pharmaceutically acceptable salt thereof, are featured: or a pharmaceutically acceptable salt thereof, wherein the variables shown in Formula A can be as defined anywhere herein.

公开(公告)号：US20230031406A1

公开(公告)日：2023-02-02

申请号：US17292881

申请日：2019-11-11

Applicant: Novartis AG

Inventor： Shomir GHOSH ,  Gary GLICK ,  Jason KATZ ,  William ROUSH ,  Hans Martin SEIDEL ,  Dong-Ming SHEN ,  Shankar VENKATRAMAN

IPC: C07D409/12 ,  A61P1/00 ,  C07D417/12 ,  C07D221/16 ,  C07D401/12 ,  C07D221/18 ,  C07D498/04 ,  C07D471/04 ,  C07D498/20 ,  C07D487/04 ,  C07D491/04 ,  C07D495/04 ,  C07D409/14 ,  C07H15/26

Abstract: In one aspect, compounds of Formula AA, or a pharmaceutically acceptable salt thereof, are featured: or a pharmaceutically acceptable salt thereof, wherein the variables shown in Formula A can be as defined anywhere herein.

公开(公告)号：US20230416211A1

公开(公告)日：2023-12-28

申请号：US18319630

申请日：2023-05-18

Applicant: NOVARTIS AG

Inventor： Luigi FRANCHI ,  Shomir GHOSH ,  Gary GLICK ,  Jason KATZ ,  Anthony William OPIPARI ,  William ROUSH ,  Hans Martin SEIDEL ,  Dong-Ming SHEN ,  Shankar VENKATRAMAN ,  David Guenther WINKLER

IPC: C07D277/36 ,  C07D307/64 ,  C07D333/34 ,  C07C307/06 ,  C07D215/36 ,  C07D231/18 ,  C07D239/26 ,  C07D263/46 ,  C07D307/79 ,  C07D317/62 ,  C07D487/04

CPC classification number: C07D277/36 ,  C07D307/64 ,  C07D333/34 ,  C07C307/06 ,  C07D215/36 ,  C07D231/18 ,  C07D239/26 ,  C07D263/46 ,  C07D307/79 ,  C07D317/62 ,  C07D487/04 ,  C07C335/42

Abstract: In one aspect, compounds of Formula AA, or a pharmaceutically acceptable salt thereof, are featured:






or a pharmaceutically acceptable salt thereof, wherein the variables shown in Formula A can be as defined anywhere herein.

公开(公告)号：US20230062815A1

公开(公告)日：2023-03-02

申请号：US17496375

申请日：2021-10-07

Applicant: Novartis AG

Inventor： Luigi FRANCHI ,  Shomir GHOSH ,  Gary GLICK ,  Jason KATZ ,  Anthony William OPIPARI, JR. ,  William ROUSH ,  Hans Martin SEIDEL ,  Dong-Ming SHEN ,  Shankar VENKATRAMAN ,  David Guenther WINKLER

IPC: C07D277/36 ,  C07D215/36 ,  C07D231/18 ,  C07D239/26 ,  C07D263/46 ,  C07D307/64 ,  C07D307/79 ,  C07D317/62 ,  C07D333/34 ,  C07D487/04 ,  C07C307/06

Abstract: In one aspect, compounds of Formula AA, or a pharmaceutically acceptable salt thereof, are featured: or a pharmaceutically acceptable salt thereof, wherein the variables shown in Formula A can be as defined anywhere herein.

公开(公告)号：US20230024859A1

公开(公告)日：2023-01-26

申请号：US17292887

申请日：2019-11-11

Applicant: Novartis AG

Inventor： Jason KATZ ,  William ROUSH ,  Hans Martin SEIDEL ,  Dong-Ming SHEN ,  Shankar VENKATRAMAN

IPC: C07D417/12 ,  C07D275/06 ,  C07D281/10 ,  C07D513/04 ,  C07D279/02 ,  C07D285/18 ,  C07D285/36 ,  C07D513/10 ,  A61K45/06 ,  A61P35/00

Abstract: In one aspect, compounds of Formula AA, or a pharmaceutically acceptable salt thereof, are featured or a pharmaceutically acceptable salt thereof, wherein the variables shown in Formula A can be as defined anywhere herein.

公开(公告)号：US20230059136A1

公开(公告)日：2023-02-23

申请号：US17293787

申请日：2019-11-14

Applicant: Novartis AG

Inventor： Luigi FRANCHI ,  Shomir GHOSH ,  Gary GLICK ,  Jason KATZ ,  Anthony William OPIPARI, Jr. ,  William ROUSH ,  Hans Martin SEIDEL ,  Dong-Ming SHEN ,  Shankar VENKATRAMAN ,  David Guenther WINKLER

IPC: C07D277/80 ,  C07D333/34 ,  C07C311/57 ,  C07D231/12 ,  C07D317/60 ,  C07D307/36 ,  C07D417/12

Abstract: In one aspect, compounds of Formula AA, or a pharmaceutically acceptable salt thereof, are featured: Formula AA or a pharmaceutically acceptable salt thereof, wherein the variables shown in Formula A can be as defined anywhere herein.

公开(公告)号：US20220387397A1

公开(公告)日：2022-12-08

申请号：US17287837

申请日：2019-10-23

Applicant: Novartis AG

Inventor： William ROUSH ,  Shankar VENKATRAMAN ,  Shomir GHOSH ,  Dong-Ming SHEN ,  Jason KATZ ,  Hans Martin SEIDEL

IPC: A61K31/426 ,  A61P29/00 ,  A61P1/00 ,  A61K45/06 ,  A61K39/395 ,  A61K31/341 ,  C07D307/64 ,  C07D277/36 ,  C07C311/51 ,  A61K31/18

Abstract: In one aspect, compounds of Formula A, or a pharmaceutically acceptable salt thereof, are featured (Formula A) or a pharmaceutically acceptable salt thereof, wherein the variables shown in Formula A can be as defined anywhere herein.

公开(公告)号：US20240391884A1

公开(公告)日：2024-11-28

申请号：US18779915

申请日：2024-07-22

Applicant: Novartis AG

Inventor： Luigi FRANCHI ,  Shomir GHOSH ,  Gary GLICK ,  Jason KATZ ,  Anthony William OPIPARI, Jr. ,  William ROUSH ,  Hans Martin SEIDEL ,  Dong-Ming SHEN ,  Shankar VENKATRAMAN ,  David Guenther WINKLER

IPC: C07D265/30 ,  A61K45/06 ,  A61P1/00 ,  A61P11/00 ,  A61P19/08 ,  A61P35/00 ,  C07C381/10 ,  C07D209/26 ,  C07D211/78 ,  C07D215/06 ,  C07D231/12 ,  C07D239/26 ,  C07D239/36 ,  C07D261/08 ,  C07D263/46 ,  C07D277/36 ,  C07D317/50 ,  C07D333/34 ,  C07D401/12 ,  C07D409/12 ,  C07D417/12

Abstract: In one aspect, compounds of Formula AA, or a pharmaceutically acceptable salt thereof, are featured: or a pharmaceutically acceptable salt thereof, wherein the variables shown in Formula A can be as defined anywhere herein.

公开(公告)号：US20230079631A1

公开(公告)日：2023-03-16

申请号：US17662863

申请日：2022-05-11

Applicant: Novartis AG

Inventor： Luigi FRANCHI ,  Shomir GHOSH ,  Gary GLICK ,  Jason KATZ ,  Anthony William OPIPARI, JR. ,  William ROUSH ,  Hans Martin SEIDEL ,  Dong-Ming SHEN ,  Shankar VENKATRAMAN ,  David Guenther WINKLER

IPC: C07D265/30 ,  A61P1/00 ,  A61P11/00 ,  A61P19/08 ,  A61P35/00 ,  C07C381/10 ,  C07D209/26 ,  C07D211/78 ,  C07D215/06 ,  C07D231/12 ,  C07D239/26 ,  C07D239/36 ,  C07D261/08 ,  C07D263/46 ,  C07D277/36 ,  C07D317/50 ,  C07D333/34 ,  C07D401/12 ,  C07D409/12 ,  C07D417/12

Abstract: In one aspect, compounds of Formula AA, or a pharmaceutically acceptable salt thereof, are featured: or a pharmaceutically acceptable salt thereof, wherein the variables shown in Formula A can be as defined anywhere herein.

公开(公告)号：US20230051589A1

公开(公告)日：2023-02-16

申请号：US17293781

申请日：2019-11-14

Applicant: Novartis AG

Inventor： Luigi FRANCHI ,  Shomir GHOSH ,  Gary GLICK ,  Jason KATZ ,  Anthony William OPIPARI, Jr. ,  William ROUSH ,  Hans Martin SEIDEL ,  Dong-Ming SHEN ,  Shankar VENKATRAMAN ,  David Guenther WINKLER

IPC: A61K31/426 ,  A61K45/06 ,  A61K31/64 ,  C07D307/64 ,  C07D277/36 ,  A61K31/381 ,  C07D333/34 ,  C07D409/12 ,  A61K31/4436 ,  A61K31/18 ,  C07C381/10 ,  C07D231/18 ,  A61K31/415 ,  A61K31/36 ,  A61K31/4406 ,  A61K31/47 ,  C07D317/62 ,  C07D213/71 ,  C07D215/36 ,  C07D487/04 ,  C07D405/12 ,  A61K31/4188 ,  A61K31/397 ,  C07D205/04 ,  C07D295/096 ,  A61K31/5375 ,  C07D207/10 ,  A61K31/40 ,  A61K31/4015 ,  C07D207/12 ,  C07D333/72 ,  A61K31/451 ,  C07D211/24 ,  C07D495/04 ,  A61K31/4365 ,  A61P1/00 ,  A61P37/06

Abstract: In one aspect, compounds of Formula AA, or a pharmaceutically acceptable salt thereof, are featured: Formula AA or a pharmaceutically acceptable salt thereof, wherein the variables shown in Formula A can be as defined anywhere herein.