公开(公告)号：US12195442B2

公开(公告)日：2025-01-14

申请号：US17286888

申请日：2019-10-23

Applicant: Nippon Soda Co., Ltd.

Inventor： Keita Sakanishi ,  Norifumi Sakiyama ,  Hikaru Aoyama ,  Maki Matsui ,  Takao Iwasa ,  Tomomi Kobayashi ,  Daisuke Ushijima ,  Keita Azuma ,  Masanori Sumino ,  Yasuhiko Ashikari ,  Kotaro Shibayama ,  Riho Taguchi

IPC: C07D401/04 ,  A01N43/50

Abstract: An object of the present invention is to provide a (hetero)aryl imidazole compound that is excellent in pest control activity, particularly, insecticidal activity and/or acaricidal activity, is excellent in safety, and may be industrially advantageously synthesized. The (hetero)aryl imidazole compound of the present invention is a compound represented by the formula (I) an N-oxide compound, stereoisomer, tautomer or hydrate thereof or a salt of any of these compounds. In the formula (I), B1 represents a nitrogen atom or CH; X represents a substituted or unsubstituted C3-8 cycloalkyl group; R1 represents a substituted or unsubstituted C1-6 alkylthio group or a substituted or unsubstituted C1-6 alkylsulfonyl group; R2 represents a substituted or unsubstituted C1-6 alkyl group; and R represents a substituted or unsubstituted C2-6 alkenyl group.

公开(公告)号：US11180485B2

公开(公告)日：2021-11-23

申请号：US16329198

申请日：2017-09-13

Applicant: Nippon Soda Co., Ltd.

Inventor： Keita Sakanishi ,  Takao Iwasa ,  Hikaru Aoyama ,  Norifumi Sakiyama ,  Daisuke Ushijima ,  Maki Matsui ,  Tomomi Kobayashi

IPC: C07D403/14 ,  C07D401/14 ,  A01N43/54 ,  C07D403/04 ,  A01N43/653 ,  A61K31/506 ,  A01N43/50 ,  C07D233/64 ,  C07D401/04 ,  A61P31/10 ,  A01N43/56 ,  C07D403/10 ,  A61P31/14 ,  C07D413/10

Abstract: A compound represented by Formula (I), or a salt thereof: wherein, R1 represents an unsubstituted or substituted C1-6 alkylthio group, or the like; A1 represents a nitrogen atom or CH; A2 represents a nitrogen atom or CR2; R2 and R3 each independently represents a hydrogen atom, an unsubstituted or substituted C6-10 aryl group, an unsubstituted or substituted 3- to 6-membered heterocyclyl group, or the like; B1 and B2 each independently represents a nitrogen atom or CR5, with the proviso that B1 and B2 do not represent CR5 at the same time, wherein R5 represents a hydrogen atom, an unsubstituted or substituted C1-6 alkyl group, or the like; R4 represents an unsubstituted or substituted C1-6 alkyl group, or the like, and R4 binds to any one of nitrogen atoms forming an imidazole ring or a triazole ring; and Ar represents an unsubstituted or substituted C6-10 aryl group or the like.

公开(公告)号：US11078181B2

公开(公告)日：2021-08-03

申请号：US16469937

申请日：2017-12-14

Applicant: Nippon Soda Co., Ltd.

Inventor： Keita Sakanishi ,  Takao Iwasa ,  Norifumi Sakiyama ,  Hikaru Aoyama ,  Tomomi Kobayashi

IPC: C07D401/04 ,  C07D401/14 ,  A01N43/56 ,  A01N43/653

Abstract: A compound represented by the following Formula (I) or a salt thereof, as well as a formulation for controlling harmful organisms, and in particular, an insecticidal formulation, a miticidal formulation, a formulation for controlling ectoparasites or a formulation for controlling or killing endoparasites, which contains at least one compound selected from the compounds of Formula (I) and salts thereof as an active ingredient wherein, each of R1 and R2 independently represents a hydrogen atom, a substituted or unsubstituted C1-6 alkyl group, or the like, with the proviso that when R2 represents a hydrogen atom, R1 represents a substituted or unsubstituted C6-10 aryl group or a substituted or unsubstituted 3- to 6-membered heterocyclyl group; R3 represents a C1-6 alkylthio group or the like; each of R4 and R5 independently represents a hydrogen atom, a halogeno group or the like; and Ar represents a substituted or unsubstituted C6-10 aryl group, or a substituted or unsubstituted 5- to 6-membered heteroaryl group.

公开(公告)号：US10793520B2

公开(公告)日：2020-10-06

申请号：US16316710

申请日：2017-08-28

Applicant: Nippon Soda Co., Ltd.

Inventor： Jun Takahashi ,  Tetsuro Kato ,  Takao Iwasa

IPC: C07C311/09 ,  A01N41/06 ,  A61P33/00 ,  A01N43/40 ,  C07D277/28 ,  A61P33/14 ,  A61K31/426 ,  C07D213/74 ,  A01N43/653 ,  A01N43/78 ,  C07D277/44 ,  A61K31/44 ,  A61K31/16 ,  C07C303/40 ,  C07C303/36

Abstract: A compound represented by formula (I) or a salt thereof. In formula (I), R1 and R4 each independently represent a hydrogen atom, or an unsubstituted or substituted C1 to C6 alkyl group or the like. R2 represents a hydrogen atom, or an unsubstituted or substituted C1 to C6 alkyl group or the like. R3 represents an unsubstituted or substituted C1 to C6 alkyl group or the like. R5 represents a C1 to C6 haloalkyl group or the like. G represents an oxygen atom or a sulfur atom. R6 and R7 each independently represent a hydrogen atom, or an unsubstituted or substituted C1 to C6 alkyl group or the like. n represents 0 or 1. R8 and R9 each independently represent a hydrogen atom, or an unsubstituted or substituted C1 to C6 alkyl group. Ar represents an unsubstituted or substituted C6 to C10 aryl group or the like.

公开(公告)号：US10548316B2

公开(公告)日：2020-02-04

申请号：US15735713

申请日：2016-06-17

Applicant: Nippon Soda Co., Ltd.

Inventor： Hikaru Aoyama ,  Maki Matsui ,  Keita Sakanishi ,  Takao Iwasa ,  Tomomi Kobayashi ,  Koichi Hirata

IPC: A01N43/56 ,  A01N43/653 ,  A01N43/90 ,  A01N47/18 ,  C07D231/12 ,  C07D231/16 ,  C07D231/40 ,  C07D401/04 ,  C07D403/04 ,  C07D249/06

Abstract: The present invention provides a compound represented by formula (I), (in the formula, A1 and A2 each independently represents a carbon atom or a nitrogen atom; X1 represents an unsubstituted or substituted C1-6 alkyl group or the like; n represents an integer of 0 to 4; R1 represents an unsubstituted or substituted C1-6 alkylthio group or the like; B1 and B4 each independently represent a carbon atom, a nitrogen atom or the like; R2 and R3 each independently represent a hydrogen atom, a halogeno group or the like; Ar represents an unsubstituted or substituted C6-10 aryl group or the like) or a salt thereof, and a harmful organism control agent including thereof.

公开(公告)号：US20160008321A1

公开(公告)日：2016-01-14

申请号：US14771866

申请日：2014-02-28

Applicant: NIPPON SODA CO., LTD.

Inventor： Takao Iwasa ,  Koichi HIRATA

IPC: A61K31/382 ,  A01N43/10 ,  A01N43/16 ,  A61K31/381 ,  A01N43/18 ,  A61K31/351

CPC classification number: A61K31/382 ,  A01N43/10 ,  A01N43/16 ,  A01N43/18 ,  A61K31/351 ,  A61K31/381 ,  C07D333/36 ,  C07D335/02

Abstract: wherein, in formula (III), X1 represents a C1-6 alkyl group which is unsubstituted or has a substituent, or other groups; ml represents any integer of 0 to 5; A represents an oxygen atom or a sulfur atom; each of R1 and R2 independently represents a hydrogen atom, a C1-6 alkyl group which is unsubstituted or has a substituent, or other groups; R5 represents a hydrogen atom or a C1-6 alkyl group which is unsubstituted or has a substituent; B represents an oxygen atom or a sulfur atom; Q2 represents a C7-11 aralkyl group which is unsubstituted or has a substituent X2, or other groups; and each of R3a, R3b, R4a, and R4b independently represents a hydrogen atom, a C1-6 alkyl group which is unsubstituted or has a substituent, or other groups.

Abstract translation: 其中，在式（III）中，X 1表示未被取代或具有取代基的C 1-6烷基或其它基团; ml表示0〜5的任意整数， A表示氧原子或硫原子; R 1和R 2各自独立地表示氢原子，未被取代或具有取代基的C 1-6烷基或其它基团; R5表示氢原子或未取代或具有取代基的C1-6烷基; B表示氧原子或硫原子; Q2表示未取代或具有取代基X2的C7-11芳烷基或其他基团; R3a，R3b，R4a和R4b各自独立地表示氢原子，未取代或具有取代基的C1-6烷基或其它基团。

公开(公告)号：US11445726B2

公开(公告)日：2022-09-20

申请号：US16764253

申请日：2018-11-27

Applicant: Nippon Soda Co., Ltd.

Inventor： Takao Iwasa ,  Katsunori Tanaka ,  Atsuko Nabeta ,  Riho Taguchi ,  Kotaro Shibayama ,  Hiroto Suzuki ,  Rie Sakamoto ,  Miho Takahashi ,  Tsuyoshi Hoya

IPC: A01N43/40 ,  A01N43/54 ,  A01N43/56 ,  A01N43/60 ,  A01N43/76 ,  A01N43/78 ,  A01N43/82 ,  C07D213/89 ,  C07D401/12 ,  C07D405/12 ,  C07D409/12 ,  C07D413/12 ,  C07D417/12

Abstract: A compound represented by formula (I) or formula (II): wherein, A represents an oxygen atom or a sulfur atom; X1 represents a halogeno group, a substituted or unsubstituted C1-6 alkyl group and so on; m represents the number of X1 and is any integer of 0 to 5; any two of X1 may be bound together to form a bivalent hydrocarbon group; Y represents a single bond or a substituted or unsubstituted C2-6 alkenylene group; Q1 represents a substituted or unsubstituted C6-10 arylene group or a substituted or unsubstituted 6- to 10-membered heteroarylene group; Q2 represents a substituted or unsubstituted C6-10 aryl group or a substituted or unsubstituted 5- to 6-membered heteroaryl group; Zq− represents a counter ion; and q represents a valence of the counter ion and is 1 or 2.

公开(公告)号：US11427564B2

公开(公告)日：2022-08-30

申请号：US16624636

申请日：2018-06-22

Applicant: Nippon Soda Co., Ltd.

Inventor： Keita Sakanishi ,  Hikaru Aoyama ,  Norifumi Sakiyama ,  Takao Iwasa ,  Daisuke Ushijima ,  Maki Matsui

IPC: C07D401/04 ,  C07D401/14 ,  C07D403/04 ,  C07D403/14 ,  A01N43/82

Abstract: A compound represented by a formula (I) or a salt thereof: wherein A1 represents CR1 or a nitrogen atom; A2 represents CR2 or a nitrogen atom; A3 represents CR3 or a nitrogen atom, provided that two or more of A1 to A3 do not represent nitrogen atoms at the same time; R1, R2 and R3 each independently represent a hydrogen atom or the like; B1 represents CH or a nitrogen atom; R4 represents a substituted or unsubstituted C1-6 alkyl group or the like; R5 represents a substituted or unsubstituted C1-6 alkylthio group or the like; and R6 represents a substituted or unsubstituted C1-6 alkyl group or the like.

公开(公告)号：US11178872B2

公开(公告)日：2021-11-23

申请号：US16098986

申请日：2017-05-02

Applicant: Nippon Soda Co., Ltd.

Inventor： Jun Iwata ,  Fumiya Nishio ,  Takao Iwasa ,  Satoshi Makino ,  Koichi Hirata

IPC: C07D413/14 ,  A01N43/90 ,  A01N43/42 ,  C07D401/06 ,  C07D491/107 ,  A01N47/02 ,  A01N43/54 ,  A01N43/40 ,  A01N43/52 ,  A01N43/56 ,  A01N43/82 ,  C07D401/14 ,  C07D491/056

Abstract: A compound represented by a formula (I), or a salt thereof: wherein Ar1 is a substituted or unsubstituted C6-10 aryl group, or the like; the number of X1 groups that can be substituted on Ar1 is 5 or less; X1 is a halogeno group, a substituted or unsubstituted C1-6 alkyl group, or the like; Z is a single bond, a sulfur atom, or an oxygen atom; A is a nitrogen atom or a carbon atom; X2 is a halogeno group, a substituted or unsubstituted C1-6 alkyl group, or the like; m is an integer of 0 to 2 when A is a nitrogen atom and is an integer of 0 to 3 when A is a carbon atom; R1 to R4 and R6 to R9 each independently represent a hydrogen atom, a substituted or unsubstituted C1-6 alkyl group, or the like; R5 is a hydrogen atom, a substituted or unsubstituted C1-6 alkyl group, or the like; k represents the number of CR6R7 moieties in a parenthesis and is 0 or 1; h represents the number of CR3R4 moieties in a parenthesis and is 0 or 1; and Ar is a substituted or unsubstituted C6-10 aryl group, or the like.

公开(公告)号：US10021880B2

公开(公告)日：2018-07-17

申请号：US15501921

申请日：2015-08-11

Applicant: Nippon Soda Co., Ltd.

Inventor： Hikaru Aoyama ,  Maki Matsui ,  Takao Iwasa ,  Kazushige Fujii ,  Tomomi Kobayashi ,  Keita Sakanishi

IPC: C07D233/64 ,  C07D233/90 ,  C07D233/92 ,  A01N43/50 ,  C07D401/04 ,  C07D403/04 ,  A01N43/56 ,  C07D401/14 ,  A01N43/54 ,  C07D405/04 ,  A01N43/58 ,  C07D409/04 ,  C07D417/14 ,  A01N43/74

Abstract: The present invention provides a compound represented by formula (I) or salt thereof (in the formula, A1 and A2 each independently represents a nitrogen atom or the like, B1, B2, B3 and B4 each independently represents a carbon atom or nitrogen atom, X1 represents an unsubstituted or substituted C1-6 alkyl group or the like, n represents a number of X1 and represents an integer of 0-4, R1 represents a halogeno group or the like, R2 represents an unsubstituted or substituted C1-6 alkyl group or the like, m represents a number of the oxide group bonding with the nitrogen atom which does not bond with R2 on the imidazole ring, and represents 0 or 1, R3 represents a hydrogen atom or the like, Ar represents an unsubstituted or substituted C6-10 aryl group.