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    Highly stable surface plasmon resonance plates, microarrays, and methods
    1.
    发明授权
    Highly stable surface plasmon resonance plates, microarrays, and methods 有权
    高度稳定的表面等离子体共振板，微阵列和方法

    公开(公告)号：US07463358B2

    公开(公告)日：2008-12-09

    申请号：US11296659

    申请日：2005-12-06

    申请人： Nick Wolf ,  Danliang Jin ,  Anna M. Barklund ,  Raluca Dinu

    发明人： Nick Wolf ,  Danliang Jin ,  Anna M. Barklund ,  Raluca Dinu

    IPC分类号： G01N21/55

    CPC分类号： G01N33/54373 ,  G01N33/553 ,  Y10T428/12493 ,  Y10T428/12535 ,  Y10T428/12556 ,  Y10T428/1259 ,  Y10T428/12597 ,  Y10T428/12861 ,  Y10T428/31663 ,  Y10T436/143333

    摘要： An article, process, and method for surface plasmon resonance plates are described. A substrate is covered with a thin metal film onto which a second thin metal film is deposited. The surface of the second thin metal film is converted to the metal oxide which is used to covalently bond organosilanes to the surface. Reactive organosilanes containing terminal bonding groups are arranged in a plurality of spots that are surrounded by inert organosilanes. Biomolecule attachment to the binding group is detected or measured from surface plasmon signals from the first thin metal film.

    摘要翻译： 描述了表面等离子体共振板的制品，工艺和方法。 衬底被薄金属膜覆盖，其上沉积有第二薄金属膜。 将第二薄金属膜的表面转化为用于将有机硅烷共价键合到表面的金属氧化物。 含有末端键合基团的反应性有机硅烷排列成被惰性有机硅烷包围的多个点。 通过来自第一薄金属膜的表面等离子体信号检测或测量与结合基团的生物分子附着。

    Methods for making and using SPR microarrays
    3.
    发明授权
    Methods for making and using SPR microarrays 有权
    制备和使用SPR微阵列的方法

    公开(公告)号：US08094315B2

    公开(公告)日：2012-01-10

    申请号：US12330384

    申请日：2008-12-08

    申请人： Nicholas Adam Wolf ,  Danliang Jin ,  Anna Barklund ,  Raluca Dinu

    发明人： Nicholas Adam Wolf ,  Danliang Jin ,  Anna Barklund ,  Raluca Dinu

    IPC分类号： G01N21/55

    CPC分类号： G01N33/54373 ,  G01N33/553 ,  Y10T428/12493 ,  Y10T428/12535 ,  Y10T428/12556 ,  Y10T428/1259 ,  Y10T428/12597 ,  Y10T428/12861 ,  Y10T428/31663 ,  Y10T436/143333

    摘要： An article, process, and method for surface plasmon resonance plates are described. A substrate is covered with a thin metal film onto which a second thin metal film is deposited. The surface of the second thin metal film is converted to the metal oxide which is used to covalently bond organosilanes to the surface. Reactive organosilanes containing terminal bonding groups are arranged in a plurality of spots that are surrounded by inert organosilanes. Biomolecule attachment to the binding group is detected or measured from surface plasmon signals from the first thin metal film.

    摘要翻译： 描述了表面等离子体共振板的制品，工艺和方法。 衬底被薄金属膜覆盖，其上沉积有第二薄金属膜。 将第二薄金属膜的表面转化为用于将有机硅烷共价键合到表面的金属氧化物。 含有末端键合基团的反应性有机硅烷排列成被惰性有机硅烷包围的多个点。 通过来自第一薄金属膜的表面等离子体信号检测或测量与结合基团的生物分子附着。

    INTEGRATED ELECTRO-OPTIC DEVICE AND METHOD OF MAKING
    4.
    发明申请
    INTEGRATED ELECTRO-OPTIC DEVICE AND METHOD OF MAKING 有权
    集成电光器件及其制造方法

    公开(公告)号：US20100040322A1

    公开(公告)日：2010-02-18

    申请号：US12246957

    申请日：2008-10-07

    申请人： Bing Li ,  Raluca Dinu ,  Eric Miller ,  Danliang Jin ,  Hui Chen ,  Christopher A. Wiklof

    发明人： Bing Li ,  Raluca Dinu ,  Eric Miller ,  Danliang Jin ,  Hui Chen ,  Christopher A. Wiklof

    IPC分类号： G02B6/12 ,  G02F1/035 ,  H01L21/02

    CPC分类号： G02F1/065 ,  G02B6/1221

    摘要： An electro-optic polymer semiconductor integrated circuit includes one or more doped regions configured to drive one or more electrodes, and the electrodes are configured to drive a juxtaposed electro-optic core. The assembly may include a planarization layer disposed at least partially coplanar with the electrodes. The circuit may include an integrated multiplexer, driver configured to receive a signal from the multiplexer, at least one high speed electrode configured to be driven by the driver and modulate light energy passed through a hyperpolarizable poled chromophore regions disposed near the high speed electrode. The circuit may include a calibration storage circuit. The circuit may include, during fabrication, structures to provide voltage to a buried electrode and a shield to prevent damage from the poling field.

    摘要翻译： 电光聚合物半导体集成电路包括被配置为驱动一个或多个电极的一个或多个掺杂区域，并且电极被配置为驱动并置的电光芯。 组件可以包括至少部分地与电极共面设置的平坦化层。 电路可以包括集成多路复用器，被配置为从多路复用器接收信号的驱动器，配置成由驱动器驱动的至少一个高速电极，并调制通过设置在高速电极附近的超极化极化发色团区域的光能。 电路可以包括校准存储电路。 该电路在制造期间可以包括向掩埋电极和屏蔽层提供电压以防止来自极化场的损伤的结构。

    Integrated electro-optic device and method of making
    6.
    发明授权
    Integrated electro-optic device and method of making 有权
    集成电光装置及其制作方法

    公开(公告)号：US08483524B2

    公开(公告)日：2013-07-09

    申请号：US12246957

    申请日：2008-10-07

    申请人： Bing Li ,  Raluca Dinu ,  Eric Miller ,  Danliang Jin ,  Hui Chen ,  Christopher A. Wiklof

    发明人： Bing Li ,  Raluca Dinu ,  Eric Miller ,  Danliang Jin ,  Hui Chen ,  Christopher A. Wiklof

    IPC分类号： G02B6/12 ,  G02B6/00 ,  G02F1/035

    CPC分类号： G02F1/065 ,  G02B6/1221

    摘要： An electro-optic polymer semiconductor integrated circuit includes one or more doped regions configured to drive one or more electrodes, and the electrodes are configured to drive a juxtaposed electro-optic core. The assembly may include a planarization layer disposed at least partially coplanar with the electrodes. The circuit may include an integrated multiplexer, driver configured to receive a signal from the multiplexer, at least one high speed electrode configured to be driven by the driver and modulate light energy passed through a hyperpolarizable poled chromophore regions disposed near the high speed electrode. The circuit may include a calibration storage circuit. The circuit may include, during fabrication, structures to provide voltage to a buried electrode and a shield to prevent damage from the poling field.

    摘要翻译： 电光聚合物半导体集成电路包括被配置为驱动一个或多个电极的一个或多个掺杂区域，并且电极被配置为驱动并置的电光芯。 组件可以包括至少部分地与电极共面设置的平坦化层。 电路可以包括集成多路复用器，被配置为从多路复用器接收信号的驱动器，配置成由驱动器驱动的至少一个高速电极，并调制通过设置在高速电极附近的超极化极化发色团区域的光能。 电路可以包括校准存储电路。 该电路在制造期间可以包括向掩埋电极和屏蔽层提供电压以防止来自极化场的损伤的结构。