发明申请
- 专利标题: METHODS FOR MAKING AND USING SPR MICROARRAYS
- 专利标题(中): 制备和使用SPR微量元素的方法
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申请号: US12330384申请日: 2008-12-08
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公开(公告)号: US20090093067A1公开(公告)日: 2009-04-09
- 发明人: Nicholas Adam Wolf , Danliang Jin , Anna Barklund , Raluca Dinu
- 申请人: Nicholas Adam Wolf , Danliang Jin , Anna Barklund , Raluca Dinu
- 申请人地址: US WA Bothell
- 专利权人: LUMERA CORPORATION
- 当前专利权人: LUMERA CORPORATION
- 当前专利权人地址: US WA Bothell
- 主分类号: G01N33/566
- IPC分类号: G01N33/566 ; B05D3/10 ; B05D7/24 ; B05D7/00 ; G01N33/00
摘要:
An article, process, and method for surface plasmon resonance plates are described. A substrate is covered with a thin metal film onto which a second thin metal film is deposited. The surface of the second thin metal film is converted to the metal oxide which is used to covalently bond organosilanes to the surface. Reactive organosilanes containing terminal bonding groups are arranged in a plurality of spots that are surrounded by inert organosilanes. Biomolecule attachment to the binding group is detected or measured from surface plasmon signals from the first thin metal film.
公开/授权文献
- US08094315B2 Methods for making and using SPR microarrays 公开/授权日:2012-01-10
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