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    Systems and methods for producing asynchronous neural responses to treat pain and/or other patient conditions
    1.
    发明授权
    Systems and methods for producing asynchronous neural responses to treat pain and/or other patient conditions 有权
    用于产生用于治疗疼痛和/或其他患者病症的异步神经反应的系统和方法

    公开(公告)号：US08849410B2

    公开(公告)日：2014-09-30

    申请号：US13857960

    申请日：2013-04-05

    申请人： Nevro Corporation

    发明人： Andre B. Walker ,  Zi-Ping Fang ,  Anthony V. Caparso

    IPC分类号： A61N1/00 ,  A61N1/05 ,  A61N1/36 ,  A61N1/372

    CPC分类号： A61N1/36171 ,  A61N1/0551 ,  A61N1/36071 ,  A61N1/37247

    摘要： Systems and methods for producing asynchronous neural responses to treat pain and/or other patient conditions are disclosed. A method in accordance with a particular embodiment includes selecting a target stimulation frequency that is above a threshold frequency, with the threshold frequency corresponding to a refractory period for neurons of a target sensory neural population. The method can further include producing a patient sensation of paresthesia by directing an electrical signal to multiple sensory neurons of the target sensory neural population at the stimulation frequency, with individual neurons of the sensory neural population completing corresponding individual refractory periods at different times, resulting in an asynchronous sensory neuron response to the electrical signal.

    摘要翻译： 公开了用于产生用于治疗疼痛和/或其他患者状况的异步神经反应的系统和方法。 根据特定实施例的方法包括选择阈值频率以上的目标刺激频率，阈值频率对应于目标感觉神经群体的神经元的不应期。 该方法可以进一步包括通过在刺激频率下将电信号引导到目标感觉神经群体的多个感觉神经元来产生感觉异常感觉，感觉神经群体的个体神经元在不同时间完成相应的单个不应期，导致 对电信号的异步感觉神经元响应。

    Multi-frequency neural treatments and associated systems and methods
    2.
    发明授权
    Multi-frequency neural treatments and associated systems and methods 有权
    多频神经治疗及相关系统及方法

    公开(公告)号：US08774926B2

    公开(公告)日：2014-07-08

    申请号：US13705045

    申请日：2012-12-04

    申请人： Nevro Corporation

    发明人： Konstantinos Alataris ,  Anthony V. Caparso ,  Brian J. Erickson ,  Zi-Ping Fang ,  Andre B. Walker

    IPC分类号： A61N1/00

    CPC分类号： A61N1/0551 ,  A61N1/36071 ,  A61N1/36171 ,  A61N1/3787 ,  G06F19/00

    摘要： Multi-frequency neural treatments and associated systems and methods are disclosed. A method in accordance with a particular embodiment includes at least reducing patient pain by applying a first electrical signal to a first target location of the patient's spinal cord region at a frequency in a first frequency range of up to about 1,500 Hz, and applying a second electrical signal to a second target location of the patient's spinal cord region at a frequency in a second frequency range of from about 2,500 Hz to about 100,000 Hz.

    摘要翻译： 公开了多频神经治疗及相关系统和方法。 根据特定实施例的方法包括至少通过以高达约1500Hz的第一频率范围的频率将第一电信号施加到患者脊髓区域的第一目标位置来减少患者疼痛，并且施加第二电信号 电信号以约2,500Hz至约100,000Hz的第二频率范围内的患者脊髓区域的第二目标位置。

    SYSTEMS AND METHODS FOR PRODUCING ASYNCHRONOUS NEURAL RESPONSES TO TREAT PAIN AND/OR OTHER PATIENT CONDITIONS
    5.
    发明申请
    SYSTEMS AND METHODS FOR PRODUCING ASYNCHRONOUS NEURAL RESPONSES TO TREAT PAIN AND/OR OTHER PATIENT CONDITIONS 有权
    用于产生异丙酚神经反应以治疗疼痛和/或其他患者病症的系统和方法

    公开(公告)号：US20150105839A1

    公开(公告)日：2015-04-16

    申请号：US14483061

    申请日：2014-09-10

    申请人： Nevro Corporation

    发明人： Andre B. Walker ,  Zi-Ping Fang ,  Anthony V. Caparso

    IPC分类号： A61N1/36

    CPC分类号： A61N1/36171 ,  A61N1/0551 ,  A61N1/36071 ,  A61N1/37247

    摘要： Systems and methods for producing asynchronous neural responses to treat pain and/or other patient conditions are disclosed. A method in accordance with a particular embodiment includes selecting a target stimulation frequency that is above a threshold frequency, with the threshold frequency corresponding to a refractory period for neurons of a target sensory neural population. The method can further include producing a patient sensation of paresthesia by directing an electrical signal to multiple sensory neurons of the target sensory neural population at the stimulation frequency, with individual neurons of the sensory neural population completing corresponding individual refractory periods at different times, resulting in an asynchronous sensory neuron response to the electrical signal.

    摘要翻译： 公开了用于产生用于治疗疼痛和/或其他患者状况的异步神经反应的系统和方法。 根据特定实施例的方法包括选择阈值频率以上的目标刺激频率，阈值频率对应于目标感觉神经群体的神经元的不应期。 该方法可以进一步包括通过在刺激频率下将电信号引导到目标感觉神经群体的多个感觉神经元来产生感觉异常感觉，感觉神经群体的个体神经元在不同时间完成相应的单个不应期，导致 对电信号的异步感觉神经元响应。

    Systems and methods for producing asynchronous neural responses to treat pain and/or other patient conditions
    6.
    发明授权
    Systems and methods for producing asynchronous neural responses to treat pain and/or other patient conditions 有权

    公开(公告)号：US10173065B2

    公开(公告)日：2019-01-08

    申请号：US15192914

    申请日：2016-06-24

    申请人： Nevro Corporation

    发明人： Andre B. Walker ,  Zi-Ping Fang ,  Anthony V. Caparso

    IPC分类号： A61N1/00 ,  A61N1/36 ,  A61N1/05 ,  A61N1/372

    摘要： Systems and methods for producing asynchronous neural responses to treat pain and/or other patient conditions are disclosed. A method in accordance with a particular embodiment includes selecting a target stimulation frequency that is above a threshold frequency, with the threshold frequency corresponding to a refractory period for neurons of a target sensory neural population. The method can further include producing a patient sensation of paresthesia by directing an electrical signal to multiple sensory neurons of the target sensory neural population at the stimulation frequency, with individual neurons of the sensory neural population completing corresponding individual refractory periods at different times, resulting in an asynchronous sensory neuron response to the electrical signal.

    Systems and methods for delivering neural therapy correlated with patient status
    8.
    发明授权
    Systems and methods for delivering neural therapy correlated with patient status 有权
    用于递送神经治疗的系统和方法与患者状态相关

    公开(公告)号：US09199083B2

    公开(公告)日：2015-12-01

    申请号：US13740917

    申请日：2013-01-14

    申请人： Nevro Corporation

    发明人： Anthony V. Caparso ,  Jon Parker ,  Andre B. Walker ,  Yougandh Chitre

    IPC分类号： A61N1/36 ,  A61N1/02 ,  G06F19/00 ,  A61N1/372

    CPC分类号： A61N1/36139 ,  A61N1/025 ,  A61N1/3605 ,  A61N1/36071 ,  A61N1/36132 ,  A61N1/37235 ,  G06F19/00 ,  G06F19/3418 ,  G06F19/3481 ,  G16H10/60 ,  G16H20/40 ,  G16H20/70

    摘要： Therapy systems for treating a patient are disclosed. Representative therapy systems include an implantable pulse generator, a signal delivery device electrically coupled to the pulse generator, and a remote control in electrical communication with the implantable pulse generator. The pulse generator can have a computer-readable medium containing instructions for performing a process that comprises collecting the patient status and stimulation parameter; analyzing the collected patient status and stimulation parameter; and establishing a preference baseline containing a preferred stimulation parameter corresponding to a particular patient status.

    摘要翻译： 公开了治疗患者的治疗系统。 代表性治疗系统包括可植入脉冲发生器，电耦合到脉冲发生器的信号传递装置以及与可植入脉冲发生器电通信的遥控器。 脉冲发生器可以具有包含用于执行包括收集患者状态和刺激参数的过程的指令的计算机可读介质; 分析收集的患者状况和刺激参数; 以及建立包含对应于特定患者状态的优选刺激参数的偏好基线。

    SYSTEMS AND METHODS FOR PRODUCING ASYNCHRONOUS NEURAL RESPONSES TO TREAT PAIN AND/OR OTHER PATIENT CONDITIONS
    10.
    发明申请
    SYSTEMS AND METHODS FOR PRODUCING ASYNCHRONOUS NEURAL RESPONSES TO TREAT PAIN AND/OR OTHER PATIENT CONDITIONS 有权
    用于产生异丙酚神经反应以治疗疼痛和/或其他患者病症的系统和方法

    公开(公告)号：US20140180359A1

    公开(公告)日：2014-06-26

    申请号：US13857960

    申请日：2013-04-05

    申请人： Nevro Corporation

    发明人： Andre B. Walker ,  Zi-Ping Fang ,  Anthony V. Caparso

    IPC分类号： A61N1/36

    CPC分类号： A61N1/36171 ,  A61N1/0551 ,  A61N1/36071 ,  A61N1/37247

    摘要： Systems and methods for producing asynchronous neural responses to treat pain and/or other patient conditions are disclosed. A method in accordance with a particular embodiment includes selecting a target stimulation frequency that is above a threshold frequency, with the threshold frequency corresponding to a refractory period for neurons of a target sensory neural population. The method can further include producing a patient sensation of paresthesia by directing an electrical signal to multiple sensory neurons of the target sensory neural population at the stimulation frequency, with individual neurons of the sensory neural population completing corresponding individual refractory periods at different times, resulting in an asynchronous sensory neuron response to the electrical signal.

    摘要翻译： 公开了用于产生用于治疗疼痛和/或其他患者状况的异步神经反应的系统和方法。 根据特定实施例的方法包括选择阈值频率以上的目标刺激频率，阈值频率对应于目标感觉神经群体的神经元的不应期。 该方法可以进一步包括通过在刺激频率下将电信号引导到目标感觉神经群体的多个感觉神经元来产生感觉异常感觉，感觉神经群体的个体神经元在不同时间完成相应的单个不应期，导致 对电信号的异步感觉神经元响应。