公开(公告)号：US11708338B2

公开(公告)日：2023-07-25

申请号：US17223989

申请日：2021-04-06

Applicant: Neuropore Therapies, Inc.

Inventor： Wolfgang J. Wrasidlo ,  Emily M. Stocking ,  Srinivasa Reddy Natala ,  Diana Luz Price

IPC: C07D249/12 ,  A61P25/28 ,  A61K9/10 ,  A61P3/00 ,  C07D243/10 ,  A61K31/18

CPC classification number: C07D249/12 ,  A61K9/10 ,  A61K31/18 ,  A61P3/00 ,  A61P25/28 ,  C07D243/10

Abstract: The present disclosure relates to substituted phenyl sulfonyl phenyl triazole thiones, pharmaceutical compositions containing them, and methods of using them.

公开(公告)号：US11008294B2

公开(公告)日：2021-05-18

申请号：US16663054

申请日：2019-10-24

Applicant: Neuropore Therapies, Inc.

Inventor： Wolfgang J. Wrasidlo ,  Emily M. Stocking ,  Srinivasa Reddy Natala ,  Diana Luz Price

IPC: C07D249/12 ,  A61P25/28 ,  A61K9/10 ,  A61P3/00 ,  C07D243/10 ,  A61K31/18

Abstract: The present disclosure relates to substituted phenyl sulfonyl phenyl triazole thiones, pharmaceutical compositions containing them, and methods of using them.

公开(公告)号：US11345713B2

公开(公告)日：2022-05-31

申请号：US17042034

申请日：2019-03-27

Applicant: Neuropore Therapies, inc.

Inventor： Srinivasa Reddy Natala ,  Wolfgang Wrasidlo

IPC: C07D495/04 ,  C07C47/57 ,  C07C47/575 ,  C07C49/255 ,  C07C223/06 ,  C07D207/04 ,  C07D211/32 ,  C07D213/30 ,  C07D215/06 ,  C07D231/12 ,  C07D295/104 ,  C07D295/112 ,  C07D311/58 ,  C07D319/18 ,  C07D403/12 ,  C07D413/12

Abstract: The present disclosure relates to compounds, pharmaceutical compositions comprising such compounds, and use of such compounds in methods of treatment or in medicaments for treatment of inflammatory diseases and certain neurological disorders that are related to inflammatory signaling processes, including but not limited to misfolded proteins.

公开(公告)号：US11299487B2

公开(公告)日：2022-04-12

申请号：US16830110

申请日：2020-03-25

Applicant: Neuropore Therapies, Inc.

Inventor： Srinivasa Reddy Natala ,  Wolfgang J. Wrasidlo ,  Emily M. Stocking

IPC: C07D417/10 ,  C07C235/56 ,  C07D207/06 ,  C07D211/10 ,  C07D231/12 ,  C07D265/30 ,  C07D265/36 ,  C07D401/06 ,  C07D401/10 ,  C07D403/10 ,  C07D403/14 ,  C07D405/04 ,  C07D405/14 ,  C07D409/10 ,  C07D413/06 ,  C07D413/10 ,  C07D413/14 ,  C07D471/08 ,  C07D487/08 ,  C07D498/02

Abstract: The present disclosure relates to substituted aryl and heteroaryl compounds, pharmaceutical compositions comprising such compounds, and use of such compounds in methods of treatment or in medicaments for treatment of inflammatory diseases and certain neurological disorders that are related to inflammatory signaling processes, including but not limited to misfolded proteins.