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公开(公告)号：US20170296507A1
公开(公告)日：2017-10-19
申请号：US15581558
申请日：2017-04-28
Applicant: Nestec S.A. , Beth Israel Deaconess Medical Center, Inc.
Inventor： Bruce Bistrian , Frederic Destaillats , Cristina Cruz-Hernandez , Fabiola Dionisi , Isabelle Masserey-Elmelegy , Manuel Oliveira , Julie Celine Moulin
IPC: A61K31/357 , A23L33/12 , A23K20/158 , A61K31/232 , A23L2/52
CPC classification number: A61K31/357 , A23K20/158 , A23L2/52 , A23L33/115 , A23L33/12 , A23V2002/00 , A61K31/202 , A61K31/232 , A23V2200/324 , A23V2250/187
Abstract: The present invention relates generally to the field of lipids and in particular aims at improving lipid absorption, for example under conditions of lipid maldigestion or malabsorption. One embodiment of the present invention relates to a composition comprising a sn-2 monoacylglycerol derivative, wherein the sn-1 and sn-3 positions are blocked by protective groups. The acyl group may be a fatty acid, for example one with anti-inflammatory properties.
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公开(公告)号：US09687462B2
公开(公告)日：2017-06-27
申请号：US15348334
申请日：2016-11-10
Applicant: NESTEC S.A. , Beth Israel Deaconess Medical Center, Inc.
Inventor： Bruce Bistrian , Frederic Destaillats , Cristina Cruz-Hernandez , Fabiola Dionisi , Isabelle Masserey-Elmelegy , Manuel Oliveira , Julie Celine Moulin
IPC: A01N43/02 , A61K31/335 , A61K31/232 , A61K31/357 , A23L2/52 , A23K20/158 , A23L33/12
CPC classification number: A61K31/357 , A23K20/158 , A23L2/52 , A23L33/115 , A23L33/12 , A23V2002/00 , A61K31/202 , A61K31/232 , A23V2200/324 , A23V2250/187
Abstract: The present invention relates generally to the field of lipids and in particular aims at improving lipid absorption, for example under conditions of lipid maldigestion or malabsorption. One embodiment of the present invention relates to a composition comprising a sn-2 monoacylglycerol derivative, wherein the sn-1 and sn-3 positions are blocked by protective groups. The acyl group may be a fatty acid, for example one with anti-inflammatory properties.
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公开(公告)号：US10039742B2
公开(公告)日：2018-08-07
申请号：US15581558
申请日：2017-04-28
Applicant: Nestec S.A. , Beth Israel Deaconess Medical Center, Inc.
Inventor： Bruce Bistrian , Frederic Destaillats , Cristina Cruz-Hernandez , Fabiola Dionisi , Isabelle Masserey-Elmelegy , Manuel Oliveira , Julie Celine Moulin
IPC: A01N43/02 , A61K31/335 , A61K31/357 , A61K31/232 , A23K20/158 , A23L2/52 , A23L33/12
Abstract: The present invention relates generally to the field of lipids and in particular aims at improving lipid absorption, for example under conditions of lipid maldigestion or malabsorption. One embodiment of the present invention relates to a composition comprising a sn-2 monoacylglycerol derivative, wherein the sn-1 and sn-3 positions are blocked by protective groups. The acyl group may be a fatty acid, for example one with anti-inflammatory properties.
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4.发明授权公开(公告)号：US08951550B2
公开(公告)日：2015-02-10
申请号：US14148197
申请日：2014-01-06
Inventor： Mark Puder , Bruce Bistrian
IPC: A61K47/00 , A23D9/013 , A23L1/30 , A61K31/202 , A61K31/23
CPC classification number: A23D9/013 , A23L33/12 , A23V2002/00 , A61K31/202 , A61K31/23 , A23V2250/1882 , A23V2250/1868 , A23V2250/187 , A23V2200/308 , A23V2200/324 , A23V2200/332
Abstract: Dietary formulations in the form of an oil emulsion providing total enteral or parenteral nutrition, or in the form of food oil suitable for oral administration is provided. The formulations include about 2-60% by calories of a C20 or longer omega-3 fatty acid and about 0.05% to 1% by calories of arachidonic acid, where the formulation provides less than 1% of total calories from linoleic acid and alpha-linolenic acid, and where the fatty acids provide 5-60% of the total calories of said dietary formulation. Methods for treatment of diseases and disorders using the dietary formulations are also provided.
Abstract translation: 提供了提供全肠内或胃肠外营养的油乳剂形式的膳食制剂，或以适于口服给药的食用油的形式。 制剂包括约2-60％的卡路里的C20或更长的ω-3脂肪酸和约0.05％至1％的卡路里花生四烯酸，其中该制剂提供低于亚油酸和α-亚油酸的总热量的1％ 亚麻酸，其中脂肪酸提供所述膳食制剂的总热量的5-60％。 还提供了使用膳食制剂治疗疾病和病症的方法。
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Patent Agency Ranking
公开(公告)号：US20150224079A1
公开(公告)日：2015-08-13
申请号：US14686340
申请日：2015-04-14
Applicant: NESTEC S.A.
Inventor： Bruce Bistrian , Frederic Destaillats , Cristina Cruz-Hernandez , Fabiola Dionisi , Isabelle Masserey-Elmelegy , Manuel Oliveira , Julie Celine Moulin
IPC: A61K31/357 , A61K31/232
CPC classification number: A61K31/357 , A23K20/158 , A23L2/52 , A23L33/115 , A23L33/12 , A23V2002/00 , A61K31/202 , A61K31/232 , A23V2200/324 , A23V2250/187
Abstract: The present invention relates generally to the field of lipids and in particular aims at improving lipid absorption, for example under conditions of lipid maldigestion or malabsorption. One embodiment of the present invention relates to a composition comprising a sn-2 monoacylglycerol derivative, wherein the sn-1 and sn-3 positions are blocked by protective groups. The acyl group may be a fatty acid, for example one with anti-inflammatory properties.
Abstract translation: 本发明一般涉及脂质领域，特别涉及改善脂质吸收，例如在脂质消化不良或吸收不良的条件下。 本发明的一个实施方案涉及包含Sn-2单酰基甘油衍生物的组合物，其中sn-1和sn-3位置被保护基团封闭。 酰基可以是脂肪酸，例如具有抗炎性质的脂肪酸。
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公开(公告)号：US09522132B2
公开(公告)日：2016-12-20
申请号：US14686340
申请日：2015-04-14
Applicant: NESTEC S.A.
Inventor： Bruce Bistrian , Frederic Destaillats , Cristina Cruz-Hernandez , Fabiola Dionisi , Isabelle Masserey-Elmelegy , Manuel Oliveira , Julie Celine Moulin
IPC: A01N43/02 , A61K31/335 , A61K31/357 , A23L1/30 , A61K31/202 , A61K31/232
CPC classification number: A61K31/357 , A23K20/158 , A23L2/52 , A23L33/115 , A23L33/12 , A23V2002/00 , A61K31/202 , A61K31/232 , A23V2200/324 , A23V2250/187
Abstract: The present invention relates generally to the field of lipids and in particular aims at improving lipid absorption, for example under conditions of lipid maldigestion or malabsorption. One embodiment of the present invention relates to a composition comprising a sn-2 monoacylglycerol derivative, wherein the sn-1 and sn-3 positions are blocked by protective groups. The acyl group may be a fatty acid, for example one with anti-inflammatory properties.
Abstract translation: 本发明一般涉及脂质领域，特别涉及改善脂质吸收，例如在脂质消化不良或吸收不良的条件下。 本发明的一个实施方案涉及包含Sn-2单酰基甘油衍生物的组合物，其中sn-1和sn-3位置被保护基团封闭。 酰基可以是脂肪酸，例如具有抗炎性质的脂肪酸。
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公开(公告)号：US09034917B2
公开(公告)日：2015-05-19
申请号：US14163163
申请日：2014-01-24
Applicant: Nestec S.A.
Inventor： Bruce Bistrian , Frederic Destaillats , Cristina Cruz-Hernandez , Fabiola Dionisi , Isabelle Masserey-Elmelegy , Manuel Oliveira , Julie Celine Moulin
IPC: A01N43/02 , A61K31/335 , A61K31/232 , A23L1/30 , A61K31/202 , A61K31/357
CPC classification number: A61K31/357 , A23K20/158 , A23L2/52 , A23L33/115 , A23L33/12 , A23V2002/00 , A61K31/202 , A61K31/232 , A23V2200/324 , A23V2250/187
Abstract: The present invention relates generally to the field of lipids and in particular aims at improving lipid absorption, for example under conditions of lipid maldigestion or malabsorption. One embodiment of the present invention relates to a composition comprising a sn-2 monoacylglycerol derivative, wherein the sn-1 and sn-3 positions are blocked by protective groups. The acyl group may be a fatty acid, for example one with anti-inflammatory properties.
Abstract translation: 本发明一般涉及脂质领域，特别涉及改善脂质吸收，例如在脂质消化不良或吸收不良的条件下。 本发明的一个实施方案涉及包含Sn-2单酰基甘油衍生物的组合物，其中sn-1和sn-3位置被保护基团封闭。 酰基可以是脂肪酸，例如具有抗炎性质的脂肪酸。
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公开(公告)号：US20140142169A1
公开(公告)日：2014-05-22
申请号：US14163163
申请日：2014-01-24
Applicant: NESTEC S.A.
Inventor： Bruce Bistrian , Frederic Destaillats , Cristina Cruz-Hernandez , Fabiola Dionisi , Isabelle Masserey-Elmelegy , Manuel Oliveira , Julie Celine Moulin
IPC: A61K31/232 , A61K31/357
CPC classification number: A61K31/357 , A23K20/158 , A23L2/52 , A23L33/115 , A23L33/12 , A23V2002/00 , A61K31/202 , A61K31/232 , A23V2200/324 , A23V2250/187
Abstract: The present invention relates generally to the field of lipids and in particular aims at improving lipid absorption, for example under conditions of lipid maldigestion or malabsorption. One embodiment of the present invention relates to a composition comprising a sn-2 monoacylglycerol derivative, wherein the sn-1 and sn-3 positions are blocked by protective groups. The acyl group may be a fatty acid, for example one with anti-inflammatory properties.
Abstract translation: 本发明一般涉及脂质领域，特别涉及改善脂质吸收，例如在脂质消化不良或吸收不良的条件下。 本发明的一个实施方案涉及包含Sn-2单酰基甘油衍生物的组合物，其中sn-1和sn-3位置被保护基团封闭。 酰基可以是脂肪酸，例如具有抗炎性质的脂肪酸。
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公开(公告)号：US20170056362A1
公开(公告)日：2017-03-02
申请号：US15348334
申请日：2016-11-10
Applicant: NESTEC S.A.
Inventor： Bruce Bistrian , Frederic Destaillats , Cristina Cruz-Hernandez , Fabiola Dionisi , Isabelle Masserey-Elmelegy , Manuel Oliveira , Julie Celine Moulin
IPC: A61K31/232 , A23L33/12 , A23K20/158 , A61K31/357 , A23L2/52
CPC classification number: A61K31/357 , A23K20/158 , A23L2/52 , A23L33/115 , A23L33/12 , A23V2002/00 , A61K31/202 , A61K31/232 , A23V2200/324 , A23V2250/187
Abstract: The present invention relates generally to the field of lipids and in particular aims at improving lipid absorption, for example under conditions of lipid maldigestion or malabsorption. One embodiment of the present invention relates to a composition comprising a sn-2 monoacylglycerol derivative, wherein the sn-1 and sn-3 positions are blocked by protective groups. The acyl group may be a fatty acid, for example one with anti-inflammatory properties.
Abstract translation: 本发明一般涉及脂质领域，特别涉及改善脂质吸收，例如在脂质消化不良或吸收不良的条件下。 本发明的一个实施方案涉及包含Sn-2单酰基甘油衍生物的组合物，其中sn-1和sn-3位置被保护基团封闭。 酰基可以是脂肪酸，例如具有抗炎性质的脂肪酸。
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