-
公开(公告)号：US11954888B2
公开(公告)日：2024-04-09
申请号：US17130294
申请日：2020-12-22
申请人： NIKON CORPORATION
发明人： Hiroaki Kii , Shinichi Takayama
CPC分类号： G06T7/90 , G06T7/0012 , G06V10/56 , G06V20/695 , G06V20/698 , G02B21/365 , G06T2207/10024 , G06T2207/10056 , G06T2207/30024
摘要： A device includes an image processing unit configured to calculate color information of at least one cell in a captured image and a determination unit configured to determine a cultured state of the cell on the basis of the color information calculated by the image processing unit.
-
公开(公告)号：US11068695B2
公开(公告)日：2021-07-20
申请号：US16124804
申请日：2018-09-07
申请人： NIKON CORPORATION
发明人： Hiroaki Kii , Yasujiro Kiyota , Takayuki Uozumi , Yoichi Yamazaki
摘要： An image processing device includes an image processing unit that performs image processing on an observed image in which a cell is imaged and an image processing method selector that is configured to determine an observed image processing method for analyzing the imaged cell on the basis of information of a processed image obtained through image processing of the image processing unit.
-
公开(公告)号：US11236755B2
公开(公告)日：2022-02-01
申请号：US16828100
申请日：2020-03-24
申请人： NIKON CORPORATION
发明人： Hiroaki Kii
IPC分类号： F01D25/00 , F04D29/02 , G01N21/64 , G02B21/36 , F04D29/053 , F04D29/058 , F04D29/059 , F16C3/02 , F16C35/04
摘要： A certain material irregularly expressed in an observation area is effectively observed. An observing apparatus includes a first observing unit performing a time lapse shooting of a predetermined observation area, a first discriminating unit discriminating whether or not a first material is expressed in the observation area based on an image obtained by the first observing unit, and a second observing unit starting a time lapse shooting relating to a part where the first material is expressed at a timing when the first material is expressed in the observation area, in which a shooting frequency of the time lapse shooting by the second observing unit is higher than a shooting frequency of the time lapse shooting by the first observing unit.
-
公开(公告)号：US10656136B2
公开(公告)日：2020-05-19
申请号：US15319336
申请日：2014-06-16
申请人： NIKON CORPORATION
发明人： Yasujiro Kiyota , Hiroaki Kii
IPC分类号： G01N33/483 , G01N15/06 , C12M1/36 , C12M1/34 , C12Q1/02 , G01N15/02 , G02B21/36 , G06K9/00 , G06T7/00 , G01N15/00 , G02B21/02
摘要： An observation apparatus includes: an area calculation unit that calculates a colony area based on an image in which a cell colony is captured; a cell number calculation unit that calculates, based on the image, the number of cells included in a target colony of which an area is calculated by the area calculation unit; and a density calculation unit that calculates, based on the area of the target colony calculated by the area calculation unit and the number of the cells included in the target colony calculated by the cell number calculation unit, a density of the cells included in the target colony.
-
公开(公告)号：US12054701B2
公开(公告)日：2024-08-06
申请号：US17224591
申请日：2021-04-07
发明人： Tomoro Dan , Hiroaki Kii , Takayuki Uozumi , Yoshiko Sato , Shinsuke Yoshida
摘要： A passage timing calculation device includes a processor and a memory encoded with instructions executed by the processor, wherein the instructions causing the processor to perform operations comprising calculating a time change in an area occupied by an extraction target region that is a region in which a striated pattern appears from a plurality of images of pluripotent stem cells captured at different times, detecting a change point of the time change in an area occupied by the extraction target region, and calculating a passage timing of the pluripotent stem cells on the basis of the change point.
-
公开(公告)号：US11222423B2
公开(公告)日：2022-01-11
申请号：US16125064
申请日：2018-09-07
发明人： Hiroaki Kii , Yasujiro Kiyota , Takayuki Uozumi , Miho Furue , Mika Suga
IPC分类号： G06K9/00 , G06T7/00 , C12M1/00 , C12Q1/68 , C12M1/36 , G01N15/14 , G02B21/36 , G16B45/00 , G01N21/64 , C12M1/34
摘要： An evaluation device includes a state determination unit which is configured to determine a state of cells which are an observation target under non-standard conditions on the basis of information acquired from an image of cells under standard conditions.
-
公开(公告)号：US11953498B2
公开(公告)日：2024-04-09
申请号：US17227967
申请日：2021-04-12
申请人： NIKON CORPORATION
发明人： Tomoro Dan , Hiroaki Kii , Takayuki Uozumi , Yasujiro Kiyota
CPC分类号： G01N33/5073 , C12M41/36 , C12Q1/04 , G06T7/0016 , G06T7/11 , G06T2207/10056 , G06T2207/30024 , G06T2207/30242
摘要： An image processing device includes: a processor; and a memory encoded with instructions executed by the processor, including: imaging pluripotent stem cells with time in a culture process and acquiring a plurality of images, extracting a colony region of the cells from the image, extracting a high luminance region on the basis of a group of pixels with larger luminance values than a standard value from among pixels constituting the image, extracting an extraction target region with relatively high contrast in the colony region on the basis of the colony and high luminance regions, and outputting the extraction target region as an extraction result, wherein as a relationship among the colony, high luminance, and extraction target regions, the colony region is formed, the high luminance region is then formed therein, and the extraction target region is then formed in the high luminance region in the culture process of the cells.
-
公开(公告)号：US11035845B2
公开(公告)日：2021-06-15
申请号：US16849529
申请日：2020-04-15
申请人： NIKON CORPORATION
发明人： Yasujiro Kiyota , Hiroaki Kii
IPC分类号： G01N33/483 , G01N15/06 , C12M1/36 , C12M1/34 , C12Q1/02 , G01N15/02 , G02B21/36 , G06K9/00 , G06T7/00 , G01N15/00 , G02B21/02
摘要： An observation apparatus includes: an area calculation unit that calculates a colony area based on an image in which a cell colony is captured; a cell number calculation unit that calculates, based on the image, the number of cells included in a target colony of which an area is calculated by the area calculation unit; and a density calculation unit that calculates, based on the area of the target colony calculated by the area calculation unit and the number of the cells included in the target colony calculated by the cell number calculation unit, a density of the cells included in the target colony.
-
公开(公告)号：US09779501B2
公开(公告)日：2017-10-03
申请号：US15008225
申请日：2016-01-27
申请人： NIKON CORPORATION
发明人： Hiroaki Kii , Chisako Iwamoto
CPC分类号： G06T7/0012 , G01N21/6458 , G06K9/00127 , G06K9/52 , G06K2009/4666 , G06T7/62 , G06T2207/10056 , G06T2207/20036 , G06T2207/30024
摘要： An image processing apparatus, a method, and a program for allowing cells to be quantitatively observed. A computer obtains a cell membrane image obtained by performing fluorescent observation on a cell membrane of a cell serving as a sample and a tricellular tight junction (tTJ) image obtained by performing fluorescent observation on a protein localized in a tTJ of the cell. The computer derives the size of area of a region of the cell by identifying the region of each cell from the cell membrane image, derives the size of area of the region of the protein localized in the cell from the tTJ image, and dividing the obtained size of area of the region of the protein by the size of area of the region of the cell, thus calculating an index of adhesion strength of the cells. The invention can be applied to an observation system.
-
公开(公告)号：US11941801B2
公开(公告)日：2024-03-26
申请号：US17128865
申请日：2020-12-21
申请人： NIKON CORPORATION
发明人： Hiroaki Kii , Shinichi Takayama
CPC分类号： G06T7/0012 , C12M41/46 , G01N15/0227 , G01N33/4833 , G06T7/60 , G06T7/70 , G01N2015/0065 , G06T2207/20092 , G06T2207/30024
摘要： A device includes: a distribution information acquiring part configured to acquire, based on an image in which a plurality of cells that are cultivated in a predetermined area are imaged, distribution information relating to a distribution in the predetermined area of the plurality of cells; and a determination part configured to determine a cultivated state of the plurality of cells based on the distribution information acquired by the distribution information acquiring part.
-
-
-
-
-
-
-
-
-
搜索结果
10 条记录 (耗时 0.014 秒)
