公开(公告)号：US20230090454A1

公开(公告)日：2023-03-23

申请号：US17933424

申请日：2022-09-19

申请人： NAUTILUS BIOTECHNOLOGY, INC.

发明人： Gregory KAPP ,  James Henry JOLY ,  James SHERMAN ,  Torri Elise RINKER ,  Raymond MAK

IPC分类号： G01N33/543 ,  C40B60/06 ,  G01N21/77 ,  B01J19/00 ,  G01N21/64 ,  G16B20/30

摘要： Methods and systems for identifying and/or quantifying polypeptide binding interactions of ligand-binding polypeptides are disclosed. Detailed methods include methods for identifying binding ligands of ligand-binding polypeptides and methods for assessing changes in binding behavior due to alterations of ligand-binding polypeptides. Detailed systems include array-based systems that permit detection of ligand binding interactions at single-analyte resolution.