公开(公告)号：US09956534B2

公开(公告)日：2018-05-01

申请号：US15676048

申请日：2017-08-14

申请人： Miltenyi Biotec GmbH

发明人： Dominik Hammerschmidt ,  Sven Ignatius ,  Martin Buscher ,  Ralf-Peter Peters

IPC分类号： B01F13/08 ,  B01F11/00 ,  B01F15/02 ,  B01F15/00 ,  C12M1/06 ,  G01N1/38 ,  G01N35/10

CPC分类号： B01F13/0854 ,  B01F11/0082 ,  B01F11/0091 ,  B01F13/08 ,  B01F13/0827 ,  B01F15/00032 ,  B01F15/0203 ,  B01F2215/0037 ,  C12M27/02 ,  G01N1/38 ,  G01N2001/386 ,  G01N2035/1058

摘要： The invention is related to a device for suspending particles in a fluid, wherein the mixing device includes a first magnet (1) rotating around a longitudinal axis (2), a mixing rod (4) attached to a mount (6), the mount including a second magnet (3), wherein the mount (6) moves in a substantially orthogonal motion to the longitudinal axis of the mixing rod (4) by the interaction of the rotating first magnet with the second magnet (3).

公开(公告)号：US20150328605A1

公开(公告)日：2015-11-19

申请号：US14705037

申请日：2015-05-06

申请人： Miltenyi Biotec GmbH

发明人： Dominik Hammerschmidt ,  Sven Ignatius ,  Martin Buscher ,  Ralf-Peter Peters

IPC分类号： B01F13/08

CPC分类号： B01F13/08 ,  B01F11/0082 ,  B01F11/0091 ,  B01F13/0827 ,  B01F15/00032 ,  B01F15/0203 ,  B01F2215/0037 ,  C12M27/02 ,  G01N1/38 ,  G01N2035/1058

摘要： The invention is related to a device for suspending particles in a fluid, wherein the mixing device includes a first magnet (1) rotating around a longitudinal axis (2), a mixing rod (4) attached to a mount (6), the mount including a second magnet (3), wherein the mount (6) moves in a substantially orthogonal motion to the longitudinal axis of the mixing rod (4) by the interaction of the rotating first magnet with the second magnet (3).

摘要翻译： 本发明涉及一种用于将颗粒悬浮在流体中的装置，其中混合装置包括围绕纵向轴线（2）旋转的第一磁体（1），连接到安装件（6）的混合杆（4） 包括第二磁体（3），其中所述安装件（6）通过所述旋转的第一磁体与所述第二磁体（3）的相互作用以基本正交的运动方式移动到所述混合杆（4）的纵向轴线。

公开(公告)号：US20180080876A1

公开(公告)日：2018-03-22

申请号：US15824632

申请日：2017-11-28

申请人： Miltenyi Biotec GmbH

发明人： Thomas Rockel ,  Stefan Miltenyi ,  Sven Ignatius ,  Jurgen Krieg

IPC分类号： G01N21/64 ,  G01N33/53 ,  G01N33/58

CPC分类号： G01N21/6428 ,  G01N21/6408 ,  G01N21/6452 ,  G01N21/6456 ,  G01N21/6486 ,  G01N33/5302 ,  G01N33/582 ,  G01N2021/6432 ,  G01N2201/061

摘要： Systems and methods are described for analyzing a plurality of biological samples with a plurality of fluorescent reagents in an automated fashion. The system may include two optical systems, a fluorescence imaging system and an optical quenching system. These two systems may be placed laterally adjacent to one another, and generally beneath one of the wells of sample-containing microtiter plate. The biological sample contained therein may be stained with a series of fluorescent reagents, with the fluorescence quenched between stainings. By precise positioning of the sample with respect to the imaging system, the sample may be imaged with a plurality of serially applied reagents.

公开(公告)号：US20170241911A1

公开(公告)日：2017-08-24

申请号：US15049368

申请日：2016-02-22

申请人： Miltenyi Biotec GmbH

发明人： Thomas Rockel ,  Stefan MILTENYI ,  Sven Ignatius ,  Jurgen Krieg

IPC分类号： G01N21/64 ,  G01N33/58 ,  G01N33/53

CPC分类号： G01N21/6428 ,  G01N21/6452 ,  G01N21/6456 ,  G01N21/6486 ,  G01N33/5302 ,  G01N33/582 ,  G01N2021/6432 ,  G01N2201/061

摘要： Systems and methods are described for analyzing a plurality of biological samples with a plurality of fluorescent reagents in an automated fashion. The system may include two optical systems, a fluorescence imaging system and an optical quenching system. These two systems may be placed laterally adjacent to one another, and generally beneath one of the wells of sample-containing microtiter plate. The biological sample contained therein may be stained with a series of fluorescent reagents, with the fluorescence quenched between stainings. By precise positioning of the sample with respect to the imaging system, the sample may be imaged with a plurality of serially applied reagents.

公开(公告)号：US11360025B2

公开(公告)日：2022-06-14

申请号：US15824632

申请日：2017-11-28

申请人： Miltenyi Biotec GmbH

发明人： Thomas Rockel ,  Stefan Miltenyi ,  Sven Ignatius ,  Jurgen Krieg

IPC分类号： G01N21/76 ,  G01N21/25 ,  G01N33/58 ,  G01N21/64 ,  G01N33/53

摘要： Systems and methods are described for analyzing a plurality of biological samples with a plurality of fluorescent reagents in an automated fashion. The system may include two optical systems, a fluorescence imaging system and an optical quenching system. These two systems may be placed laterally adjacent to one another, and generally beneath one of the wells of sample-containing microtiter plate. The biological sample contained therein may be stained with a series of fluorescent reagents, with the fluorescence quenched between stainings. By precise positioning of the sample with respect to the imaging system, the sample may be imaged with a plurality of serially applied reagents.

公开(公告)号：US20170361289A1

公开(公告)日：2017-12-21

申请号：US15676048

申请日：2017-08-14

申请人： Miltenyi Biotec GmbH

发明人： Dominik Hammerschmidt ,  Sven Ignatius ,  Martin Buscher ,  Ralf-Peter Peters

IPC分类号： B01F13/08 ,  B01F15/00 ,  C12M1/06 ,  B01F15/02 ,  B01F11/00 ,  G01N1/38

CPC分类号： B01F13/0854 ,  B01F11/0082 ,  B01F11/0091 ,  B01F13/08 ,  B01F13/0827 ,  B01F15/00032 ,  B01F15/0203 ,  B01F2215/0037 ,  C12M27/02 ,  G01N1/38 ,  G01N2001/386 ,  G01N2035/1058

摘要： The invention is related to a device for suspending particles in a fluid, wherein the mixing device includes a first magnet (1) rotating around a longitudinal axis (2), a mixing rod (4) attached to a mount (6), the mount including a second magnet (3), wherein the mount (6) moves in a substantially orthogonal motion to the longitudinal axis of the mixing rod (4) by the interaction of the rotating first magnet with the second magnet (3).