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62 条记录 (耗时 0.034 秒)

    USE OF RESISTIVE-PULSE SENSING WITH SUBMICROMETER PORES OR NANOPORES FOR THE DETECTION OF THE ASSEMBLY OF SUBMICROMETER OR NANOMETER SIZED OBJECTS
    1.
    发明申请
    USE OF RESISTIVE-PULSE SENSING WITH SUBMICROMETER PORES OR NANOPORES FOR THE DETECTION OF THE ASSEMBLY OF SUBMICROMETER OR NANOMETER SIZED OBJECTS 审中-公开
    使用电磁脉冲传感器与检测器或纳米器件进行检测，以检测分子或纳米尺寸对象的组装

    公开(公告)号：US20070202495A1

    公开(公告)日：2007-08-30

    申请号：US11671171

    申请日：2007-02-05

    申请人： Michael Mayer ,  Jeffrey Uram ,  Kevin Ke ,  Alan Hunt

    发明人： Michael Mayer ,  Jeffrey Uram ,  Kevin Ke ,  Alan Hunt

    IPC分类号： C12Q1/70 ,  C12Q1/68 ,  G01N33/53 ,  G01N33/554 ,  G01N33/569

    CPC分类号： G01N33/48721

    摘要： Methods and compositions for detecting the assembly of complexes include providing a solution where a first portion is separated from a second portion via a submicrometer pore, submicrometer tube or channel, nanopore, or nanotube or channel. One or more submicrometer or nanometer sized object(s) is added to the first portion of the solution. Due to molecular interactions, these objects assemble to form complexes consisting of two or more submicrometer or nanometer sized objects. Passage of a complex from the first portion of the solution through the submicrometer pore, submicrometer tube or channel, nanopore, or nanotube or channel to the second portion of the solution is detected using resistive pulse sensing. This sensing methodology may comprise detecting formation of complexes in real-time and/or may comprise detecting preassembled complexes.

    摘要翻译： 用于检测复合物组装的方法和组合物包括提供溶液，其中第一部分经由亚微米孔，亚微米管或通道，纳米孔或纳米管或通道从第二部分分离。 将一个或多个亚微米或纳米尺寸的物体加入溶液的第一部分。 由于分子相互作用，这些物体组装形成由两个或多个亚微米或纳米尺寸的物体组成的复合物。 使用电阻脉冲感测来检测复合物从溶液的第一部分通过亚微米孔，亚微米管或通道，纳米孔或纳米管或通道到解决方案的第二部分。 该感测方法可以包括实时检测复合物的形成和/或可以包括检测预组装的复合物。

    Remote radio head equipped with user equipment terminal capability
    2.
    发明授权
    Remote radio head equipped with user equipment terminal capability 有权

    公开(公告)号：US10772060B2

    公开(公告)日：2020-09-08

    申请号：US15492044

    申请日：2017-04-20

    申请人： Michael Mayer ,  Hassan Halabian

    发明人： Michael Mayer ,  Hassan Halabian

    IPC分类号： H04J3/06 ,  H04W56/00 ,  H04W88/02 ,  H04W88/08

    摘要： A remote radio head (RRH) of a distributed radio access network (RAN) is equipped with a co-located user equipment (UE). The UE can be a chipset integrated into the RRH, which is connected to other parts of the RAN via a fronthaul network. The UE can be used to relay information, such as management information to and/or from the RRH. Timing information obtained by the UE can be provided to the RRH and used as an indication of fronthaul latency. The RRH can then adjust its operation in response to the indication of fronthaul latency.

    SCREENING ASSAYS FOR INHIBITORS OF BETA AMYLOID PEPTIDE ION CHANNEL FORMATION
    6.
    发明申请
    SCREENING ASSAYS FOR INHIBITORS OF BETA AMYLOID PEPTIDE ION CHANNEL FORMATION 审中-公开
    β-淀粉样蛋白离子通道形成抑制剂筛选测定

    公开(公告)号：US20100178658A1

    公开(公告)日：2010-07-15

    申请号：US12602373

    申请日：2008-05-30

    申请人： Michael Mayer ,  Jerry Yang

    发明人： Michael Mayer ,  Jerry Yang

    IPC分类号： G01N33/567

    CPC分类号： G01N33/6896 ,  G01N2333/4709 ,  G01N2500/00 ,  G01N2800/2814

    摘要： Screening assays and methods of employing the screening assays designed to identify potential inhibitors of amyloidal neurodegenerative disease. The screening assays comprises providing a membrane construct disposed on a substrate and contacting the membrane construct with Aβ peptide capable of forming an Aβ peptide ion channel in the construct. The membrane construct is then contacted with a test compound. Aβ peptide ion channel activity is determined after the construct has incubated with the Aβ peptide in the presence and in the absence of the test compound. A reduction in the Aβ peptide ion channel activity of the membrane construct contacted with the test compound in comparison to a different membrane construct contacted with the same Aβ peptide in the absence of said test compound indicates that the test compound is an inhibitor of amyloidal neurodegenerative disease.

    摘要翻译： 筛选试验和采用筛选试验的方法，设计用于鉴定淀粉样变性神经变性疾病的潜在抑制剂。 筛选测定法包括提供设置在基质上并使膜构建体与A＆bgr接触的膜构建体; 能够形成A＆bgr的肽; 肽离子通道在构建体中。 然后将膜构建体与测试化合物接触。 A＆bgr 在构建体与A＆bgr孵育后测定肽离子通道活性; 肽在存在和不存在测试化合物的情况下。 减少A＆bgr; 与与相同A＆Bgr接触的不同膜构建体相比，膜构建体与测试化合物接触的肽离子通道活性; 在不存在所述测试化合物的情况下，肽表明测试化合物是淀粉样神经变性疾病的抑制剂。

    Method and Device for Converting Thermal Energy Into Mechanical Work
    7.
    发明申请
    Method and Device for Converting Thermal Energy Into Mechanical Work 审中-公开
    将热能转化为机械工作的方法和装置

    公开(公告)号：US20090229265A1

    公开(公告)日：2009-09-17

    申请号：US12227856

    申请日：2007-05-24

    申请人： Michael Mayer ,  Bernd Peter Pfeifer ,  Franz Peter Jegel ,  Steve Hargreaves

    发明人： Michael Mayer ,  Bernd Peter Pfeifer ,  Franz Peter Jegel ,  Steve Hargreaves

    IPC分类号： F01K27/00 ,  F01K25/00

    CPC分类号： F01K25/02 ,  F01K27/005

    摘要： The invention relates to a method for converting thermal energy into mechanical work. Said method comprises the following steps which are performed as a cycle: A liquid work medium is fed from a supply reservoir (1) to a work container (3); the work medium in the work container (3) is heated by a first heat exchanger (5); a sub-amount of the work medium flows from the work container (3) to a pneumatic-hydraulic-converter (8), a hydraulic medium from the pneumatic-hydraulic-converter (8) is compressed in a work machine (9) in order to convert the hydraulic work of the hydraulic medium into mechanical work; the work medium from the pneumatic-hydraulic-converter (8) is fed back into the supply reservoir (1) and the hydraulic medium is returned into the pneumatic-hydraulic-converter (8). The invention also relates to a device for carrying out said method.

    摘要翻译： 本发明涉及一种将热能转换为机械作业的方法。 所述方法包括作为循环执行的以下步骤：液体工作介质从供应储存器（1）进给到工作容器（3）; 工作容器（3）中的工作介质由第一热交换器（5）加热; 工作介质的分量从工作容器（3）流向气动 - 液压 - 转换器（8），来自气动 - 液压 - 转换器（8）的液压介质在工作机械（9）中被压缩 将液压介质的液压工作转换为机械作业; 来自气动 - 液压转换器（8）的工作介质被反馈到供应储存器（1）中，并且液压介质返回到气动 - 液压转换器（8）中。 本发明还涉及一种用于执行所述方法的装置。

    Apparatus for Treating Spinal Stenosis
    8.
    发明申请
    Apparatus for Treating Spinal Stenosis 有权
    用于治疗脊柱狭窄的装置

    公开(公告)号：US20090012528A1

    公开(公告)日：2009-01-08

    申请号：US11997880

    申请日：2006-08-03

    申请人： Felix Aschmann ,  Peter Senn ,  Michael Mayer ,  Paul Pavlov

    发明人： Felix Aschmann ,  Peter Senn ,  Michael Mayer ,  Paul Pavlov

    IPC分类号： A61B17/58 ,  A61F5/00 ,  B25B21/00

    CPC分类号： A61B17/7065 ,  A61B17/848 ,  A61B17/8897 ,  A61B90/39

    摘要： A device for treating spinal stenosis having an implant body structure sized and configured to be positioned between the spinous processes of two adjacent vertebrae. The device may have a body portion having a first end portion, a second end portion and a sleeve between the first and second end portions. The device may also have at least two retainers positioned in and extendable from the body portion. A mechanism positioned within the body portion may be used to move the retainers between a retracted position and a deployed position. When the retainers are in the deployed position, the retainers may be positioned around the spinous process of at least one of two adjacent vertebrae. A plurality of installation tools which may be used to install the device are also disclosed.

    摘要翻译： 一种用于治疗脊柱狭窄的装置，其具有植入物主体结构，其尺寸和构造被定位在两个相邻椎骨的棘突之间。 该装置可以具有在第一和第二端部之间具有第一端部，第二端部和套筒的主体部分。 该装置还可以具有定位在主体部分中并且可从本体部分延伸的至少两个保持器。 定位在主体部分内的机构可以用于在缩回位置和展开位置之间移动保持器。 当保持器处于展开位置时，保持器可以位于两个相邻椎骨中的至少一个椎骨的棘突周围。 还公开了可用于安装设备的多个安装工具。