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    DEFAULT CARBOHYDRATE CONSUMPTION COUNTS BASED ON POPULATION CARBOHYDRATE CONSUMPTION MODELS
    4.
    发明申请
    DEFAULT CARBOHYDRATE CONSUMPTION COUNTS BASED ON POPULATION CARBOHYDRATE CONSUMPTION MODELS 有权

    公开(公告)号：US20210398639A1

    公开(公告)日：2021-12-23

    申请号：US17336912

    申请日：2021-06-02

    Applicant: Medtronic MiniMed, Inc.

    Inventor： Anirban Roy ,  Benyamin Grosman ,  Louis J. Lintereur ,  Peter Onesti ,  Di Wu ,  Neha J. Parikh

    IPC: G16H20/17 ,  G16H20/60 ,  G06N3/08 ,  A61M5/172

    Abstract: The present disclosure relates to default carbohydrate consumption counts based on population carbohydrate consumption models. Aspects of the present disclosure relate to receiving, from a device, at least one characteristic of a person; accessing a population carbohydrate consumption model which relates the at least one characteristic with carbohydrate intake for a population; determining, based on applying the population carbohydrate consumption model to the at least one characteristic, at least one of: a preliminary carbohydrate count for the person or a default carbohydrate consumption count for the person; and causing delivery of insulin to the person based on communicating, to the device, at least one of: the preliminary carbohydrate count for the person or the default carbohydrate consumption count for the person.

    Personalized closed loop medication delivery system that utilizes a digital twin of the patient
    5.
    发明授权
    Personalized closed loop medication delivery system that utilizes a digital twin of the patient 有权

    公开(公告)号：US11158413B2

    公开(公告)日：2021-10-26

    申请号：US16386104

    申请日：2019-04-16

    Applicant: MEDTRONIC MINIMED, INC.

    Inventor： Benyamin Grosman ,  Di Wu ,  Louis J. Lintereur ,  Anirban Roy ,  Neha J. Parikh ,  Patrick E. Weydt ,  Ali Dianaty

    IPC: G16H20/17 ,  A61M5/172 ,  A61B5/00 ,  A61M5/142

    Abstract: A medical device system and related method of automatically adjusting parameters of an insulin delivery controller of an insulin infusion device are disclosed. The methodology obtains therapy-related data associated with operation of the insulin infusion device for a number of days in the past, including sensor glucose data associated with glucose levels of the user, and meal data associated with identified meals. The obtained therapy-related data is processed to generate a suitable pharmacokinetic/pharmacodynamic (PK/PD) model of the user, wherein the PK/PD model fits at least some of the sensor glucose data obtained for the user. The PK/PD model can be used to calculate at least one adjusted parameter of the insulin delivery controller, based on additional therapy-related data associated with further operation of the insulin infusion device. The insulin delivery controller can be instructed or controlled to adjust its settings in accordance with the model-calculated parameters.

    Insulin infusion device with configurable target blood glucose value for automatic basal insulin delivery operation
    7.
    发明授权
    Insulin infusion device with configurable target blood glucose value for automatic basal insulin delivery operation 有权

    公开(公告)号：US11097052B2

    公开(公告)日：2021-08-24

    申请号：US16419401

    申请日：2019-05-22

    Applicant: MEDTRONIC MINIMED, INC.

    Inventor： Louis J. Lintereur ,  Benyamin Grosman ,  Anirban Roy ,  Neha J. Parikh ,  Di Wu

    IPC: A61M5/172

    Abstract: An insulin infusion device and related operating methods are disclosed. An operating method maintains a configurable, patient-specific, target glucose setpoint for a user of the insulin infusion device, collects historical data associated with operation of the insulin infusion device, and calculates, from the historical data, a target glucose setpoint profile for the user of the insulin infusion device. A current target glucose setpoint value is automatically adjusted over time during a closed-loop operating mode of the insulin infusion device, in accordance with the calculated target glucose setpoint profile. In certain embodiments, the historical data is analyzed to determine a clinically preferred target glucose setpoint value for the user, which is stored for use during the closed-loop operating mode.

    Infusion devices and related meal bolus adjustment methods
    9.
    发明授权
    Infusion devices and related meal bolus adjustment methods 有权

    公开(公告)号：US10980942B2

    公开(公告)日：2021-04-20

    申请号：US16275289

    申请日：2019-02-13

    Applicant: MEDTRONIC MINIMED, INC.

    Inventor： Louis J. Lintereur ,  Anirban Roy ,  Benyamin Grosman ,  Patrick E. Weydt ,  Neha J. Parikh ,  Di Wu ,  Ali Dianaty

    IPC: A61M5/172 ,  A61B5/00 ,  G16H20/17 ,  G16H50/20 ,  A61B5/145

    Abstract: Medical devices and related systems and operating methods are provided. A method of operating an infusion device capable of delivering fluid influencing a physiological condition to a patient involves obtaining an event indication, such as a meal indication, determining an initial bolus amount based on the event indication, and determining predicted values for the physiological condition of the patient during a time window into the future based at least in part on the initial bolus amount. When the predicted values violate a threshold during the time window, the control system identifies an adjusted bolus amount that results in the predicted values for the physiological condition satisfying the threshold during the time window from within a search space defined by the initial bolus amount and operates an actuation arrangement of the infusion device to deliver the adjusted bolus amount of the fluid to the patient.

    PERSONALIZED CLOSED LOOP MEDICATION DELIVERY SYSTEM THAT UTILIZES A DIGITAL TWIN OF THE PATIENT
    10.
    发明申请
    PERSONALIZED CLOSED LOOP MEDICATION DELIVERY SYSTEM THAT UTILIZES A DIGITAL TWIN OF THE PATIENT 审中-公开

    公开(公告)号：US20190321553A1

    公开(公告)日：2019-10-24

    申请号：US16386104

    申请日：2019-04-16

    Applicant: MEDTRONIC MINIMED, INC.

    Inventor： Benyamin Grosman ,  Di Wu ,  Louis J. Lintereur ,  Anirban Roy ,  Neha J. Parikh ,  Patrick E. Weydt ,  Ali Dianaty

    IPC: A61M5/172 ,  G16H20/17

    Abstract: A medical device system and related method of automatically adjusting parameters of an insulin delivery controller of an insulin infusion device are disclosed. The methodology obtains therapy-related data associated with operation of the insulin infusion device for a number of days in the past, including sensor glucose data associated with glucose levels of the user, and meal data associated with identified meals. The obtained therapy-related data is processed to generate a suitable pharmacokinetic/pharmacodynamic (PK/PD) model of the user, wherein the PK/PD model fits at least some of the sensor glucose data obtained for the user. The PK/PD model can be used to calculate at least one adjusted parameter of the insulin delivery controller, based on additional therapy-related data associated with further operation of the insulin infusion device. The insulin delivery controller can be instructed or controlled to adjust its settings in accordance with the model-calculated parameters.

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