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1.发明申请公开(公告)号：US20180282495A1
公开(公告)日：2018-10-04
申请号：US15764942
申请日：2016-09-30
发明人： Elazer Edelman , Natalie Artzi , Hyun Seok Song , Yuji Yamamoto , Hiroki Yoshioka , Ken-ichiro Nakamoto
CPC分类号： C08J3/246 , A61K9/0024 , A61L27/18 , A61L27/20 , A61L27/38 , A61L27/3834 , A61L27/52 , A61L27/54 , A61L2400/06 , C08J2305/02 , C08J2343/02 , C08J2371/02 , C08L71/02
摘要： Provided herein are narrowly distributed multi-armed polyethylene glycol compounds, and hydrogels containing the same. Also provided are methods for treating, adhering, or sealing a biological tissue with hydrogels, and kits for making a hydrogel. Drug releasing compositions also are provided that include a narrowly distributed multi-armed polyethylene glycol compound.
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公开(公告)号：US10526457B2
公开(公告)日：2020-01-07
申请号：US15764942
申请日：2016-09-30
发明人： Elazer Edelman , Natalie Artzi , Hyun Seok Song , Yuji Yamamoto , Hiroki Yoshioka , Ken-ichiro Nakamoto
摘要： Provided herein are narrowly distributed multi-armed polyethylene glycol compounds, and hydrogels containing the same. Also provided are methods for treating, adhering, or sealing a biological tissue with hydrogels, and kits for making a hydrogel. Drug releasing compositions also are provided that include a narrowly distributed multi-armed polyethylene glycol compound.
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3.发明授权公开(公告)号：US10376162B2
公开(公告)日：2019-08-13
申请号：US15709080
申请日：2017-09-19
发明人： Elazer Edelman , Brian Chang , Noam Joesphy , Sonya Sanat Bhavsar
IPC分类号： A61B5/021 , A61B5/02 , A61B5/0215 , A61N1/362 , A61M1/10 , A61M1/12 , A61B5/0205 , A61B5/029 , A61B5/0456 , A61B5/00 , A61B5/024 , A61B5/026
摘要： The systems, devices, and methods presented herein use a heart pump to obtain measurements of cardiovascular function. The heart pumps described herein can operate in parallel with and unload the heart. The system can quantify the functioning of the native heart by measuring certain parameters/signals such as pressure or motor current, then calculate and display one or more metrics of cardiovascular function. These metrics, such as left ventricular end diastolic pressure (LVEDP), left ventricular pressure, and contractility, provide valuable information to a user regarding a patient's state of heart function and recovery.
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4.发明申请公开(公告)号：US20220167862A1
公开(公告)日：2022-06-02
申请号：US17518193
申请日：2021-11-03
发明人： Elazer Edelman , Brian Chang , Noam Josephy , Sonya Sanat Bhavsar
IPC分类号： A61B5/021 , A61B5/0205 , A61B5/0215 , A61B5/029 , A61B5/00 , A61B5/352 , A61M60/50 , A61M60/135 , A61B5/02
摘要： The systems, devices, and methods presented herein use a heart pump to obtain measurements of cardiovascular function. The heart pumps described herein can operate in parallel with and unload the heart. The system can quantify the functioning of the native heart by measuring certain parameters/signals such as pressure or motor current, then calculate and display one or more metrics of cardiovascular function. These metrics, such as left ventricular end diastolic pressure (LVEDP), left ventricular pressure, and contractility, provide valuable information to a user regarding a patient's state of heart function and recovery.
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5.发明授权公开(公告)号：US11197618B2
公开(公告)日：2021-12-14
申请号：US16455835
申请日：2019-06-28
发明人： Elazer Edelman , Brian Chang , Noam Joesphy , Sonya Sanat Bhavsar
IPC分类号： A61B5/021 , A61B5/02 , A61B5/0205 , A61B5/0215 , A61B5/029 , A61B5/00 , A61B5/352 , A61M60/50 , A61M60/135 , A61B5/024 , A61B5/026
摘要： The systems, devices, and methods presented herein use a heart pump to obtain measurements of cardiovascular function. The heart pumps described herein can operate in parallel with and unload the heart. The system can quantify the functioning of the native heart by measuring certain parameters/signals such as pressure or motor current, then calculate and display one or more metrics of cardiovascular function. These metrics, such as left ventricular end diastolic pressure (LVEDP), left ventricular pressure, and contractility, provide valuable information to a user regarding a patient's state of heart function and recovery.
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公开(公告)号：US20240189573A1
公开(公告)日：2024-06-13
申请号：US18533443
申请日：2023-12-08
发明人： Jerald Curran , Steven Keller , Elazer Edelman , Ahmad El Katerji
IPC分类号： A61M60/523 , A61M60/13 , A61M60/17 , A61M60/216 , A61M60/531 , A61M60/585 , G16H40/63
CPC分类号： A61M60/523 , A61M60/13 , A61M60/17 , A61M60/216 , A61M60/531 , A61M60/585 , G16H40/63 , A61M2230/30
摘要： Methods and apparatus for determining a contractile reserve of a heart of a patient are provided. The method includes controlling a heart pump to operate at a first speed, determining based on a motor current signal received from a motor when the heart pump is operating at the first speed, a first value for a cardiac contractility metric, controlling the heart pump to operate at a second speed, determining based, at least in part, on the motor current signal received from the motor when the heart pump is operating at the second speed, a second value for the cardiac contractility metric, determining a contractile reserve metric based, at least in part, on the first value and the second value of the cardiac contractility metric, and outputting an indication of the contractile reserve metric on a user interface associated with the heart pump.
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7.发明申请公开(公告)号：US20180078159A1
公开(公告)日：2018-03-22
申请号：US15709080
申请日：2017-09-19
发明人： Elazer Edelman , Brian Chang , Noam Joesphy , Sonya Sanat Bhavsar
IPC分类号： A61B5/021 , A61B5/02 , A61B5/0215
CPC分类号： A61B5/02141 , A61B5/02028 , A61B5/0205 , A61B5/0215 , A61B5/02158 , A61B5/02405 , A61B5/026 , A61B5/029 , A61B5/0456 , A61B5/4848 , A61B5/7275 , A61B2505/09 , A61M1/1086 , A61M1/125
摘要： The systems, devices, and methods presented herein use a heart pump to obtain measurements of cardiovascular function. The heart pumps described herein can operate in parallel with and unload the heart. The system can quantify the functioning of the native heart by measuring certain parameters/signals such as pressure or motor current, then calculate and display one or more metrics of cardiovascular function. These metrics, such as left ventricular end diastolic pressure (LVEDP), left ventricular pressure, and contractility, provide valuable information to a user regarding a patient's state of heart function and recovery.
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8.发明授权公开(公告)号：US11986274B2
公开(公告)日：2024-05-21
申请号：US17518193
申请日：2021-11-03
发明人： Elazer Edelman , Brian Chang , Noam Josephy , Sonya Sanat Bhavsar
IPC分类号： A61B5/021 , A61B5/00 , A61B5/02 , A61B5/0205 , A61B5/0215 , A61B5/029 , A61B5/352 , A61M60/178 , A61M60/216 , A61M60/422 , A61M60/531 , A61M60/554 , A61M60/857 , A61B5/024 , A61B5/026
CPC分类号： A61B5/02141 , A61B5/02028 , A61B5/0205 , A61B5/0215 , A61B5/02158 , A61B5/029 , A61B5/352 , A61B5/4848 , A61B5/7275 , A61M60/178 , A61M60/216 , A61M60/422 , A61M60/531 , A61M60/554 , A61M60/857 , A61B5/02405 , A61B5/026 , A61B2505/09
摘要： The systems, devices, and methods presented herein use a heart pump to obtain measurements of cardiovascular function. The heart pumps described herein can operate in parallel with and unload the heart. The system can quantify the functioning of the native heart by measuring certain parameters/signals such as pressure or motor current, then calculate and display one or more metrics of cardiovascular function. These metrics, such as left ventricular end diastolic pressure (LVEDP), left ventricular pressure, and contractility, provide valuable information to a user regarding a patient's state of heart function and recovery.
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9.发明申请公开(公告)号：US20200060559A1
公开(公告)日：2020-02-27
申请号：US16455835
申请日：2019-06-28
发明人： Elazer Edelman , Brian Chang , Noam Joesphy , Sonya Sanat Bhavsar
IPC分类号： A61B5/021 , A61M1/10 , A61M1/12 , A61B5/0205 , A61B5/0215 , A61B5/029 , A61B5/0456 , A61B5/00 , A61B5/02
摘要： The systems, devices, and methods presented herein use a heart pump to obtain measurements of cardiovascular function. The heart pumps described herein can operate in parallel with and unload the heart. The system can quantify the functioning of the native heart by measuring certain parameters/signals such as pressure or motor current, then calculate and display one or more metrics of cardiovascular function. These metrics, such as left ventricular end diastolic pressure (LVEDP), left ventricular pressure, and contractility, provide valuable information to a user regarding a patient's state of heart function and recovery.
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