公开(公告)号：US5962700A

公开(公告)日：1999-10-05

申请号：US11607

申请日：1998-02-12

申请人： Marc Heider ,  Thomas Ruhl ,  Jochem Henkelmann ,  Susanne Stutz ,  Thomas Preiss ,  Heinz Rutter ,  Martin Schafer ,  Arthur Hohn

发明人： Marc Heider ,  Thomas Ruhl ,  Jochem Henkelmann ,  Susanne Stutz ,  Thomas Preiss ,  Heinz Rutter ,  Martin Schafer ,  Arthur Hohn

IPC分类号： C07D307/33 ,  B01J31/20 ,  C07B61/00 ,  C07D307/58 ,  C07D315/00 ,  C07F7/08

CPC分类号： C07D315/00

摘要： A process for the preparation of butyrolactones of the formula I ##STR1## where the substituents R.sup.1 and R.sup.2 are hydrogen, alkyl or hydroxyalkyl groups, or aryl and trialkylsilyl groups, if appropriate carrying inert: substituents, is described in which an alkyne of the formula IIR.sup.1 --C.tbd.C--R.sup.2 IIwhere the substituents have the meanings indicated above, is reacted under reducing conditions at elevated pressure and elevated temperature with carbon monoxide CO and hydrogen in the presence of a transition metal catalyst or with carbon monoxide and water in the presence of a transition metal catalyst.

摘要翻译： PCT No.PCT / EP96 / 03472 Sec。 371日期1998年2月12日 102（e）日期1998年2月12日PCT 1996年8月6日PCT PCT。 公开号WO97 / 07111 日期1997年2月27日描述了制备式I的丁内酯的方法，其中取代基R 1和R 2是氢，烷基或羟基烷基，或芳基和三烷基甲硅烷基，如果适用的话带有惰性：取代基，其中描述了炔 其中取代基具有上述含义的式IIR1-C 3BOND C-R2II在还原条件下在升高的压力和升高的温度下与一氧化碳CO和氢在过渡金属催化剂或一氧化碳和水的存在下反应 过渡金属催化剂的存在。

公开(公告)号：US5723678A

公开(公告)日：1998-03-03

申请号：US631095

申请日：1996-04-12

申请人： Thomas Ruhl ,  Jochem Henkelmann ,  Marc Heider ,  Peter Hofmann

发明人： Thomas Ruhl ,  Jochem Henkelmann ,  Marc Heider ,  Peter Hofmann

IPC分类号： B01J31/24 ,  C07B61/00 ,  C07C45/68 ,  C07C45/69 ,  C07C47/222 ,  C07C47/232 ,  C07C49/207 ,  C07C49/217 ,  C07C67/347 ,  C07C69/606 ,  C07C69/612 ,  H04L25/03 ,  C07C45/45

CPC分类号： C07C67/347 ,  C07C45/69 ,  H04L25/03057

摘要： Acetylenic compounds of the general formula I R.sup.1 --C.tbd.C--CHR.sup.2 --CH.sub.2 --X I where the substituents have the following meanings: R.sup.1 hydrogen, unsubstituted or substituted alkyl or aryl; R.sup.2 hydrogen or C.sub.1 -C.sub.4 -alkyl; X CN; COOR.sup.3 where R.sup.3 is C.sub.1 -C.sub.6 -alkyl or benzyl; C(O)R.sup.4 where R.sup.4 is hydrogen or C.sub.1 -C.sub.4 -alkyl, are prepared by reacting an alkyne of the formula II R.sup.1 --C.tbd.C--H II with an .alpha.,.beta.-unsaturated compound of the formula III R.sup.2 HC.dbd.CH--X III in the presence of a homogeneous rhodium-phosphine catalyst, in a process wherein a catalyst with a bidentate or tridentate phosphine compound is used.

摘要翻译： 通式ⅠR1-C3BOC C-CHR2-CH2-XI的乙炔化合物，其中取代基具有下列含义：R 1氢，未取代或取代的烷基或芳基; R2氢或C1-C4-烷基; X CN; COOR 3，其中R 3是C 1 -C 6 - 烷基或苄基; 其中R 4是氢或C 1 -C 4 - 烷基的C（O）R 4是通过使式IIR 1 -C 3 3BOND C-HII的炔与式III的α，β-不饱和化合物反应来制备的。R2HC = CH-XIII 在均相铑 - 膦催化剂的存在下，在其中使用具有二齿或三齿膦化合物的催化剂的方法中。

公开(公告)号：US5710331A

公开(公告)日：1998-01-20

申请号：US548724

申请日：1995-10-26

申请人： Marc Heider ,  Thomas Ruhl ,  Jochem Henkelmann

发明人： Marc Heider ,  Thomas Ruhl ,  Jochem Henkelmann

IPC分类号： C07C231/04 ,  C07C231/08 ,  C07C233/02 ,  C07C233/03 ,  C07C233/58 ,  C07C233/65 ,  C07C233/05

CPC分类号： C07C231/08

摘要： Preparation of N-alkenyl carboxamides of the general formula I ##STR1## in which the radicals R.sup.1 to R.sup.4 independently stand for hydrogen or for aliphatic, cycloaliphatic, or aromatic radicals, which optionally carry inert substituents, wherein an amide of the general formula II ##STR2## in which the radical R.sup.1 has the above meaning, and a carbonyl compound of the general formula III ##STR3## in which the radicals R.sup.2 to R.sup.4 have the above meanings, are caused to react in the presence of a base, said reaction being either a) carried out in the presence of a carboxylic acid derivative of the general formula IV ##STR4## in which the radical R.sup.5 stands for hydrogen or an alkyl or aryl group and X is a halogen, alkoxy, or carboxylalkyl radical, or b) continued in the presence of a carboxylic acid derivative of the formula IV, and the amide of the formula I is isolated.

摘要翻译： 其中基团R 1至R 4独立地代表氢或用于任选地带有惰性取代基的脂族，脂环族或芳族基团的通式I（I）的N-烯基甲酰胺的制备，其中一般的酰胺 其中基团R 1具有上述含义的式II（II）和其中基团R 2至R 4具有上述含义的通式III（III）的羰基化合物进行反应 碱的存在，所述反应是a）在通式IV（IV）的羧酸衍生物存在下进行，其中基团R 5代表氢或烷基或芳基，X是 卤素，烷氧基或羧基烷基，或b）在式Ⅳ的羧酸衍生物存在下连续进行，分离式Ⅰ的酰胺。

公开(公告)号：US5639890A

公开(公告)日：1997-06-17

申请号：US705682

申请日：1996-08-29

申请人： Jochem Henkelmann ,  Marc Heider ,  Thomas Ruhl

发明人： Jochem Henkelmann ,  Marc Heider ,  Thomas Ruhl

IPC分类号： C07C269/06 ,  C07D263/22 ,  C07D263/14

CPC分类号： C07C269/06 ,  C07D263/22

摘要： N-Alkenylcarbamic esters of the general formula I ##STR1## where at least one of the R.sup.1 radicals is hydrogen and the second R.sup.1 radical is hydrogen or C.sub.1 -C.sub.4 --alkyl, the R.sup.2 radical is an aliphatic, cycloaliphatic, araliphatic or aromatic radical which can be linked to the R.sup.3 radical to form a 2- to 10-membered bridge, and the R.sup.3 radical is an aliphatic, cycloaliphatic or aromatic radical, from an alkenyl carboxylate of the general formula II ##STR2## where R.sup.1 has the abovementioned meaning, and R.sup.4 is hydrogen, an aliphatic, cycloaliphatic or aromatic radical, and a carbamic ester of the general formula III ##STR3## where the R.sup.2 and R.sup.3 radicals have the abovementioned meanings, are prepared by reacting the starting compounds in the presence of a base.

摘要翻译： 其中至少一个R 1基团是氢且第二个R 1基团是氢或C 1 -C 4 - 烷基，R 2基团是脂族，环脂族，芳脂族或芳族基团的通式I的N-烯丙基氨基甲酸酯 其可以连接到R 3基团以形成2-至10-元桥，并且R 3基团是脂肪族，脂环族或芳族基团，其通式II的烯基羧酸酯其中R1具有上述 并且R 4是氢，脂族，脂环族或芳族基团，和通式III的氨基甲酸酯，其中R 2和R 3基团具有上述含义，是通过使起始化合物在 一个基地

公开(公告)号：US5783697A

公开(公告)日：1998-07-21

申请号：US776107

申请日：1997-01-21

申请人： Marc Heider ,  Jochem Henkelmann ,  Michael Karcher ,  Thomas Ruhl

发明人： Marc Heider ,  Jochem Henkelmann ,  Michael Karcher ,  Thomas Ruhl

IPC分类号： C07B61/00 ,  C07C269/04 ,  C07C271/08 ,  C07C271/10 ,  C07C271/12 ,  C07C271/20 ,  C07D295/205 ,  C07D521/00 ,  C07D211/06

CPC分类号： C07D295/205 ,  C07C269/04 ,  C07C271/10 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08

摘要： Vinyl carbamate compounds are prepared by reacting appropriate secondary amines with carbon dioxide and acetylenically unsaturated compounds in the presence of a compound of a metal from the platinum group, in particular a ruthenium compound, with either one of the two process steps (a) and (b) or, preferably, both being carried out: (a) the acetylene compound is reinjected during the reaction; (b) the reaction is carried out in the presence of a tertiary amine.

摘要翻译： PCT No.PCT / EP95 / 02805 Sec。 371日期1997年1月21日 102（e）1997年1月21日PCT PCT 1995年7月18日PCT公布。 出版物WO93 / 02498 日期1996年2月1日乙烯基氨基甲酸酯化合物通过使适当的仲胺与二氧化碳和炔属不饱和化合物在铂族化合物，特别是钌化合物的存在下与两个工艺步骤之一 （a）和（b）或优选两者进行：（a）乙炔化合物在反应期间被再注入; （b）反应在叔胺的存在下进行。

公开(公告)号：US5739398A

公开(公告)日：1998-04-14

申请号：US675585

申请日：1996-07-03

申请人： Jochem Henkelmann ,  Marc Heider ,  Thomas Ruhl

发明人： Jochem Henkelmann ,  Marc Heider ,  Thomas Ruhl

IPC分类号： C07D239/10 ,  B01J31/02 ,  C07B61/00 ,  C07C273/02 ,  C07C273/18 ,  C07C275/20

CPC分类号： C07C273/1863

摘要： A process for preparing N-alkenylureas of the general formula I ##STR1## where R.sup.1 and R.sup.2 are hydrogen, C.sub.1 - to C.sub.40 -alkyl, C.sub.2 - to C.sub.40 -alkenyl, C.sub.3 - to C.sub.20 -cycloalkyl, C.sub.4 - to C.sub.20 -alkylcyc1oalkyl, C.sub.4 - to C.sub.20 -cycloalkylalkyl, aryl, C.sub.7 - to C.sub.20 -alkylaryl or C.sub.7 - to C.sub.20 -aralkyl, or aryl, C.sub.7 - to C.sub.20 -alkylaryl or C.sub.7 - to C.sub.20 -aralkyl which are mono- to pentasubstituted by C.sub.1 - to C.sub.8 -alkyl, C.sub.1 - to C.sub.8 -alkoxy or halogen, together are a C.sub.2 - to C.sub.10 -alkylene chain which is unsubstituted or mono- to hexasubstituted by C.sub.1 - to C.sub.8 -alkyl, and R.sup.3 and R.sup.4 are hydrogen or C.sub.1 - to C.sub.8 -alkyl, by reaction of ureas of the general formula II ##STR2## where R.sup.1 and R.sup.2 have the abovementioned meanings, with an alkenyl carboxylate of the general formula III ##STR3## where R.sup.3 and R.sup.4 have the abovementioned meanings and R.sup.5 is hydrogen, C.sub.1 - to C.sub.40 -alkyl, C.sub.3 - to C.sub.20 -cycloalkyl, C.sub.4 - to C.sub.20 -alkylcycloalkyl, aryl, C.sub.7 - to C.sub.20 -alkylaryl, C.sub.7 - to C.sub.20 -aralkyl, or aryl or C.sub.7 - to C.sub.20 -aralkyl which is mono- to trisubstituted by C.sub.1 - to C.sub.8 -alkyl, at from 0.degree. to 180.degree. C. and from 0.01 to 10 bar, by carrying out the reaction in the presence of a base is described.

摘要翻译： 制备通式I（I）的N-烯基脲的方法，其中R 1和R 2是氢，C 1至C 40烷基，C 2至C 40链烯基，C 3 -C 20环烷基，C 4 -C 20 - 烷基环烷基，C 4 -C 20 - 环烷基烷基，芳基，C 7 -C 20 - 烷基芳基或C 7 -C 20 - 芳烷基，或被C 1 - 单取代成五取代的芳基，C 7 -C 20 - 烷基芳基或C 7 -C 20 - 芳烷基 -C 8 - 烷基，C 1 -C 8 - 烷氧基或卤素，一起是未被取代或被C 1〜C 8 - 烷基单取代或六取代的C 2〜C 10 - 亚烷基链，R 3和R 4是氢或C 1〜 通过其中R1和R2具有上述含义的通式II的脲（II）与通式III的烯基羧酸酯（III）的反应，其中R 3和R 4具有 R 5是氢，C 1 -C 40 - 烷基，C 3 -C 20 - 环烷基，C 4 -C 20 - 烷基环烷基，芳基，C 7 -C 20烷基芳基，C 7 -C 20 - 芳烷基或芳基或C 7 - 被单 - 三取代的C 20 - 芳烷基 描述了通过在碱的存在下进行反应的0至180℃和0.01至10巴的C 1 -C 8烷基。

公开(公告)号：US5654478A

公开(公告)日：1997-08-05

申请号：US513739

申请日：1995-08-10

申请人： Thomas Ruhl ,  Jochem Henkelmann ,  Marc Heider ,  Bernd Fiechter

发明人： Thomas Ruhl ,  Jochem Henkelmann ,  Marc Heider ,  Bernd Fiechter

IPC分类号： C07C231/14 ,  C07C231/08 ,  C07C233/03 ,  C07C233/04 ,  C07C233/58 ,  C07C233/65

CPC分类号： C07C231/08

摘要： N-Alkenylcarboxamides of the formula I ##STR1## where at least one of the radicals R.sup.1 is hydrogen, the second radical R.sup.1 is hydrogen or C.sub.1 -C.sub.4 -alkyl and R.sup.2 is hydrogen or an aliphatic, cycloaliphatic or aromatic radical, are prepared by reacting an alkenyl carboxylate of the formula II ##STR2## where R.sup.1 has the abovementioned meanings and R.sup.3 is hydrogen or an aliphatic, cycloaliphatic or aromatic radical, and a carboxamide of the general formula III ##STR3## where R.sup.2 has the abovementioned meanings, in the presence of a base.

摘要翻译： 其中至少一个基团R 1为氢，第二基团R 1为氢或C 1 -C 4 - 烷基且R 2为氢或脂族，脂环族或芳族基团的式I的N-烯基甲酰胺通过 使式II其中R 1具有上述含义并且R 3是氢或脂族，脂环族或芳族基团的式II的烯基羧酸酯和具有上述含义的通式III的羧酰胺反应， 在一个基地的存在。

公开(公告)号：US5603813A

公开(公告)日：1997-02-18

申请号：US510568

申请日：1995-08-02

申请人： Thomas Ruhl ,  Marc Heider ,  Jochem Henkelmann ,  Ralf-Thomas Rahn ,  Harald Rust

发明人： Thomas Ruhl ,  Marc Heider ,  Jochem Henkelmann ,  Ralf-Thomas Rahn ,  Harald Rust

IPC分类号： C07C67/54 ,  C07C69/07 ,  B01D3/00 ,  C07C51/44

CPC分类号： C07C67/54

摘要： Vinyl formate containing formic acid, acetaldehyde and water following synthesis is separated from formic acid and water in a first distillation stage and from acetaldehyde in a second stage to give pure vinyl formate.

摘要翻译： 合成后含有甲酸，乙醛和水的乙酸甲酯在第一蒸馏阶段从甲酸和水中分离，并在第二阶段从乙醛中分离，得到纯的甲酸乙烯酯。

公开(公告)号：US5723685A

公开(公告)日：1998-03-03

申请号：US548739

申请日：1995-10-26

申请人： Marc Heider ,  Thomas Ruhl ,  Herbert Helfert ,  Martin Schmidt-Radde ,  Jochem Henkelmann

发明人： Marc Heider ,  Thomas Ruhl ,  Herbert Helfert ,  Martin Schmidt-Radde ,  Jochem Henkelmann

IPC分类号： B01J23/02 ,  B01J31/02 ,  B01J31/12 ,  C07B61/00 ,  C07C41/06 ,  C07C41/08 ,  C07C43/178 ,  C07C41/00

CPC分类号： C07C41/08 ,  C07C41/54

摘要： The preparation of monovinyl ethers of the general formula I ##STR1## in which A stands for a chemical bond or for a methylene or ethylene group, the radicals R.sup.1 and R.sup.2 independently stand for hydrogen, alkyl, cycloalkyl, or aryl groups or R.sup.1 and R.sup.2 together form a C.sub.3 -C.sub.5 alkylene bridging member, by the reaction of a diol of the general formula II ##STR2## in which the variables have the above meanings, with acetylene in the presence of a base, in which the reaction is carried out at 150.degree.-250.degree. C. under an acetylene partial pressure of 5-25 bar until 40-80% of the diol has been converted, at which point the reaction is stopped and the monovinyl ether of the formula I is isolated.

摘要翻译： 制备通式I的单乙烯基醚（I）其中A代表化学键或亚甲基或亚乙基，基团R 1和R 2分别代表氢，烷基，环烷基或芳基或 R 1和R 2一起形成C 3 -C 5亚烷基桥连体，通过其中变量具有上述含义的通式II的二醇（II）与乙炔在碱的存在下反应，其中 反应在150-250℃，乙炔分压为5-25巴下进行，直到二醇的40-80％转化为止，此时反应停止，式I的单乙烯基醚 是孤立的

公开(公告)号：US5646293A

公开(公告)日：1997-07-08

申请号：US675588

申请日：1996-07-03

申请人： Jochem Henkelmann ,  Marc Heider ,  Thomas Ruhl

发明人： Jochem Henkelmann ,  Marc Heider ,  Thomas Ruhl

IPC分类号： B01J31/02 ,  C07B61/00 ,  C07D233/56 ,  C07D233/58 ,  C07D235/06 ,  C07D249/08 ,  C07D521/00 ,  C07D235/08 ,  C07D235/18

CPC分类号： C07D235/06 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08

摘要： A process for preparing N-alkenylazoles of the general formula I ##STR1## where X is CH--R.sup.6 or nitrogen,R.sup.1 and R.sup.2 are hydrogen or C.sub.1 - to C.sub.8 -alkyl,R.sup.3,R.sup.4,R.sup.5 and R.sup.6 are hydrogen, C.sub.1 - to C.sub.40 -alkyl, C.sub.2 - to C.sub.40 -alkenyl, C.sub.3 - to C.sub.20 -cycloalkyl, C.sub.4 - to C.sub.20 -alkylcycloalkyl, C.sub.4 - to C.sub.20 -cycloalkylalkyl, aryl, C.sub.7 - to C.sub.20 -alkylaryl or C.sub.7 - to C.sub.20 -aralkyl, or aryl, C.sub.7 - to C.sub.20 -alkylaryl or C.sub.7 - to C.sub.20 -aralkyl which are mono- to pentasubstituted by C.sub.1 - to C.sub.8 -alkyl, C.sub.1 - to C.sub.8 -alkoxy or halogen, or R.sup.3 and R.sup.4 or R.sup.4 and R.sup.5 or R.sup.5 and R.sup.6 together are a C.sub.2 - to C.sub.10 -alkylene chain which is unsubstituted or mono- to hexasubstituted by C.sub.1 - to C.sub.8 -alkylby reaction of azoles of the general formula II ##STR2## where X, R.sup.3, R.sup.4 and R.sup.5 have the abovementioned meanings, with an alkenyl carboxylate of the general formula III ##STR3## where R.sup.1 and R.sup.2 have the abovementioned meanings and R.sup.7 is hydrogen, C.sub.1 - to C.sub.40 -alkyl, C.sub.3 - to C.sub.20 -cycloalkyl, C.sub.4 - to C.sub.20 -alkylcycloalkyl, aryl, C.sub.7 - to C.sub.20 -alkylaryl, C.sub.7 - to C.sub.20 -aralkyl, or aryl or C.sub.7 - to C.sub.20 -aralkyl which is mono- to trisubstituted by C.sub.1 - to C.sub.8 -alkyl, at from 0.degree. to 180.degree. C. and from 0.01 to 10 bar, which comprises carrying out the reaction in the presence of a base and of a quaternary salt, is described.

摘要翻译： 制备通式I（I）的N-烯基唑的方法，其中X是CH-R6或氮，R1和R2是氢或C1-至C8-烷基，R3，R4，R5和R6是氢， C 1至C 40 - 烷基，C 2至C 40 - 烯基，C 3 -C 20 - 环烷基，C 4至C 20 - 烷基环烷基，C 4 -C 20 - 环烷基烷基，芳基，C 7 -C 20烷基芳基或C 7 -C 20 - 芳烷基 ，或被C 1〜C 8 - 烷基，C 1 -C 8 - 烷氧基或卤素单 - 五取代的芳基，C 7〜C 20 - 烷基芳基或C 7〜C 20 - 芳烷基，或者R 3和R 4或R 4和R 5或R 5 和R6一起是C2至C10亚烷基链，其未被取代或被C 1 -C 8 - 烷基单取代或被六取代的通式II（II）的唑类，其中X，R 3，R 4和R 5 具有上述含义，具有通式III（III）的烯基羧酸酯，其中R 1和R 2具有上述含义，并且R 7是氢，C 1至C 40烷基，C 3 -C 20环烷基，C 4至 C20-烷基环烷基，芳基，C7-至C20-烷基芳基，C7-至C20-芳基 烷基或芳基或被C 1 -C 8烷基单取代三取代的C 7 -C 20 - 芳烷基，其中0至180℃和0.01至10巴，其包括在存在下进行反应 的碱和季盐。