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公开(公告)号：US20210231499A1
公开(公告)日：2021-07-29
申请号：US17054157
申请日：2020-03-25
Inventor： Quaid Vohra , Celestin Zemtsop , Mark Watson
Abstract: A multi-dispersive spectrometer is provided in which the spectrometer comprises an an optical system configured to direct an excitation signal from an excitation light source toward a sample, receive a spectroscopy signal from the sample, and direct the spectroscopy signal toward the detector. The optical system comprises a movable optical component adapted to move the spectroscopy signal relative to at least one sensor of the detector and the detector is adapted to detect a plurality of discrete shifted spectroscopy signals. A method of obtaining a Raman spectrum from a sample is also provided. The method comprises directing an excitation signal from an excitation light source toward a sample; receiving a spectroscopy signal from the sample; and directing the spectroscopy signal toward a detector, wherein the spectroscopy signal is moved relative to at least one sensor of the detector to provide a plurality of discrete shifted spectroscopy signals.
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公开(公告)号：US20200256724A1
公开(公告)日：2020-08-13
申请号：US16681192
申请日：2019-11-12
Inventor： Mark Watson , Shane Buller , Keith Carron
Abstract: A spectrometer is provided. In one implementation, for example, a spectrometer comprises an excitation source, a focusing lens, a movable minor, and an actuator assembly. The focusing lens is adapted to focus an incident beam from the excitation source. The actuator assembly is adapted to control the movable minor to move a focused incident beam across a surface of the sample.
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公开(公告)号：US11441948B2
公开(公告)日：2022-09-13
申请号：US17054157
申请日：2020-03-25
Applicant: MKS TECHNOLOGY, INC.
Inventor： Quaid Vohra , Celestin Zemtsop , Mark Watson
Abstract: A multi-dispersive spectrometer is provided in which the spectrometer comprises an optical system configured to direct an excitation signal from an excitation light source toward a sample, receive a spectroscopy signal from the sample, and direct the spectroscopy signal toward the detector. The optical system comprises a movable optical component adapted to move the spectroscopy signal relative to at least one sensor of the detector and the detector is adapted to detect a plurality of discrete shifted spectroscopy signals. A method of obtaining a Raman spectrum from a sample is also provided. The method comprises directing an excitation signal from an excitation light source toward a sample; receiving a spectroscopy signal from the sample; and directing the spectroscopy signal toward a detector, wherein the spectroscopy signal is moved relative to at least one sensor of the detector to provide a plurality of discrete shifted spectroscopy signals.
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公开(公告)号：US20200348179A1
公开(公告)日：2020-11-05
申请号：US16728841
申请日：2019-12-27
Inventor： Keith Carron , Shane Buller , Mark Watson
IPC: G01J3/44 , G01N33/536 , G01N21/65 , G01N33/543 , G01J3/06
Abstract: A spectroscopic assay is provided. The assay comprises: a motive particle configured to move within a solution, the motive particle comprising a first analyte binding reagent for selectively binding to a target analyte; and a spectroscopic reporter particle configured to provide a predetermined spectroscopic signal in response to being interrogated by a spectrometer, the spectroscopic reporter particle comprising a second analyte binding reagent for selectively binding to the target analyte, wherein the motive particle and the spectroscopic reporter particle are configured to provide a sandwich assay in the presence of the target analyte via the first and second analyte binding reagents.
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