公开(公告)号：US3697529A

公开(公告)日：1972-10-10

申请号：US3697529D

申请日：1971-01-28

Applicant: MCNEILAB INC

Inventor： PLOSTNIEKS JANIS

IPC: C07D211/60 ,  C07D211/78 ,  C07D498/04 ,  C07D29/24

CPC classification number: C07D211/60 ,  C07D211/78

Abstract: The compounds are of the class of aralkyl penta- and hexamethylenimines which are useful as anti-arrhythmic agents; and to certain intermediates useful in the syntheses of such methylenimines.

Abstract translation: 这些化合物是可用作抗心律不齐剂的芳烷基五和六亚甲基亚胺类; 以及可用于合成这种亚甲基亚胺的某些中间体。

公开(公告)号：US3637659A

公开(公告)日：1972-01-25

申请号：US3637659D

申请日：1969-02-17

Applicant: MCNEILAB INC

Inventor： PLOSTNIEKS JANIS

IPC: C07D211/22 ,  C07D211/60 ,  C07D211/78 ,  C07D29/16 ,  C07D29/24 ,  C07D41/04

CPC classification number: C07D211/60 ,  C07D211/22 ,  C07D211/78 ,  Y10S514/821

Abstract: THE COMPOUNDS ARE OF THE CLASS OF ARALKYL PENTA- AND HEXAMETHYLENIMINES WHICH ARE USEFUL AS ANTI-ARRHYTHMIC AGENTS; AND TO CERTAIN INTERMEDIATES USEFUL IN THE SYNTHESES OF SUCH METHYLENIMINES.

公开(公告)号：US3493570A

公开(公告)日：1970-02-03

申请号：US3493570D

申请日：1967-03-30

Applicant: MCNEILAB INC

Inventor： PLOSTNIEKS JANIS

IPC: C07D215/22 ,  C07D215/227 ,  C07D215/38 ,  C07D33/34 ,  A61K27/00 ,  C07D33/18

CPC classification number: C07D215/227 ,  C07D215/38

公开(公告)号：US3435033A

公开(公告)日：1969-03-25

申请号：US3435033D

申请日：1967-05-02

Applicant: MCNEILAB INC

Inventor： PLOSTNIEKS JANIS

IPC: C07D471/04 ,  C07D498/20 ,  C07D87/20 ,  C07D29/20 ,  C07D29/24

CPC classification number: C07D471/04

公开(公告)号：US3706749A

公开(公告)日：1972-12-19

申请号：US3706749D

申请日：1970-03-27

Applicant: MCNEILAB INC

Inventor： PLOSTNIEKS JANIS

IPC: C07D215/22 ,  C07D215/227 ,  C07D33/46

CPC classification number: C07D215/227

Abstract: THE COMPOUNDS HEREIN ARE 3,4-DIHYDRO-4-METHYL-4PHENYL-6-CHLORO-CARBOSTYRIL DERIVATIVES, USEFUL FOR THEIR VARIOUS PHARMACOLOGICAL ACTIVITIES, SUCH AS ANTI-INFLAMMATORY, HYPOTENSIVE AND CENTRAL NERVOUS SYSTEM DEPRESSANT ACTIVITIES. ALSO INCLUDED HEREIN IS 4''-CHLORO-B-METHYL-CINNAMANILIDE, USEFUL IN THE SYNTHESIS OF THE SUBJECT CARBOSTYRILS.

公开(公告)号：US3703522A

公开(公告)日：1972-11-21

申请号：US3703522D

申请日：1970-03-27

Applicant: MCNEILAB INC

Inventor： PLOSTNIEKS JANIS

IPC: C07D215/22 ,  C07D215/227 ,  C07D33/52

CPC classification number: C07D215/227

Abstract: THE COMPOUNDS HEREIN ARE 3,4-DIHYDRO-4-METHYL-4PHENYL-6-CHLORO-CARBOSTYRIL DERIVATIVES, USEFUL FOR THEIR VARIOUS PHARMACOLOGICAL ACTIVITIES, SUCH AS ANTI-INFLAMMATORY, HYPOTENSIVE AND CENTRAL NERVOUS SYSTEM DEPRESSANT ACTIVITIES. ALSO INCLUDED HEREIN IS 4''-CHLORO-B-METHYLCINNAMANILIDE, USEFUL IN THE SYNTHESIS OF THE SUBJECT CARBOSTYRILS.

公开(公告)号：US3687958A

公开(公告)日：1972-08-29

申请号：US3687958D

申请日：1971-01-28

Applicant: MCNEILAB INC

Inventor： PLOSTNIEKS JANIS

IPC: C07D498/04 ,  C07D29/24

CPC classification number: C07D498/04

Abstract: The compounds are of the class of aralkyl penta- and hexamethylenimines which are useful as anti-arrhythmic agents; and to certain intermediates useful in the syntheses of such methylenimines.

Abstract translation: 这些化合物是可用作抗心律不齐剂的芳族五烷基和六亚甲基亚胺类; 以及可用于合成这种亚甲基亚胺的某些中间体。

公开(公告)号：US3692773A

公开(公告)日：1972-09-19

申请号：US3692773D

申请日：1971-01-28

Applicant: MCNEILAB INC

Inventor： PLOSTNIEKS JANIS

IPC: C07D211/22 ,  C07D227/04 ,  C07D29/24

CPC classification number: C07D227/04 ,  C07D211/22

Abstract: The compounds are of the class of aralkyl penta- and hexamethylenimines which are useful as anti-arrhythmic agents; and to certain intermediates useful in the syntheses of such methylenimines.

Abstract translation: 这些化合物是可用作抗心律不齐剂的芳族五烷基和六亚甲基亚胺类; 以及可用于合成这种亚甲基亚胺的某些中间体。

公开(公告)号：US3511844A

公开(公告)日：1970-05-12

申请号：US3511844D

申请日：1968-03-29

Applicant: MCNEILAB INC

Inventor： PLOSTNIEKS JANIS

IPC: C07D211/22 ,  C07D211/26 ,  C07D211/78 ,  C07D29/22 ,  C07D29/28

CPC classification number: C07D211/78 ,  C07D211/22 ,  C07D211/26

公开(公告)号：US3432523A

公开(公告)日：1969-03-11

申请号：US3432523D

申请日：1967-05-02

Applicant: MCNEILAB INC

Inventor： PLOSTNIEKS JANIS

IPC: C07D209/94 ,  C07D27/56 ,  A61K27/00

CPC classification number: C07D209/94