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1.发明申请Milk fractions and milk preparations for treating and/or preventing cox-2 mediated diseases 有权用于治疗和/或预防cox-2介导的疾病的乳成分和乳制剂公开(公告)号：US20070110818A1
公开(公告)日：2007-05-17
申请号：US10571959
申请日：2004-09-13
申请人： Lionel Bovetto , Joerg Hau , Catherine Mace
发明人： Lionel Bovetto , Joerg Hau , Catherine Mace
CPC分类号： A61K35/20 , A23J1/202 , A23J1/205 , A23L33/19 , A23V2002/00 , A61K38/005 , A23V2250/54252 , A23V2200/308
摘要： The present invention pertains to nutritional and pharmaceutical compositions for treating and preventing cyclooxygenase-2 mediated diseases and to a process for increasing the cyclooxygenase-2 inhibiting activity of a product. In addition thereto, the present invention relates to the use of one ore more milk protein fractions and/or one ore more milk protein preparations for inhibiting the activity of cyclooxygenase-2 (COX-2), in particular for the preparation of a medicament or a functional food for treating and preventing cyclooxygenase-2 mediated diseases.
摘要翻译： 本发明涉及用于治疗和预防环氧合酶-2介导的疾病的营养和药物组合物以及用于增加产品的环氧合酶-2抑制活性的方法。 除此之外，本发明涉及一种或多种乳蛋白质级分和/或一种以上乳蛋白制剂用于抑制环氧合酶-2（COX-2）的活性的用途，特别是用于制备药物或 用于治疗和预防环氧合酶-2介导的疾病的功能性食物。
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2.发明授权Milk fractions and milk preparations for treating and/or preventing COX-2 mediated diseases 有权用于治疗和/或预防COX-2介导的疾病的乳成分和乳制剂公开(公告)号：US08012509B2
公开(公告)日：2011-09-06
申请号：US10571959
申请日：2004-09-13
申请人： Lionel Bovetto , Joerg Hau , Catherine Mace
发明人： Lionel Bovetto , Joerg Hau , Catherine Mace
IPC分类号： A61K35/20
CPC分类号： A61K35/20 , A23J1/202 , A23J1/205 , A23L33/19 , A23V2002/00 , A61K38/005 , A23V2250/54252 , A23V2200/308
摘要： The present invention pertains to nutritional and pharmaceutical compositions for treating and preventing cyclooxygenase-2 mediated diseases and to a process for increasing the cyclooxygenase-2 inhibiting activity of a product. In addition thereto, the present invention relates to the use of one ore more milk protein fractions and/or one ore more milk protein preparations for inhibiting the activity of cyclooxygenase-2 (COX-2), in particular for the preparation of a medicament or a functional food for treating and preventing cyclooxygenase-2 mediated diseases.
摘要翻译： 本发明涉及用于治疗和预防环氧合酶-2介导的疾病的营养和药物组合物以及用于增加产品的环氧合酶-2抑制活性的方法。 除此之外，本发明涉及一种或多种乳蛋白质级分和/或一种以上乳蛋白制剂用于抑制环氧合酶-2（COX-2）的活性的用途，特别是用于制备药物或 用于治疗和预防环氧合酶-2介导的疾病的功能性食物。
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公开(公告)号：US20100111933A1
公开(公告)日：2010-05-06
申请号：US12604741
申请日：2009-10-23
IPC分类号： A61K39/395 , C07K14/435 , C07K14/765 , C07K16/00 , A61K38/38 , A61K38/40 , A61K38/16 , A61P3/10
CPC分类号： A23J3/10 , A23L33/19 , A23V2002/00 , C07K14/4732 , A23V2250/54246 , A23V2200/332 , A23V2200/328
摘要： The present invention relates to a milk fraction obtainable by acidification of micellar casein and separation from precipitated casein named acid soluble protein from micellar casein. It was found that the milk fraction and especially certain sub-fractions thereof are bioactive and promote GLP-1 release in vitro. Based on these results, acid soluble protein from micellar casein may be useful in the treatment and the prevention of diabetes type II, obesity and may further be added to formulas directed at other purposes addressing the gastro-intestinal tract.
摘要翻译： 本发明涉及通过胶束酪蛋白的酸化和从胶束酪蛋白中分离出来的称为酸可溶性蛋白质的沉淀酪蛋白得到的乳成分。 发现乳成分，特别是其某些亚级分是生物活性的并且在体外促进GLP-1释放。 基于这些结果，来自胶束酪蛋白的酸溶性蛋白质可用于治疗和预防II型糖尿病，肥胖症，并且可以进一步加入到针对胃肠道的其它目的的配方中。
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公开(公告)号：US08686116B2
公开(公告)日：2014-04-01
申请号：US12604741
申请日：2009-10-23
CPC分类号： A23J3/10 , A23L33/19 , A23V2002/00 , C07K14/4732 , A23V2250/54246 , A23V2200/332 , A23V2200/328
摘要： The present invention relates to a milk fraction obtainable by acidification of micellar casein and separation from precipitated casein named acid soluble protein from micellar casein. It was found that the milk fraction and especially certain sub-fractions thereof are bioactive and promote GLP-1 release in vitro. Based on these results, acid soluble protein from micellar casein may be useful in the treatment and the prevention of diabetes type II, obesity and may further be added to formulas directed at other purposes addressing the gastro-intestinal tract.
摘要翻译： 本发明涉及通过胶束酪蛋白的酸化和从胶束酪蛋白中分离得到的称为酸可溶性蛋白质的沉淀酪蛋白得到的乳成分。 发现乳成分，特别是其某些亚级分是生物活性的并且在体外促进GLP-1释放。 基于这些结果，来自胶束酪蛋白的酸溶性蛋白质可用于治疗和预防II型糖尿病，肥胖症，并且可以进一步加入到针对胃肠道的其它目的的配方中。
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公开(公告)号：US20060276632A1
公开(公告)日：2006-12-07
申请号：US10570184
申请日：2003-08-30
IPC分类号： C07K14/78
CPC分类号： A23J3/10 , A23L33/19 , A23V2002/00 , C07K14/4732 , A23V2250/54246 , A23V2200/332 , A23V2200/328
摘要： The present invention relates to a milk fraction obtainable by acidification of micellar casein and separation from precipitated casein named acid soluble protein from micellar casein. It was found that the milk fraction and especially certain sub-fractions thereof are bioactive and promote GLP-1 release in vitro. Based on these results, acid soluble protein from micellar casein may be useful in the treatment and the prevention of diabetes type II, obesity and may further be added to formulas directed at other purposes addressing the gastro-intestinal tract.
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公开(公告)号：US07629442B2
公开(公告)日：2009-12-08
申请号：US10570184
申请日：2003-08-30
IPC分类号： A23J1/20
CPC分类号： A23J3/10 , A23L33/19 , A23V2002/00 , C07K14/4732 , A23V2250/54246 , A23V2200/332 , A23V2200/328
摘要： The present invention relates to a milk fraction obtainable by acidification of micellar casein and separation from precipitated casein named acid soluble protein from micellar casein. It was found that the milk fraction and especially certain sub-fractions thereof are bioactive and promote GLP-1 release in vitro. Based on these results, acid soluble protein from micellar casein may be useful in the treatment and the prevention of diabetes type II, obesity and may further be added to formulas directed at other purposes addressing the gastro-intestinal tract.
摘要翻译： 本发明涉及通过胶束酪蛋白的酸化和从胶束酪蛋白中分离出来的称为酸可溶性蛋白质的沉淀酪蛋白得到的乳成分。 发现乳成分，特别是其某些亚级分是生物活性的并且在体外促进GLP-1释放。 基于这些结果，来自胶束酪蛋白的酸溶性蛋白质可用于治疗和预防II型糖尿病，肥胖症，并且可以进一步加入到针对胃肠道的其它目的的配方中。
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公开(公告)号：US20070231453A1
公开(公告)日：2007-10-04
申请号：US11691705
申请日：2007-03-27
申请人： Lionel Bovetto , Christophe Schmitt , Martin Beaulieu , Nicolas Carlier , Gerlinde Unterhaslberger
发明人： Lionel Bovetto , Christophe Schmitt , Martin Beaulieu , Nicolas Carlier , Gerlinde Unterhaslberger
IPC分类号： A23J1/00
CPC分类号： A23G9/40 , A23C21/00 , A23C21/026 , A23C21/04 , A23J1/20 , A23J3/08 , A23V2002/00 , A23V2200/25 , A61K9/0009 , A61K9/7015 , A23V2250/54252 , A23V2200/254 , A23V2200/124 , A23V2200/222 , A23V2200/20
摘要： The present invention relates to a method for producing whey proteins in nanoparticulated form and to the nanoparticulated whey proteins thus obtained. Specifically, the present invention pertains to the use of these nanoparticulated whey proteins as emulsifiers, fat substitute, micellar casein substitute, whitening, foaming, texturizing and/or filling agents.
摘要翻译： 本发明涉及一种制备纳米颗粒形式的乳清蛋白和由此获得的纳米颗粒乳清蛋白的方法。 具体地，本发明涉及这些纳米颗粒乳清蛋白作为乳化剂，脂肪替代物，胶束酪蛋白替代品，增白剂，起泡剂，组织化和/或填充剂的用途。
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公开(公告)号：US06737076B2
公开(公告)日：2004-05-18
申请号：US09907109
申请日：2001-07-16
IPC分类号： A61K4700
CPC分类号： A61K38/018 , A23J3/343 , A23L33/18
摘要： A hypoallergenic composition for the induction of protein tolerance in at risk individuals of protein allergy. The composition contains (i) a “non allergenic” protein extensively hydrolyzed basis and/or of (ii) a free amino acid basis. The composition contains, as an active ingredient, at least one tolerogenic peptide of the allergenic protein.
摘要翻译： 用于诱导蛋白质过敏风险个体的蛋白质耐受性的低变应原组合物。 组合物包含（i）广泛水解的基础和/或（ii）游离氨基酸的“非致敏性”蛋白质。 作为活性成分的组合物含有至少一种致敏性蛋白质的耐受性肽。
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