公开(公告)号：US20180340928A1

公开(公告)日：2018-11-29

申请号：US16002991

申请日：2018-06-07

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Kyle Gee ,  Hee Chol Kang ,  Wenjun Zhou ,  Bradley Dubbels ,  Michael Olszowy ,  Michael O'Grady

IPC: G01N33/50 ,  C09B11/28 ,  C07K16/28 ,  C07D471/04 ,  C07C309/61

CPC classification number: G01N33/5005 ,  C07C309/61 ,  C07C2603/24 ,  C07D471/04 ,  C07K16/2812 ,  C09B11/28 ,  G01N33/5014 ,  G01N33/5044

Abstract: Described herein are fluorescent compounds and methods and comprising these compounds. The compounds disclosed herein are carbopyronine reagents that fluoresce in the red portion of the UV/VIS spectrum and provide bright fluorescence intensity, uniform cell staining, and good retention within live cells as well as low toxicity toward cells.

公开(公告)号：US10018617B2

公开(公告)日：2018-07-10

申请号：US15304800

申请日：2015-05-15

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Kyle Gee ,  Hee Chol Kang ,  Wenjun Zhou ,  Bradley Dubbels ,  Michael Olszowy ,  Michael O'Grady

IPC: G01N33/50 ,  C07D471/04 ,  C07C309/61 ,  C07K16/28 ,  C09B11/28

CPC classification number: G01N33/5005 ,  C07C309/61 ,  C07C2603/24 ,  C07D471/04 ,  C07K16/2812 ,  C09B11/28 ,  G01N33/5014 ,  G01N33/5044

Abstract: Described herein are fluorescent compounds and methods and comprising these compounds. The compounds disclosed herein are carbopyronine reagents that fluoresce in the red portion of the UV/VIS spectrum and provide bright fluorescence intensity, uniform cell staining, and good retention within live cells as well as low toxicity toward cells.

公开(公告)号：US10739330B2

公开(公告)日：2020-08-11

申请号：US16002991

申请日：2018-06-07

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Kyle Gee ,  Hee Chol Kang ,  Wenjun Zhou ,  Bradley Dubbels ,  Michael Olszowy ,  Michael O'Grady

IPC: G01N33/50 ,  C09B11/28 ,  C07K16/28 ,  C07C309/61 ,  C07D471/04

Abstract: Described herein are fluorescent compounds and methods and comprising these compounds. The compounds disclosed herein are carbopyronine reagents that fluoresce in the red portion of the UV/VIS spectrum and provide bright fluorescence intensity, uniform cell staining, and good retention within live cells as well as low toxicity toward cells.