公开(公告)号：US5215897A

公开(公告)日：1993-06-01

申请号：US525302

申请日：1990-05-17

Applicant: Keiichi Sakashita ,  Tetsuji Nakamura ,  Ichiro Watanabe

Inventor： Keiichi Sakashita ,  Tetsuji Nakamura ,  Ichiro Watanabe

IPC: C12N9/80 ,  C12P13/04 ,  C12P41/00

CPC classification number: C12N9/80 ,  C12P13/04 ,  C12P41/006 ,  Y10S435/828 ,  Y10S435/874

Abstract: A process for producing an L-amino acid from the corresponding DL- and/or L-amino acid amide represented by the general formula: ##STR1## wherein R is a substituted or unsubstituted alkyl group having one to 4 carbon atoms, a substituted or unsubstituted phenyl group, or a substituted or unsubstituted aralkyl group, by action of an enzyme having hydrolytic activity to L-amino acid amides which is produced by Enterobacter cloacae or Pseudomonas sp.

Abstract translation: 由下列通式表示的相应的DL-和/或L-氨基酸酰胺生产L-氨基酸的方法：其中R是取代或未取代的具有1至4个碳原子的烷基，取代或 未取代的苯基或取代或未取代的芳烷基，通过对由阴沟肠杆菌或假单胞菌属（Pseudomonas sp。）产生的L-氨基酸酰胺具有水解活性的酶的作用。

公开(公告)号：US4421855A

公开(公告)日：1983-12-20

申请号：US292848

申请日：1981-08-14

Applicant: Ichiro Watanabe ,  Keiichi Sakashita ,  Yasuo Ogawa

Inventor： Ichiro Watanabe ,  Keiichi Sakashita ,  Yasuo Ogawa

IPC: C12N11/04 ,  C12N11/08 ,  C12P13/02 ,  C12R1/15 ,  C12R1/365

CPC classification number: C12N11/04 ,  C12P13/02

Abstract: A process is described for producing acrylamide from acrylonitrile using an immobilized microorganism containing gel, which comprises immobilizing a microorganism having nitrilasic activity with a cationic acrylamide-based polymer gel and bringing acrylonitrile into contact with the immobilized microorganism gel in an aqueous medium containing substantially no salt.

Abstract translation: 描述了一种用于使用固定化的含有微生物的凝胶从丙烯腈制备丙烯酰胺的方法，该方法包括用阳离子丙烯酰胺类聚合物凝胶固定具有亚硝酸活性的微生物，并使丙烯腈与基本上不含盐的水性介质中的固定化微生物凝胶接触 。

公开(公告)号：US5166061A

公开(公告)日：1992-11-24

申请号：US555001

申请日：1990-07-20

Applicant: Tetsuji Nakamura ,  Fujio Yu ,  Ichiro Watanabe

Inventor： Tetsuji Nakamura ,  Fujio Yu ,  Ichiro Watanabe

IPC: C12N1/20 ,  C12P13/00 ,  C12R1/15 ,  C12R1/32

CPC classification number: C12P13/002 ,  Y10S435/822 ,  Y10S435/843

Abstract: A process for the production of a 4-halo-3-hydroxybutyronitrile which comprises reacting a 1,3-dihalo-2-propanol with a dehalogenating enzyme originating from a Corynebacterium or a Microbacterium in the presence of an alkali cyanide to thereby convert the 1,3-dihalo-2-propanol into the 4-halo-3-hydroyxbutyronitrile and collecting the product thus formed is disclosed. According to this process, a 4-halo-3-hydroxybutyronitrile which is highly useful in the syntheses of various medicines and physiologically active substances can be easily and efficiently produced from an inexpensive starting material.

Abstract translation: 一种4-卤代-3-羟基丁腈的制备方法，其包括在碱金属氰化物存在下使1,3-二卤代-2-丙醇与源自棒杆菌或微杆菌的脱卤素酶反应，从而将1 ，3-二卤代-2-丙醇加入到4-卤代-3-羟基丁腈中并收集如此形成的产品。 根据该方法，可以从廉价的原料容易且有效地制备在各种药物和生理活性物质的合成中非常有用的4-卤代-3-羟基丁腈。

公开(公告)号：US5155030A

公开(公告)日：1992-10-13

申请号：US511377

申请日：1990-04-19

Applicant: Tetsuji Nakamura ,  Ichiro Watanabe

Inventor： Tetsuji Nakamura ,  Ichiro Watanabe

IPC: C12P7/18 ,  C12P41/00 ,  C12R1/01 ,  C12R1/15

CPC classification number: C12P7/18 ,  C12P41/00 ,  Y10S435/843

Abstract: A process for preparing an optically active (R)-(-)-3-halo-1,2-propanediol comprising reacting an epihalohydrin with an epihalohydrin hydratase originating from a microorganism. For example, the microorganism belongs to the genus Corynebacterium or the genus Microbacterium. Epihalohydrins which can be used include epichlorohydrin and epibromohydrin. The reaction can be carried out at a temperature of from 5.degree. to 50.degree. C. and a pH of from 4 to 10.

Abstract translation: 一种制备光学活性（R） - （ - ） - 3-卤代-1,2-丙二醇的方法，包括使表卤代醇与源自微生物的表卤代醇水合酶反应。 例如，微生物属于棒杆菌属或微杆菌属。 可以使用的包括表氯醇和表溴醇。 该反应可以在5℃至50℃的温度和4至10℃的pH下进行。

公开(公告)号：US4943528A

公开(公告)日：1990-07-24

申请号：US438124

申请日：1989-11-20

Applicant: Tetsuji Nakamura ,  Ichiro Watanabe

Inventor： Tetsuji Nakamura ,  Ichiro Watanabe

IPC: C12P7/18 ,  C12P41/00

CPC classification number: C12P41/00 ,  C12P7/18

Abstract: A process for the production of an optically active (R)-(-)-3-halo-1,2-propanediol which comprises contacting a 1,3-dihalo-2-propanol with a dehalogenase originating from a microorganism belonging to the genus Corynebacterium or Microbacterium. This process makes it possible to produce the (R)-(-)-3-halo-1,2-propanediol, which is highly useful as a starting material in the synthesis of various drugs and physiologically active substances, theoretically at a yield of 100%.

Abstract translation: 一种制备光学活性（R） - （ - ） - 3-卤代-1,2-丙二醇的方法，该方法包括使1,3-二卤-2-丙醇与源自属于该属的微生物的脱卤素酶接触 棒状杆菌或微杆菌。 该方法使得可以生产在各种药物和生理活性物质的合成中作为原料高度有用的（R） - （ - ） - 3-卤代-1,2-丙二醇，理论上以产率 100％。

公开(公告)号：US07659525B2

公开(公告)日：2010-02-09

申请号：US11723578

申请日：2007-03-21

Applicant: Hideaki Ogawa ,  Hiroshi Okamoto ,  Keisuke Hirayama ,  Yuji Kurokawa ,  Hiroyuki Fujisawa ,  Ichiro Watanabe

Inventor： Hideaki Ogawa ,  Hiroshi Okamoto ,  Keisuke Hirayama ,  Yuji Kurokawa ,  Hiroyuki Fujisawa ,  Ichiro Watanabe

IPC: G03C5/00

CPC classification number: B41J2/45

Abstract: An image recording apparatus (1) causes a recording head (20) to move through a distance corresponding to one half of the recording width of the recording head (20) in a sub-scanning direction each time a recording drum (10) makes one rotation. This, light emitting devices (23, 24) record two line data in advance, and thereafter following light emitting devices (21, 22) record the same line data repeatedly at the same position. This increases the energy of laser light beams given to a recording position on a printing plate (P) to accomplish the recording of an image with reliability. The recording speed is not extremely decreased because not all light emitting devices (21 to 24) are used to make the repeated recordings at the same position on the printing plate (P). Further, the construction of optical systems and driving systems in the image recording apparatus is not complicated.

Abstract translation: 图像记录装置（1）使得记录头（20）在每次记录鼓（10）形成一个时，在副扫描方向上使记录头（20）相对于记录头（20）的记录宽度的一半的距离移动 回转。 这样，发光装置（23,24）预先记录两行数据，之后，发光装置（21,22）在同一位置重复记录同一行数据。 这增加了赋予印版（P）上的记录位置的激光束的能量，从而可靠地完成图像的记录。 由于不是所有的发光装置（21〜24）用于在印版（P）上的同一位置进行重复记录，因此记录速度不会极度降低。 此外，图像记录装置中的光学系统和驱动系统的构造并不复杂。

公开(公告)号：US06845068B2

公开(公告)日：2005-01-18

申请号：US10107691

申请日：2002-03-27

Applicant: Ichiro Watanabe

Inventor： Ichiro Watanabe

IPC: G11B7/09 ,  G11B7/095 ,  G11B11/105 ,  G11B7/00

CPC classification number: G11B7/0956 ,  G11B11/10576

Abstract: In a focus control for following a focus position of light beam to be radiated to an optical disk to an optical disk surface, the technique is for shorten the memory length in the learning controller. The learning controller is provided to a focus feedback control system and updates the memory comprised of N numbers of memory cells with a shorter sample period than a time obtained by dividing the time required for one rotation of the disk by N numbers and outputs the learning results in the memory with the shorter sample period.

Abstract translation: 在将光辐射到光盘的光束的聚焦位置跟随到光盘表面的聚焦控制中，该技术用于缩短学习控制器中的存储器长度。 将学习控制器提供给聚焦反馈控制系统，并且以比通过将盘的一次旋转所需的时间除以N数所获得的时间更短的采样周期来更新包含N个存储单元的存储器，并输出学习结果 在具有较短采样周期的存储器中。

公开(公告)号：US06341107B1

公开(公告)日：2002-01-22

申请号：US09229384

申请日：1999-01-11

Applicant: Ichiro Watanabe

Inventor： Ichiro Watanabe

IPC: G11B700

CPC classification number: G11B7/08517 ,  G11B11/10563

Abstract: A control unit positions a laser beam toward a target track on a medium on the basis of a tracking error signal (TES) Y indicative of a positional deviation amount from a track center as a zero point on the basis of return light from the medium. A position signal correcting unit executes a correcting arithmetic operation using a non-linear function such as a quadratic polynomial, a quadratic monomial equation, or the like to the TES Y and outputs a corrected TES Z obtained by correcting detection sensitivity characteristics to desired characteristics so that a feedback is sufficiently performed when a lead-in control to the track center by the control unit is executed.

Abstract translation: 基于来自介质的返回光，基于表示作为零点的轨道中心的位置偏差量的跟踪误差信号（TES）Y，控制单元将激光束朝向介质上的目标轨道定位。 位置信号校正单元使用诸如二次多项式，二次单项式等非线性函数对TES Y执行校正算术运算，并输出通过将检测灵敏度特性校正为期望特性而获得的经校正的TES Z，从而 当执行由控制单元对轨道中心的引入控制时，充分执行反馈。

公开(公告)号：US5521843A

公开(公告)日：1996-05-28

申请号：US119228

申请日：1993-09-28

Applicant: Masayoshi Hashima ,  Fumi Hasegawa ,  Keiju Okabayashi ,  Ichiro Watanabe ,  Shinji Kanda ,  Naoyuki Sawasaki ,  Yuichi Murase

Inventor： Masayoshi Hashima ,  Fumi Hasegawa ,  Keiju Okabayashi ,  Ichiro Watanabe ,  Shinji Kanda ,  Naoyuki Sawasaki ,  Yuichi Murase

IPC: B25J9/16 ,  G01S3/786 ,  G01S5/16 ,  G05D1/02 ,  G06K9/46 ,  G06T7/20 ,  G01S15/06

CPC classification number: G06K9/4647 ,  B25J9/1697 ,  B64G1/646 ,  G01S3/7864 ,  G01S5/163 ,  G06K9/3216 ,  G06T7/2033 ,  G05B2219/39387 ,  G05B2219/39397 ,  G05B2219/40613 ,  G06K2009/3225

Abstract: A system for and a method of recognizing and tracking a target mark with a video camera is disclosed. The system includes a target mark (10) disposed on an object (1) and composed of a black circle and a white triangle mounted centrally on the black circle and three-dimensionally shifted from the black circle, a video camera (20) for imaging the target mark (10), a robot (30) supporting the video camera (20) and movable in directions with six degrees of freedom, an image processor (40) for processing image data of the target mark which is produced by the video camera (20), a shift calculating unit (50) for detecting a shift of the target mark (10) from projected histogram information of the target mark (10) which is produced by the image processor (40), and a robot controller (60) for controlling movement of the robot depending on the shift to enable the video camera (20) to track the target mark (10). The system is capable of tracking the target mark ( 20) attached to the object (1) on a real-time basis. Mark recognizing apparatus capable of accurately recognizing target marks of other shapes is also disclosed.

Abstract translation: PCT No.PCT / JP93 / 00107 Sec。 371日期：1993年9月28日 102（e）日期1993年9月28日PCT 1993年1月29日PCT公布。 第WO93 / 15376号公报 日期：1993年8月5日。公开了一种使用摄像机识别和跟踪目标标记的系统和方法。 该系统包括设置在物体（1）上并由黑色圆圈和白色三角形组成的目标标记（10），其安装在黑色圆圈的中心并从黑色圆圈三维位移，用于成像的摄像机（20） 所述目标标记（10），支持所述摄像机（20）并且能够以六自由度的方向移动的机器人（30），用于处理由所述摄像机产生的所述目标标记的图像数据的图像处理器 （20），用于根据由图像处理器（40）产生的目标标记（10）的投影直方图信息和机器人控制器（60）检测目标标记（10）的偏移的移位计算单元（50） ），用于根据移动来控制机器人的运动，以使得摄像机（20）能够跟踪目标标记（10）。 该系统能够实时跟踪附接到对象（1）的目标标记（20）。 还公开了能够准确地识别其他形状的目标标记的标记识别装置。

公开(公告)号：US4343900A

公开(公告)日：1982-08-10

申请号：US194653

申请日：1980-10-06

Applicant: Ichiro Watanabe

Inventor： Ichiro Watanabe

IPC: C12P1/00 ,  C12P13/02 ,  C12N11/08 ,  C12R1/15 ,  C12R1/365

CPC classification number: C12P13/02 ,  C12P1/00 ,  Y10S435/843 ,  Y10S435/872

Abstract: This invention provides a process for the production of acrylamide from acrylonitrile in an aqueous medium by use of a microorganism having nitrilasic activity, wherein at least one compound selected from alkali metal carbonates and bicarbonates is added to the aqueous medium, either solely or in combination with an organic carboxylic acid, thus inhibiting the swelling of fixed cells, maintaining the enzymatic activity for a long period of time, and efficiently obtaining an aqueous solution of acrylamide having high quality.

Abstract translation: 本发明提供了一种通过使用具有亚硝酸活性的微生物在水性介质中由丙烯腈制备丙烯酰胺的方法，其中将至少一种选自碱金属碳酸盐和碳酸氢盐的化合物单独或与 有机羧酸，从而抑制固定细胞的溶胀，长时间保持酶活性，有效地获得高质量的丙烯酰胺水溶液。