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公开(公告)号：US09901272B2
公开(公告)日：2018-02-27
申请号：US15185454
申请日：2016-06-17
发明人： Inchan Youn , Kuiwon Choi , Jun-Kyo Francis Suh , Seung-Jong Kim , Hyung Min Kim , Youn Joo Lee , Inwon Jung , Heesu Park , Sunghee Park , Jeong Hwan Kim
IPC分类号： A61B5/0428 , A61B5/0402 , A61B5/00
CPC分类号： A61B5/0402 , A61B5/0006 , A61B5/6824 , A61B5/6828 , A61B5/6829 , A61B5/6831 , A61B5/7225 , A61B5/725 , A61B5/7278 , A61B5/742 , A61B5/7475
摘要： Disclosed is an apparatus for measuring electrocardiogram (ECG) using wireless communication, including a first measuring device and a second measuring device connected to each other using wireless communication, wherein the first measuring device includes a first electrode configured to measure a first signal generated by a heartbeat, and a slave signal generation unit configured to generate a slave signal based on the first signal and a wireless virtual ground signal received from the second measuring device, and the second measuring device includes a second electrode configured to measure a second signal generated by a heartbeat, a ground electrode configured to measure a ground signal, a wireless virtual ground unit configured to generate the wireless virtual ground signal based on the ground signal, and an ECG measuring unit configured to measure ECG based on the slave signal, the second signal, and the wireless virtual ground signal.
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公开(公告)号：US20170080256A1
公开(公告)日：2017-03-23
申请号：US15262370
申请日：2016-09-12
发明人： Hyung Min KIM , Seung-Jong KIM , Inchan Youn , Jong Min LEE
IPC分类号： A61N7/00 , A61B5/00 , A61B5/0476
CPC分类号： A61N7/00 , A61B5/0476 , A61B5/055 , A61B5/14542 , A61B5/4064 , A61B5/4836 , A61N2007/0021 , A61N2007/0026
摘要： A brain to brain interface system has a brain activity detection device configured to detect activity state information of a brain, a brain stimulation device configured to stimulate an area of at least a part of the brain to activate or inactivate brain cells of the corresponding area, and a computer configured to control the brain activity detection device and the brain stimulation device, wherein brain activity state information of a subject's brain (“a target brain”) is obtained through the brain activity detection device, and an area of at least a part of the target brain is stimulated through the brain stimulation device based on the brain activity state information of the target brain to regulate a function of the target brain.
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公开(公告)号：US11759676B2
公开(公告)日：2023-09-19
申请号：US17672797
申请日：2022-02-16
发明人： Song Joo Lee , Choong Hyun Kim , Inchan Youn , Sungmin Han
IPC分类号： A63B23/10 , A63B21/02 , A63B21/00 , A63B23/035 , A63B21/05 , A63B21/04 , A63B21/015
CPC分类号： A63B23/10 , A63B21/00069 , A63B21/015 , A63B21/023 , A63B21/0428 , A63B21/05 , A63B21/4034 , A63B21/4049 , A63B23/03508
摘要： The training apparatus according to an embodiment includes: a support unit; a guide unit fixed on the support unit and including rails which extend in a front-rear direction; a sliding unit which is movable in the front-rear direction along the rails of the guide unit; a pillar-shaped rotation axis fixed on the support unit; a footrest unit which supports a user's foot; a lower support formed below the footrest unit; and a connection rotating unit formed below the footrest unit and connected to the rotation axis of the support unit through insertion to allow the footrest unit to rotate around the rotation axis. A plurality of springs installed inward from two sidewalls of the sliding unit is configured to come into contact with the lower support of the footrest unit and apply pressure from two sides when the footrest unit rotates.
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公开(公告)号：US11231778B2
公开(公告)日：2022-01-25
申请号：US16902040
申请日：2020-06-15
发明人： Hyunseon Seo , Inchan Youn , Hyojin Lee , Kang-Il Song , Donghee Son
IPC分类号： H05K1/18 , G06F3/01 , C08K3/08 , C08G77/388 , H05K1/02 , H05K1/09 , H05K3/14 , H05K3/28 , H05K1/11
摘要： A bidirectional self-healing neural interface includes a first elastic substrate; a neural electrode disposed on the first elastic substrate and comprising a conductive polymer composite; and a second elastic substrate disposed on the neural electrode. The conductive polymer composite includes a matrix formed of a self-healing polymer material; and a plurality of electrical conductor clusters distributed in the matrix. Each of the electrical conductor clusters includes particles of a first electrical conductor; and a plurality of particles of a second electrical conductor formed of the same material as that of the first electrical conductor, distributed around each of the particles of the first electrical conductor, and having sizes that are smaller than those of the particles of the first electrical conductor. The first electrical conductor is a source for generating the second electrical conductor. The neural interface has excellent elasticity, electrical conductivity that is improved by deformation, and is self-healing.
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公开(公告)号：US20200061904A1
公开(公告)日：2020-02-27
申请号：US16548412
申请日：2019-08-22
发明人： Hyung Min Kim , Ki Joo Pahk , Byung Chul Lee , Inchan Youn
IPC分类号： B29C64/106 , B29C64/393 , B33Y10/00 , B33Y30/00 , B33Y50/02
摘要： According to an embodiment of the present disclosure, there is provided a completely new type of 3-dimensional (3D) printing method for producing an object by focusing ultrasound onto material that changes in state by stimulation to solidify it into a desired shape. The method for 3D printing according to an embodiment includes providing material which changes in state by stimulation, setting a target focal point in the material, focusing ultrasound onto the target focal point using at least one ultrasound transducer, and applying stimulation to the material using the focused ultrasound to induce a change in state of the material. According to the embodiments, it is possible to control the precision of the output by controlling the frequency of the ultrasound transducer or the size of the target focal point on system.
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公开(公告)号：US11452887B2
公开(公告)日：2022-09-27
申请号：US15695804
申请日：2017-09-05
发明人： Hyung Min Kim , Inchan Youn , Seung-Jong Kim , Junhyuk Choi , Hongchae Baek , Chan Yul Jung
摘要： A guide framework for positioning an ultrasonic transducer which emits a focused ultrasound to a target point in carrying out surgery to apply ultrasonic stimulation to a subject's brain, includes a body in a shape of a mask that is laid on the subject's face, and a positioning hole formed through an inner surface and an outer surface of the mask body, the positioning hole into which the ultrasonic transducer is inserted, wherein the inner surface of the mask body is formed to conform a facial contour of the subject, and when the guide framework is laid on the subject's face and the ultrasonic transducer is disposed at the positioning hole, the position of the target point is naturally disposed at a preset stimulation site of the brain. An ultrasonic stimulation device includes an ultrasonic transducer and the guide framework for positioning the ultrasonic transducer.
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7.发明授权公开(公告)号：US09259493B2
公开(公告)日：2016-02-16
申请号：US14074865
申请日：2013-11-08
发明人： Kwang Meyung Kim , Ick Chan Kwon , Inchan Youn , Hyun Su Min , Hong Yeol Yoon , Jae Hyung Park
CPC分类号： A61K49/223 , A61K49/0032 , A61K49/0069
摘要： Disclosed is a liver tumor-targeting ultrasound contrast agent. The ultrasound contrast agent includes a gas-generating core and a hyaluronic acid shell. The ultrasound contrast agent can be specifically delivered to liver cells. This specific delivery enables easy differentiation between normal liver cells and liver tumor cells by ultrasound imaging. In addition, the ultrasound contrast agent is highly stable in aqueous condition and causes no cytotoxicity. Also disclosed is a method for preparing the ultrasound contrast agent.
摘要翻译： 公开了一种肝肿瘤靶向超声造影剂。 超声造影剂包括产气芯和透明质酸壳。 可以将超声造影剂特异性地递送至肝细胞。 这种特异性的传递使得通过超声成像容易地在正常肝细胞和肝肿瘤细胞之间分化。 此外，超声造影剂在水性条件下高度稳定，不产生细胞毒性。 还公开了一种制备超声造影剂的方法。
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8.发明授权Tumor-targeting gas-generating nanoparticle, method for preparing the same, and tumor-targeting nanoparticle for drug delivery using the same 有权肿瘤靶向产生气体的纳米颗粒，其制备方法和用于药物递送的肿瘤靶向纳米颗粒公开(公告)号：US09259395B2
公开(公告)日：2016-02-16
申请号：US13906963
申请日：2013-05-31
发明人： Ick Chan Kwon , Kwang Meyung Kim , Kuiwon Choi , Heebeom Koo , Hyun Su Min , Inchan Youn
CPC分类号： A61K9/5146 , A61K9/0004 , A61K9/0009 , A61K9/0019 , A61K9/5153 , A61K41/0028 , A61K47/6925 , A61K49/0032 , A61K49/0054 , A61K49/0093 , A61K49/222 , A61K49/225
摘要： A tumor-targeting gas-generating nanoparticle, a method for preparing same and a tumor-targeting nanoparticle for drug delivery using same relate to a tumor-targeting gas-generating nanoparticle including a polycarbonate core and a amphiphilic coat, a method for preparing same and a tumor-targeting nanoparticle for drug delivery using same. Since a tumor-targeting gas-generating nanoparticle according to the present disclosure is accumulated in the tumor tissue in large quantity and generates strong ultrasound wave signals, it can be usefully used as a contrast agent for ultrasonic imaging.
摘要翻译： 肿瘤靶向产生气体的纳米颗粒，其制备方法和使用其的药物递送的肿瘤靶向纳米颗粒涉及包含聚碳酸酯芯和两亲性涂层的肿瘤靶向产生气体的纳米颗粒，其制备方法和 用于药物递送的肿瘤靶向纳米颗粒。 由于根据本发明的肿瘤靶向产生气体的纳米颗粒大量积聚在肿瘤组织中，并且产生强大的超声波信号，因此可以有效地用作超声成像造影剂。
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公开(公告)号：US10206597B2
公开(公告)日：2019-02-19
申请号：US15077172
申请日：2016-03-22
发明人： Jinseok Kim , Jong Woong Park , Jinwoo Jeong , Inchan Youn , Ockchul Kim , Sang Rok Oh , Keehoon Kim , Jun Uk Chu
摘要： A nerve probe array has a connector made of a flexible material; and a plurality of probes coupled to the connector, each of the plurality of probe having an electrode formed at a body thereof. The plurality of probes are arranged with intervals in a length direction of the connector, and the connector surrounds an outer circumference of a nerve, and the plurality of probes pierce the outer circumference of the nerve and are inserted into the nerve.
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10.发明申请公开(公告)号：US20140140934A1
公开(公告)日：2014-05-22
申请号：US14074865
申请日：2013-11-08
发明人： Kwang Meyung Kim , Ick Chan Kwon , Inchan Youn , Hyun Su Min , Hong Yeol Yoon , Jae Hyung Park
IPC分类号： A61K49/22
CPC分类号： A61K49/223 , A61K49/0032 , A61K49/0069
摘要： Disclosed is a liver tumor-targeting ultrasound contrast agent. The ultrasound contrast agent includes a gas-generating core and a hyaluronic acid shell. The ultrasound contrast agent can be specifically delivered to liver cells. This specific delivery enables easy differentiation between normal liver cells and liver tumor cells by ultrasound imaging. In addition, the ultrasound contrast agent is highly stable in aqueous condition and causes no cytotoxicity. Also disclosed is a method for preparing the ultrasound contrast agent.
摘要翻译： 公开了一种肝肿瘤靶向超声造影剂。 超声造影剂包括产气芯和透明质酸壳。 可以将超声造影剂特异性地递送至肝细胞。 这种特异性的传递使得通过超声成像能够容易地在正常肝细胞和肝肿瘤细胞之间进行分化。 此外，超声造影剂在水性条件下高度稳定，不产生细胞毒性。 还公开了一种制备超声造影剂的方法。
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