公开(公告)号：US10995153B2

公开(公告)日：2021-05-04

申请号：US16074530

申请日：2016-09-20

Applicant: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Hak-Sung Kim ,  Sukyo Jeong ,  Woosung Heu ,  Jong-Won Kim ,  Joong-Jae Lee

IPC: C07K16/46 ,  C07K14/195 ,  C12N15/62 ,  C12N15/63 ,  G01N33/531 ,  G01N33/543 ,  C12N15/70 ,  G01N33/532 ,  C07K14/705 ,  G01N33/544

Abstract: The present invention relates to a novel polypeptide that binds selectively to mouse or rabbit immunoglobulin G. More specifically, the present invention relates to a polypeptide that binds to mouse or rabbit immunoglobulin G, a polynucleotide encoding the polypeptide, an expression vector comprising the polynucleotide, a transformant introduced with the expression vector, a method of producing the polypeptide using the transformant, and a composition for immunoassay comprising the polypeptide. The novel peptide according to the present invention binds specifically to mouse or rabbit immunoglobulin G, can replace conventional expensive secondary immunoglobulin G, and can be used in various biological immunoassays. In addition, a conjugate of the polypeptide of the present invention and immunoglobulin G is useful for fabrication of various immunosensors/immunochips and for drug screening.

公开(公告)号：US20190040157A1

公开(公告)日：2019-02-07

申请号：US16074530

申请日：2016-09-20

Applicant: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Hak-Sung Kim ,  Sukyo Jeong ,  Woosung Heu ,  Jong-Won Kim ,  Joong-Jae Lee

IPC: C07K16/46 ,  C07K14/195 ,  C12N15/62 ,  C12N15/70 ,  G01N33/532 ,  G01N33/544

Abstract: The present invention relates to a novel polypeptide that binds selectively to mouse or rabbit immunoglobulin G. More specifically, the present invention relates to a polypeptide that binds to mouse or rabbit immunoglobulin G, a polynucleotide encoding the polypeptide, an expression vector comprising the polynucleotide, a transformant introduced with the expression vector, a method of producing the polypeptide using the transformant, and a composition for immunoassay comprising the polypeptide. The novel peptide according to the present invention binds specifically to mouse or rabbit immunoglobulin G, can replace conventional expensive secondary immunoglobulin G, and can be used in various biological immunoassays. In addition, a conjugate of the polypeptide of the present invention and immunoglobulin G is useful for fabrication of various immunosensors/immunochips and for drug screening.