公开(公告)号：US20180164320A1

公开(公告)日：2018-06-14

申请号：US15580662

申请日：2015-12-16

Applicant: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Jung Hoe Kim ,  Sung Hyeon Lee ,  Seung Yeol Park ,  Hyun Joo An ,  Jae-Han Kim ,  Myung Jin Oh ,  Jin Man Kim ,  Ju A Lee

IPC: G01N33/574 ,  G01N30/86 ,  G01N30/72 ,  C07H5/04

CPC classification number: G01N33/57419 ,  C07H5/04 ,  G01N30/7233 ,  G01N30/8631 ,  G01N2030/027 ,  G01N2560/00

Abstract: The present invention relates to a method of diagnosing colorectal cancer by detection of glycan changes, and more particularly to a method of diagnosing colorectal cancer using mass spectrometry, in which, when specific glycan structures increase, decrease or significantly change due to a change in N-linked glycosylation of a colorectal cancer patient-derived glycoprotein, as detected by mass spectrometry, the glycan structures are selected as diagnostic markers.