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公开(公告)号：US08509918B2
公开(公告)日：2013-08-13
申请号：US13592052
申请日：2012-08-22
IPC分类号： A61N1/05
CPC分类号： A61N1/0551 , A61N1/0553 , Y10T29/49147 , Y10T29/49204 , Y10T29/49208
摘要： In one embodiment, a method, of fabricating a stimulation lead for stimulating tissue of a patient, comprises: providing a lead body, the lead body comprising a plurality of conductors embedded within insulating material; providing a plurality of terminals; electrically coupling the plurality of terminals with the plurality of conductors; providing a plurality of electrodes, the plurality of electrodes comprising a plurality of substantially continuous longitudinal trenches on a surface of the electrodes, the electrodes comprising areas of reflow material forming microstructures substantially continuously along walls of the longitudinal trenches; and electrically coupling the plurality of electrodes with the plurality of conductors.
摘要翻译： 在一个实施例中，制造用于刺激患者组织的刺激引线的方法包括：提供引线体，所述引线主体包括嵌入在绝缘材料内的多个导体; 提供多个终端; 将所述多个端子与所述多个导体电耦合; 提供多个电极，所述多个电极在电极的表面上包括多个基本上连续的纵向沟槽，所述电极包括基本上沿着纵向沟槽的壁连续地形成微结构的区域的回流材料; 并且将所述多个电极与所述多个导体电耦合。
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公开(公告)号：US20130053935A1
公开(公告)日：2013-02-28
申请号：US13592052
申请日：2012-08-22
CPC分类号： A61N1/0551 , A61N1/0553 , Y10T29/49147 , Y10T29/49204 , Y10T29/49208
摘要： In one embodiment, a method, of fabricating a stimulation lead for stimulating tissue of a patient, comprises: providing a lead body, the lead body comprising a plurality of conductors embedded within insulating material; providing a plurality of terminals; electrically coupling the plurality of terminals with the plurality of conductors; providing a plurality of electrodes, the plurality of electrodes comprising a plurality of substantially continuous longitudinal trenches on a surface of the electrodes, the electrodes comprising areas of reflow material forming microstructures substantially continuously along walls of the longitudinal trenches; and electrically coupling the plurality of electrodes with the plurality of conductors.
摘要翻译： 在一个实施例中，制造用于刺激患者组织的刺激引线的方法包括：提供引线体，所述引线主体包括嵌入在绝缘材料内的多个导体; 提供多个终端; 将所述多个端子与所述多个导体电耦合; 提供多个电极，所述多个电极在电极的表面上包括多个基本上连续的纵向沟槽，所述电极包括基本上沿着纵向沟槽的壁连续地形成微结构的区域的回流材料; 并且将所述多个电极与所述多个导体电耦合。
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公开(公告)号：US08271098B2
公开(公告)日：2012-09-18
申请号：US12604251
申请日：2009-10-22
IPC分类号： A61N1/05
CPC分类号： A61N1/0551 , A61N1/0553 , Y10T29/49147 , Y10T29/49204 , Y10T29/49208
摘要： In one embodiment, a method, of fabricating a stimulation lead for stimulating tissue of a patient, comprises: providing a lead body, the lead body comprising a plurality of conductors embedded within insulating material; providing a plurality of terminals; electrically coupling the plurality of terminals with the plurality of conductors; providing a plurality of electrodes, the plurality of electrodes comprising a plurality of substantially continuous longitudinal trenches on a surface of the electrodes, the electrodes comprising areas of reflow material forming microstructures substantially continuously along walls of the longitudinal trenches; and electrically coupling the plurality of electrodes with the plurality of conductors.
摘要翻译： 在一个实施例中，制造用于刺激患者组织的刺激引线的方法包括：提供引线体，所述引线主体包括嵌入在绝缘材料内的多个导体; 提供多个终端; 将所述多个端子与所述多个导体电耦合; 提供多个电极，所述多个电极在电极的表面上包括多个基本上连续的纵向沟槽，所述电极包括基本上沿着纵向沟槽的壁连续地形成微结构的区域的回流材料; 并且将所述多个电极与所述多个导体电耦合。
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公开(公告)号：US20100100165A1
公开(公告)日：2010-04-22
申请号：US12604251
申请日：2009-10-22
CPC分类号： A61N1/0551 , A61N1/0553 , Y10T29/49147 , Y10T29/49204 , Y10T29/49208
摘要： In one embodiment, a method, of fabricating a stimulation lead for stimulating tissue of a patient, comprises: providing a lead body, the lead body comprising a plurality of conductors embedded within insulating material; providing a plurality of terminals; electrically coupling the plurality of terminals with the plurality of conductors; providing a plurality of electrodes, the plurality of electrodes comprising a plurality of substantially continuous longitudinal trenches on a surface of the electrodes, the electrodes comprising areas of reflow material forming microstructures substantially continuously along walls of the longitudinal trenches; and electrically coupling the plurality of electrodes with the plurality of conductors.
摘要翻译： 在一个实施例中，制造用于刺激患者组织的刺激引线的方法包括：提供引线体，所述引线主体包括嵌入在绝缘材料内的多个导体; 提供多个终端; 将所述多个端子与所述多个导体电耦合; 提供多个电极，所述多个电极在电极的表面上包括多个基本上连续的纵向沟槽，所述电极包括基本上沿着纵向沟槽的壁连续地形成微结构的区域的回流材料; 并且将所述多个电极与所述多个导体电耦合。
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公开(公告)号：US09254349B2
公开(公告)日：2016-02-09
申请号：US13147236
申请日：2010-02-09
CPC分类号： A61L27/303 , A61L27/306 , A61L31/084 , A61L31/088
摘要： The present invention relates to a medical device comprising both pyrolytic carbon and an NO generator, methods of making same, and methods of using same.
摘要翻译： 本发明涉及包含热解碳和NO发生器的医疗装置，其制备方法及其使用方法。
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公开(公告)号：US20100114279A1
公开(公告)日：2010-05-06
申请号：US12447984
申请日：2006-10-31
申请人： Hans Strandberg , Anna Norlin-Weissenrieder , Leda Henriquez , Eva Harström , Mikael Sjögren , Annika Naeslund , Susanne Nilsson , Olof Stegfeldt
发明人： Hans Strandberg , Anna Norlin-Weissenrieder , Leda Henriquez , Eva Harström , Mikael Sjögren , Annika Naeslund , Susanne Nilsson , Olof Stegfeldt
IPC分类号： A61N1/00
CPC分类号： A61N1/05 , A61N1/056 , H01B7/0823
摘要： A medical implantable lead has a proximal end and a distal end, and a flexible flat elongate body. The elongate body includes a layer of strip conductors extending along the length of the flat elongate body, a top insulating layer, and a bottom insulating layer. The layer of strip conductors is sealingly enclosed between the top and bottom insulating layers, and at least a major portion of the flat elongate body is twisted into an elongate helical portion having a central cavity extending longitudinally of the helical portion.
摘要翻译： 医用可植入引线具有近端和远端，以及柔性扁平细长体。 细长主体包括沿扁平细长体的长度延伸的条形导体层，顶部绝缘层和底部绝缘层。 带状导体层被密封地封闭在顶部和底部绝缘层之间，并且扁平细长体的至少大部分被扭转成具有沿螺旋部分纵向延伸的中心空腔的细长螺旋部分。
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公开(公告)号：US20100016935A1
公开(公告)日：2010-01-21
申请号：US12447021
申请日：2006-10-25
申请人： Hans Strandberg , Anna Norlin-Weissenrieder , Leda Henriquez , Eva Harström , Mikael Sjögren , Annika Naeslund
发明人： Hans Strandberg , Anna Norlin-Weissenrieder , Leda Henriquez , Eva Harström , Mikael Sjögren , Annika Naeslund
CPC分类号： A61N1/056 , A61N1/05 , Y10T29/49124
摘要： A implantable lead an elongate body including a flexible insulating tube, and a tubular conductor layer formed of multiple separate strip conductors, which are arranged at the outer surface of the insulating tube and extend along the length thereof.
摘要翻译： 可植入引线，包括柔性绝缘管的细长主体和由多个分离的带状导体形成的管状导体层，其布置在绝缘管的外表面并沿其长度延伸。
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公开(公告)号：US09820727B2
公开(公告)日：2017-11-21
申请号：US13391878
申请日：2010-08-20
CPC分类号： A61B17/0057 , A61B2017/00637 , A61B2017/0065 , A61B2017/00654 , A61B2017/00898 , A61B2017/347
摘要： A tissue puncture closure device includes a carrier tube and a sealing plug. The carrier tube includes a distal end configured for insertion into the tissue puncture. The sealing plug is positioned in the carrier tube and arranged for ejection from the distal end of the carrier tube into the tissue puncture. The sealing plug includes a first collagen portion having a first cross-linked chemical structure, and a second collagen portion positioned proximal of the first collagen portion in the carrier tube. The second collagen portion has a second cross-linked chemical structure that is different from the first cross-linked chemical structure.
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公开(公告)号：US08224457B2
公开(公告)日：2012-07-17
申请号：US12447984
申请日：2006-10-31
申请人： Hans Strandberg , Anna Norlin-Weissenrieder , Leda Henriquez , Eva Harström , Mikael Sjögren , Annika Naeslund , Susanne Nilsson , Olof Stegfeldt
发明人： Hans Strandberg , Anna Norlin-Weissenrieder , Leda Henriquez , Eva Harström , Mikael Sjögren , Annika Naeslund , Susanne Nilsson , Olof Stegfeldt
IPC分类号： A61N1/05
CPC分类号： A61N1/05 , A61N1/056 , H01B7/0823
摘要： A medical implantable lead has a proximal end and a distal end, and a flexible flat elongate body. The elongate body includes a layer of strip conductors extending along the length of the flat elongate body, a top insulating layer, and a bottom insulating layer. The layer of strip conductors is sealingly enclosed between the top and bottom insulating layers, and at least a major portion of the flat elongate body is twisted into an elongate helical portion having a central cavity extending longitudinally of the helical portion.
摘要翻译： 医用可植入引线具有近端和远端，以及柔性扁平细长体。 细长主体包括沿扁平细长体的长度延伸的条形导体层，顶部绝缘层和底部绝缘层。 带状导体层被密封地封闭在顶部和底部绝缘层之间，并且扁平细长体的至少大部分被扭转成具有沿螺旋部分纵向延伸的中心空腔的细长螺旋部分。
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公开(公告)号：US20120310275A1
公开(公告)日：2012-12-06
申请号：US13391878
申请日：2010-08-20
IPC分类号： A61B17/03
CPC分类号： A61B17/0057 , A61B2017/00637 , A61B2017/0065 , A61B2017/00654 , A61B2017/00898 , A61B2017/347
摘要： A tissue puncture closure device includes a carrier tube and a sealing plug. The carrier tube includes a distal end configured for insertion into the tissue puncture. The sealing plug is positioned in the carrier tube and arranged for ejection from the distal end of the carrier tube into the tissue puncture. The sealing plug includes a first collagen portion having a first cross-linked chemical structure, and a second collagen portion positioned proximal of the first collagen portion in the carrier tube. The second collagen portion has a second cross-linked chemical structure that is different from the first cross-linked chemical structure.
摘要翻译： 组织穿刺闭合装置包括载体管和密封塞。 载体管包括构造成用于插入组织穿刺的远端。 密封塞定位在承载管中并布置成从承载管的远端喷射到组织穿刺中。 密封塞包括具有第一交联化学结构的第一胶原部分和位于载体管中的第一胶原部分的近侧的第二胶原部分。 第二胶原部分具有与第一交联化学结构不同的第二交联化学结构。
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