公开(公告)号：US07805175B2

公开(公告)日：2010-09-28

申请号：US11545687

申请日：2006-10-11

申请人： Jium Ming Lin ,  Li-Chern Pan ,  Po-Wei Lin

发明人： Jium Ming Lin ,  Li-Chern Pan ,  Po-Wei Lin

IPC分类号： A61B5/04

CPC分类号： B01J19/0046 ,  B01J2219/00527 ,  B01J2219/00585 ,  B01J2219/00596 ,  B01J2219/00653

摘要： The present invention provides a microarray bioprobe device integrated with a semiconductor amplifier module, which integrates micro array biological probes and thin film transistors on a flexible substrate by Micro-Electro-Mechanical System (MEMS) processes and semiconductor processes. A signal from the microarray bioprobe device is amplified through a near amplifier to increase signal-to-noise ratio and impendence matching. The micro array biological probes of the present invention are produced on the flexible substrate such that the micro array biological probes can be disposed to conform to the profile of a living body's portion and improving contact between the probes and living body's portion.

摘要翻译： 本发明提供了一种与半导体放大器模块集成的微阵列生物探针器件，该半导体放大器模块通过微电子机械系统（MEMS）工艺和半导体工艺在柔性衬底上集成微阵列生物探针和薄膜晶体管。 来自微阵列生物探针器件的信号通过近放大器放大，以增加信噪比和阻抗匹配。 本发明的微阵列生物探针在柔性基板上制造，使得微阵列生物探针可以被设置成符合生物体部分的轮廓并改善探针与活体部分之间的接触。

公开(公告)号：US08606364B2

公开(公告)日：2013-12-10

申请号：US12767592

申请日：2010-04-26

申请人： Jium Ming Lin

发明人： Jium Ming Lin

IPC分类号： A61N1/00

CPC分类号： A61N1/36 ,  A61N1/08 ,  A61N1/37229 ,  A61N1/3727 ,  A61N1/375 ,  H05K1/0393 ,  H05K1/162 ,  H05K1/165 ,  H05K1/167 ,  H05K1/189

摘要： A nerve-stimulating and signal-monitoring device includes a flexible substrate, a modulation/demodulation module, a SOC unit and a plurality of stimulation probes. The modulation/demodulation module demodulates coded nerve-stimulating radio-frequency signals or modulates sending coded epidermal nerve response signals. The SOC unit and the modulation/demodulation module can be integrally packaged and bonded on the flexible substrate. The SOC unit decodes and transforms the coded nerve-stimulating radio-frequency signals to obtain nerve-stimulating electrical probe-driving signals. The stimulation probes protrude from the flexible substrate, are configured to transmit the nerve-stimulating electrical probe-driving signals to epidermal nerves, and are electrically coupled to the SOC unit. The SOC unit can receive, amplify, analyze, classify and encode epidermal nerve response signals sent to the modulation/demodulation module for modulating, and such coded epidermal nerve response signals are subsequently transmitted by an antenna to the monitor station for decoding, monitoring and analysis.

摘要翻译： 神经刺激和信号监测装置包括柔性基板，调制/解调模块，SOC单元和多个刺激探针。 调制/解调模块解调编码的神经刺激射频信号或调制发送编码的表皮神经反应信号。 SOC单元和调制/解调模块可以整体封装在柔性基板上。 SOC单元对编码的神经刺激性射频信号进行解码和变换，以获得神经刺激电探针驱动信号。 刺激探针从柔性基底突出，被配置为将神经刺激电探针驱动信号传输到表皮神经，并且电耦合到SOC单元。 SOC单元可以接收，放大，分析和编码发送到调制/解调模块的表皮神经反应信号进行调制，然后将这种经编码的表皮神经反应信号通过天线发送到监测站进行解码，监测和分析 。

公开(公告)号：US20110036168A1

公开(公告)日：2011-02-17

申请号：US12767597

申请日：2010-04-26

申请人： Jium Ming Lin

发明人： Jium Ming Lin

IPC分类号： G01P15/08

CPC分类号： G01P15/008 ,  G01P15/18 ,  H01L2224/45144 ,  H01L2224/48091 ,  Y10T29/49002 ,  H01L2924/00014 ,  H01L2924/00

摘要： An RFID based thermal bubble type accelerometer includes a flexible substrate, an embedded system on chip (SOC) unit, an RFID antenna formed on the substrate and coupled to a modulation/demodulation module in the SOC unit, a cavity formed on the flexible substrate, and a plurality of sensing assemblies, including a heater and two temperature-sensing elements, disposed along the x-axis direction and suspended over the cavity. The two temperature-sensing elements, serially connected, are separately disposed at two opposite sides and at substantially equal distances from the heater. Two sets of sensing assemblies can be connected in differential Wheatstone bridge. The series-connecting points of the sensing assemblies are coupled to the SOC unit such that an x-axis acceleration can be obtained by a voltage difference between the connecting points. The x-axis acceleration can be sent by the RFID antenna to a reader after it is modulated and encoded by the modulation/demodulation module.

摘要翻译： 一种基于RFID的热泡型加速度计包括柔性基板，嵌入式片上系统（SOC）单元，形成在基板上并耦合到SOC单元中的调制/解调模块的RFID天线，形成在柔性基板上的空腔， 以及包括加热器和两个温度感测元件的多个感测组件，沿x轴方向设置并悬挂在空腔上。 串联连接的两个温度感测元件分别设置在距离加热器两个相对侧和基本相等的距离处。 差分惠斯通电桥可以连接两套感应组件。 感测组件的串联连接点被耦合到SOC单元，使得可以通过连接点之间的电压差来获得x轴加速度。 在由调制/解调模块进行调制和编码之后，x射线加速度可以由RFID天线发送到读取器。

公开(公告)号：US08825150B2

公开(公告)日：2014-09-02

申请号：US13291713

申请日：2011-11-08

申请人： Jium Ming Lin

发明人： Jium Ming Lin

IPC分类号： A61B5/05 ,  A61H39/02

CPC分类号： A61B5/0532 ,  A61B5/0022 ,  A61B5/6806 ,  A61B5/6807 ,  A61B5/7257 ,  A61B2560/0425 ,  A61B2560/0431 ,  A61N1/36017

摘要： A bio-impedance measurement apparatus includes a flexible band member fastened around a body portion, two probe sets attached to the flexible band member, a measurement device, and a wireless device. One probe set includes a probe having a tip portion for piercing the skin of the body portion to be located adjacent to an acupuncture point. Another probe set, used as an electrical ground, includes a probe that contacts the reference skin. The measurement device is disposed on the flexible band member and electrically coupled to the two probe sets to provide an impulse current signal to the acupuncture point. The measurement device amplifies and measures the voltage response across the acupuncture points and the ground. The amplified signal is converted to a digital signal for Fourier transformation. The wireless device, coupled to the measurement device, transmits the acupuncture code and impedance information to a remote monitor station.

摘要翻译： 生物阻抗测量装置包括紧固在主体部分上的柔性带部件，附接到柔性带部件的两个探针组，测量装置和无线装置。 一个探针组包括探针，其具有用于刺穿身体部分的皮肤以邻近穴位的尖端部分。 用作电接地的另一个探针组包括一个与参考皮肤接触的探头。 测量装置设置在柔性带构件上并电耦合到两个探针组，以向针刺点提供脉冲电流信号。 测量装置放大并测量穿过针灸穴和地面的电压响应。 放大的信号被转换成用于傅里叶变换的数字信号。 耦合到测量设备的无线设备将针灸代码和阻抗信息发送到远程监控站。

公开(公告)号：US08307708B2

公开(公告)日：2012-11-13

申请号：US12767597

申请日：2010-04-26

申请人： Jium Ming Lin

发明人： Jium Ming Lin

IPC分类号： G01P15/00 ,  C23F1/00

CPC分类号： G01P15/008 ,  G01P15/18 ,  H01L2224/45144 ,  H01L2224/48091 ,  Y10T29/49002 ,  H01L2924/00014 ,  H01L2924/00

摘要： An RFID based thermal bubble type accelerometer includes a flexible substrate, an embedded system on chip (SOC) unit, an RFID antenna formed on the substrate and coupled to a modulation/demodulation module in the SOC unit, a cavity formed on the flexible substrate, and a plurality of sensing assemblies, including a heater and two temperature-sensing elements, disposed along the x-axis direction and suspended over the cavity. The two temperature-sensing elements, serially connected, are separately disposed at two opposite sides and at substantially equal distances from the heater. Two sets of sensing assemblies can be connected in differential Wheatstone bridge. The series-connecting points of the sensing assemblies are coupled to the SOC unit such that an x-axis acceleration can be obtained by a voltage difference between the connecting points. The x-axis acceleration can be sent by the RFID antenna to a reader after it is modulated and encoded by the modulation/demodulation module.

摘要翻译： 一种基于RFID的热泡型加速度计包括柔性基板，嵌入式片上系统（SOC）单元，形成在基板上并耦合到SOC单元中的调制/解调模块的RFID天线，形成在柔性基板上的空腔， 以及包括加热器和两个温度感测元件的多个感测组件，沿x轴方向设置并悬挂在空腔上。 串联连接的两个温度感测元件分别设置在距离加热器两个相对侧和基本相等的距离处。 差分惠斯通电桥可以连接两套感应组件。 感测组件的串联连接点被耦合到SOC单元，使得可以通过连接点之间的电压差来获得x轴加速度。 在由调制/解调模块进行调制和编码之后，x射线加速度可以由RFID天线发送到读取器。

公开(公告)号：US20120123291A1

公开(公告)日：2012-05-17

申请号：US13291713

申请日：2011-11-08

申请人： Jium Ming Lin

发明人： Jium Ming Lin

IPC分类号： A61B5/053

CPC分类号： A61B5/0532 ,  A61B5/0022 ,  A61B5/6806 ,  A61B5/6807 ,  A61B5/7257 ,  A61B2560/0425 ,  A61B2560/0431 ,  A61N1/36017

摘要： A bio-impedance measurement apparatus includes a flexible band member fastened around a body portion, two probe sets attached to the flexible band member, a measurement device, and a wireless device. One probe set includes a probe having a tip portion for piercing the skin of the body portion to be located adjacent to an acupuncture point. Another probe set, used as an electrical ground, includes a probe that contacts the reference skin. The measurement device is disposed on the flexible band member and electrically coupled to the two probe sets to provide an impulse current signal to the acupuncture point. The measurement device amplifies and measures the voltage response across the acupuncture points and the ground. The amplified signal is converted to a digital signal for Fourier transformation. The wireless device, coupled to the measurement device, transmits the acupuncture code and impedance information to a remote monitor station.

摘要翻译： 生物阻抗测量装置包括紧固在主体部分上的柔性带部件，附接到柔性带部件的两个探针组，测量装置和无线装置。 一个探针组包括探针，其具有用于刺穿身体部分的皮肤以邻近穴位的尖端部分。 用作电接地的另一个探针组包括一个与参考皮肤接触的探头。 测量装置设置在柔性带构件上并电耦合到两个探针组，以向针刺点提供脉冲电流信号。 测量装置放大并测量穿过针灸穴和地面的电压响应。 放大的信号被转换成用于傅里叶变换的数字信号。 耦合到测量设备的无线设备将针灸代码和阻抗信息发送到远程监控站。

公开(公告)号：US20110009926A1

公开(公告)日：2011-01-13

申请号：US12767592

申请日：2010-04-26

申请人： Jium Ming Lin

发明人： Jium Ming Lin

IPC分类号： A61N1/08 ,  H01S4/00

CPC分类号： A61N1/36 ,  A61N1/08 ,  A61N1/37229 ,  A61N1/3727 ,  A61N1/375 ,  H05K1/0393 ,  H05K1/162 ,  H05K1/165 ,  H05K1/167 ,  H05K1/189

摘要： A nerve-stimulating and signal-monitoring device includes a flexible substrate, a modulation/demodulation module, a SOC unit and a plurality of stimulation probes. The modulation/demodulation module demodulates coded nerve-stimulating radio-frequency signals or modulates sending coded epidermal nerve response signals. The SOC unit and the modulation/demodulation module can be integrally packaged and bonded on the flexible substrate. The SOC unit decodes and transforms the coded nerve-stimulating radio-frequency signals to obtain nerve-stimulating electrical probe-driving signals. The stimulation probes protrude from the flexible substrate, are configured to transmit the nerve-stimulating electrical probe-driving signals to epidermal nerves, and are electrically coupled to the SOC unit. The SOC unit can receive, amplify, analyze, classify and encode epidermal nerve response signals sent to the modulation/demodulation module for modulating, and such coded epidermal nerve response signals are subsequently transmitted by an antenna to the monitor station for decoding, monitoring and analysis.

摘要翻译： 神经刺激和信号监测装置包括柔性基板，调制/解调模块，SOC单元和多个刺激探针。 调制/解调模块解调编码的神经刺激射频信号或调制发送编码的表皮神经反应信号。 SOC单元和调制/解调模块可以整体封装在柔性基板上。 SOC单元对编码的神经刺激性射频信号进行解码和变换，以获得神经刺激电探针驱动信号。 刺激探针从柔性基底突出，被配置为将神经刺激电探针驱动信号传输到表皮神经，并且电耦合到SOC单元。 SOC单元可以接收，放大，分析和编码发送到调制/解调模块的表皮神经反应信号进行调制，然后将这种经编码的表皮神经反应信号通过天线发送到监测站进行解码，监测和分析 。

公开(公告)号：US08327707B2

公开(公告)日：2012-12-11

申请号：US12906866

申请日：2010-10-18

申请人： Jium Ming Lin

发明人： Jium Ming Lin

IPC分类号： G01P15/00 ,  C23F1/00

CPC分类号： G01P15/008 ,  G01P15/0802 ,  G01P15/0888 ,  H01L2224/32145 ,  H01L2224/73265

摘要： An RFID, Bluetooth as well as zigbee based thermal bubble type angular accelerometer includes a flexible substrate, a base layer, at least one cavity, and at least one sensing assembly. The base layer is formed on the flexible substrate. The at least one cavity is formed on the base layer. The at least one sensing assembly is suspended over the at least one cavity. The sensing assembly comprises a heater and two temperature sensing elements, wherein the two temperature sensing elements are substantially symmetrically disposed on opposite sides of the heater, and the heaters and the two temperature sensing elements extend in a radial direction.

摘要翻译： RFID，蓝牙以及基于ZigBee的热气泡型角加速度计包括柔性基底，基底层，至少一个空腔和至少一个感测组件。 基层形成在柔性基板上。 至少一个空腔形成在基层上。 所述至少一个感测组件悬挂在所述至少一个腔体上。 感测组件包括加热器和两个温度感测元件，其中两个温度感测元件基本对称地设置在加热器的相对侧上，并且加热器和两个温度感测元件沿径向方向延伸。

公开(公告)号：US20110100123A1

公开(公告)日：2011-05-05

申请号：US12906866

申请日：2010-10-18

申请人： Jium Ming Lin

发明人： Jium Ming Lin

IPC分类号： G01P15/00 ,  G01P15/02

CPC分类号： G01P15/008 ,  G01P15/0802 ,  G01P15/0888 ,  H01L2224/32145 ,  H01L2224/73265

摘要： An RFID, Bluetooth as well as zigbee based thermal bubble type angular accelerometer includes a flexible substrate, a base layer, at least one cavity, and at least one sensing assembly. The base layer is formed on the flexible substrate. The at least one cavity is formed on the base layer. The at least one sensing assembly is suspended over the at least one cavity. The sensing assembly comprises a heater and two temperature sensing elements, wherein the two temperature sensing elements are substantially symmetrically disposed on opposite sides of the heater, and the heaters and the two temperature sensing elements extend in a radial direction.

摘要翻译： RFID，蓝牙以及基于ZigBee的热气泡型角加速度计包括柔性基底，基底层，至少一个空腔和至少一个感测组件。 基层形成在柔性基板上。 至少一个空腔形成在基层上。 所述至少一个感测组件悬挂在所述至少一个腔体上。 感测组件包括加热器和两个温度感测元件，其中两个温度感测元件基本对称地设置在加热器的相对侧上，并且加热器和两个温度感测元件沿径向方向延伸。