公开(公告)号：US20130033887A1

公开(公告)日：2013-02-07

申请号：US13642436

申请日：2011-04-20

申请人： Jin U. Kang ,  Seth D. Billings ,  Peter L. Gehlbach ,  James T. Handa ,  Yong Huang ,  Russell H. Taylor ,  Yi Yang

发明人： Jin U. Kang ,  Seth D. Billings ,  Peter L. Gehlbach ,  James T. Handa ,  Yong Huang ,  Russell H. Taylor ,  Yi Yang

IPC分类号： F21V8/00 ,  G02B6/04 ,  G02B6/30

CPC分类号： G02B6/0006 ,  G02B6/0031 ,  G02B6/4214 ,  G02B6/4298

摘要： An illumination system includes a light source, an optical waveguide that has a proximal end and a distal end such that the proximal end is arranged to receive light from the light source and the distal end is suitable to illuminate an object of interest; and an optical coupler constructed and arranged to couple light from the light source into the optical waveguide. The optical coupler includes a reflective surface that reflects at least some light diverging from the light source to be coupled into the optical waveguide.

摘要翻译： 照明系统包括光源，光波导，其具有近端和远端，使得近端被布置成接收来自光源的光，并且远端适于照射感兴趣的物体; 以及构造和布置成将来自光源的光耦合到光波导中的光耦合器。 光耦合器包括反射表面，该反射表面反射从要耦合到光波导中的光源发散的至少一些光。

公开(公告)号：US09115974B2

公开(公告)日：2015-08-25

申请号：US13618810

申请日：2012-09-14

申请人： Jin U. Kang ,  Yong Huang

发明人： Jin U. Kang ,  Yong Huang

IPC分类号： G01B11/02 ,  G01B9/02 ,  A61B5/00

CPC分类号： G01B9/02076 ,  A61B5/0066 ,  A61B5/6886 ,  A61B5/721 ,  A61B34/75 ,  G01B9/0205 ,  G01B9/02054 ,  G01B9/02068 ,  G01B9/02091

摘要： A motion-compensated optical coherence tomography system includes an optical coherence tomography sensor that includes a common-path optical fiber having an end for emitting light, reflecting reference light and receiving returned light for detection; a motion-compensation system attached to the common-path optical fiber and operable to move at least a portion of the optical fiber so as to compensate for motion between the end of the common-path optical fiber and an object being imaged; and a feedback control system configured to communicate with the optical coherence tomography sensor and the motion-compensation system. The feedback control system is configured to receive information concerning a measured distance of the end of the common-path optical fiber from the object and provide instructions to the motion-compensation system to decrease an amount of deviation of the measured distance from a desired distance.

摘要翻译： 运动补偿光学相干断层摄影系统包括光学相干断层摄影传感器，其包括具有用于发射光的一端的共轨光纤，反射参考光并接收用于检测的返回光; 运动补偿系统，其附接到所述公共路径光纤并且可操作以移动所述光纤的至少一部分，以便补偿所述公共路径光纤的端部与被成像的物体之间的运动; 以及配置成与光学相干断层摄影传感器和运动补偿系统通信的反馈控制系统。 反馈控制系统被配置为从物体接收关于公共路径光纤的端部的测量距离的信息，并且向运动补偿系统提供指令以减少测量距离与期望距离的偏差量。

公开(公告)号：US20140078512A1

公开(公告)日：2014-03-20

申请号：US13618810

申请日：2012-09-14

申请人： Jin U. Kang ,  Yong Huang

发明人： Jin U. Kang ,  Yong Huang

IPC分类号： G01B9/02

CPC分类号： G01B9/02076 ,  A61B5/0066 ,  A61B5/6886 ,  A61B5/721 ,  A61B34/75 ,  G01B9/0205 ,  G01B9/02054 ,  G01B9/02068 ,  G01B9/02091

摘要： A motion-compensated optical coherence tomography system includes an optical coherence tomography sensor that includes a common-path optical fiber having an end for emitting light, reflecting reference light and receiving returned light for detection; a motion-compensation system attached to the common-path optical fiber and operable to move at least a portion of the optical fiber so as to compensate for motion between the end of the common-path optical fiber and an object being imaged; and a feedback control system configured to communicate with the optical coherence tomography sensor and the motion-compensation system. The feedback control system is configured to receive information concerning a measured distance of the end of the common-path optical fiber from the object and provide instructions to the motion-compensation system to decrease an amount of deviation of the measured distance from a desired distance.

摘要翻译： 运动补偿光学相干断层摄影系统包括光学相干断层摄影传感器，其包括具有用于发射光的一端的共轨光纤，反射参考光并接收用于检测的返回光; 运动补偿系统，其附接到所述公共路径光纤并且可操作以移动所述光纤的至少一部分，以便补偿所述公共路径光纤的端部与被成像的物体之间的运动; 以及配置成与光学相干断层摄影传感器和运动补偿系统通信的反馈控制系统。 反馈控制系统被配置为从物体接收关于公共路径光纤的端部的测量距离的信息，并且向运动补偿系统提供指令以减少测量距离与期望距离的偏差量。

公开(公告)号：US20130044330A1

公开(公告)日：2013-02-21

申请号：US13586586

申请日：2012-08-15

申请人： Jin U. Kang ,  Yong Huang

发明人： Jin U. Kang ,  Yong Huang

IPC分类号： G01B9/02

CPC分类号： G01B9/02089 ,  A61B5/0066 ,  G01B9/02044 ,  G01B9/02083 ,  G01B9/02091 ,  G06T5/002

摘要： An optical coherence tomography system having real-time artifact and saturation correction includes an optical coherence tomography unit, and a signal processing and display system adapted to communicate with the optical coherence tomography unit to receive imaging signals therefrom. The optical coherence tomography system is a Fourier Domain optical coherence tomography system. The signal processing and display system includes a parallel processor configured to correct the imaging signals, in real time, to at least partially remove image artifacts and saturation based on a subset of image data within an image frame.

摘要翻译： 具有实时伪影和饱和度校正的光学相干断层摄影系统包括光学相干断层摄影单元，以及适于与光学相干断层摄影单元通信以从其接收成像信号的信号处理和显示系统。 光学相干断层扫描系统是傅立叶域光学相干断层扫描系统。 信号处理和显示系统包括并行处理器，其被配置为实时地校正成像信号，以至少部分地基于图像帧内的图像数据的子集去除图像伪影和饱和度。

公开(公告)号：US09116262B2

公开(公告)日：2015-08-25

申请号：US13642436

申请日：2011-04-20

申请人： Jin U. Kang ,  Seth D. Billings ,  Peter L. Gehlbach ,  James T. Handa ,  Yong Huang ,  Russell H. Taylor ,  Yi Yang

发明人： Jin U. Kang ,  Seth D. Billings ,  Peter L. Gehlbach ,  James T. Handa ,  Yong Huang ,  Russell H. Taylor ,  Yi Yang

IPC分类号： G02B6/42 ,  F21V8/00

CPC分类号： G02B6/0006 ,  G02B6/0031 ,  G02B6/4214 ,  G02B6/4298

摘要： An illumination system includes a light source, an optical waveguide that has a proximal end and a distal end such that the proximal end is arranged to receive light from the light source and the distal end is suitable to illuminate an object of interest; and an optical coupler constructed and arranged to couple light from the light source into the optical waveguide. The optical coupler includes a reflective surface that reflects at least some light diverging from the light source to be coupled into the optical waveguide.

摘要翻译： 照明系统包括光源，光波导，其具有近端和远端，使得近端被布置成接收来自光源的光，并且远端适于照射感兴趣的物体; 以及构造和布置成将来自光源的光耦合到光波导中的光耦合器。 光耦合器包括反射表面，该反射表面反射从要耦合到光波导中的光源发散的至少一些光。

公开(公告)号：US20140063225A1

公开(公告)日：2014-03-06

申请号：US14114885

申请日：2012-05-04

申请人： Kang ZHANG ,  Jin U. KANG ,  Yong HUANG ,  The Johns Hopkins University

发明人： Jin U. Kang ,  Yong Huang ,  Kang Zhang

IPC分类号： G01B9/04

CPC分类号： G01B9/04 ,  A61B5/0066 ,  A61B5/0068 ,  A61B5/721 ,  G02B21/0032

摘要： A motion-compensated confocal microscope includes a laser scanning system, a fiber-optic component having a proximal end and a distal end such that the fiber-optic component is optically coupled to the laser scanning system to receive illumination light at the proximal end and to emit at least a portion of the illumination light at the distal end, and a detection system configured to receive and detect light returned from a specimen being observed and to output an image signal. The light returned from the specimen is received by the distal end of the fiber-optic component and transmitted back and out the proximal end of the fiber-optic component. The motion-compensated confocal microscope also includes a motion compensation system connected to at least one of the distal end of the fiber-optic component or to the specimen to move at least one of the distal end of the fiber-optic component or the specimen to compensate for relative motion between the distal end of the fiber-optic component and a portion of the specimen being observed.

摘要翻译： 运动补偿共焦显微镜包括激光扫描系统，具有近端和远端的光纤部件，使得光纤部件光学耦合到激光扫描系统以在近端接收照明光，并且 发射远端的照明光的至少一部分，以及被配置为接收和检测从观察到的样本返回的光并且输出图像信号的检测系统。 从样品返回的光被光纤部件的远端接收并被传出并离开光纤部件的近端。 运动补偿共聚焦显微镜还包括连接到光纤部件的远端中至少一个或运动补偿系统的运动补偿系统，以将至少一个光纤部件或样本的远端移动到 补偿光纤部件的远端和正在观察的部分试样之间的相对运动。

公开(公告)号：US20120283804A1

公开(公告)日：2012-11-08

申请号：US13464784

申请日：2012-05-04

申请人： Jin U. Kang ,  Yong Huang ,  Kang Zhang

发明人： Jin U. Kang ,  Yong Huang ,  Kang Zhang

IPC分类号： A61N5/067 ,  A61N5/01

CPC分类号： A61F9/00802 ,  A61F9/00821 ,  A61F2009/00851 ,  A61F2009/00863 ,  A61F2009/00874 ,  A61N2005/0644 ,  A61N2005/0659

摘要： A mid-infrared laser therapy tool includes a handle, a mid-infrared laser contained within the handle, and a light pipe optically coupled to the mid-infrared laser. The mid-infrared laser emits at a wavelength within a wavelength band from about 6.0 μm to about 6.5 μm. A mid-infrared laser therapy system includes a mid-infrared laser therapy tool, an optical coherence tomography system adapted to communicate with the mid-infrared laser therapy tool, and a motorized-platform control system adapted to communicate with the mid-infrared laser therapy tool and the optical coherence tomography system. The mid-infrared laser therapy tool comprises a mid-infrared laser emits at a wavelength within a wavelength band from about 6.0 μm to about 6.5 μm.

摘要翻译： 中红外激光治疗工具包括把手，包含在手柄内的中红外激光器和与中红外激光器光耦合的光管。 中红外激光器在从约6.0μm到约6.5μm的波长带内发射波长。 中红外激光治疗系统包括中红外激光治疗工具，适于与中红外激光治疗工具通信的光学相干断层摄影系统，以及适于与中红外激光治疗通信的电动平台控制系统 工具和光学相干断层扫描系统。 中红外激光治疗工具包括在约6.0μm至约6.5μm的波长带内发射的中红外激光。

公开(公告)号：US10045882B2

公开(公告)日：2018-08-14

申请号：US12917168

申请日：2010-11-01

申请人： Marcin A. Balicki ,  Russell H. Taylor ,  Jin U. Kang ,  Peter L. Gehlbach ,  James T. Handa ,  Jaeho Han

发明人： Marcin A. Balicki ,  Russell H. Taylor ,  Jin U. Kang ,  Peter L. Gehlbach ,  James T. Handa ,  Jaeho Han

IPC分类号： A61F9/00 ,  A61F9/007 ,  A61B3/10 ,  A61B3/12 ,  A61B34/00 ,  A61B90/00 ,  A61B34/30

摘要： A surgical instrument has a surgical tool that has a proximal end and a distal end, and an optical sensor that has at least a portion attached to the surgical tool. The surgical tool has a portion that is suitable to provide a reference portion of the surgical tool, and the optical sensor has an end fixed relative to the reference portion of the surgical tool such that the reference portion of the surgical tool can be detected along with tissue that is proximate or in contact with the distal end of the surgical tool while in use.

公开(公告)号：US20120281236A1

公开(公告)日：2012-11-08

申请号：US13464758

申请日：2012-05-04

申请人： Jin U. Kang ,  Kang Zhang

发明人： Jin U. Kang ,  Kang Zhang

IPC分类号： G01B9/02

CPC分类号： G01B9/02089 ,  A61B90/37 ,  A61B2090/3735 ,  G01B9/02044 ,  G01B9/02083 ,  G01B9/02091 ,  G06F21/316 ,  G06F21/46 ,  G06F2221/2133

摘要： A four-dimensional optical coherence tomography imagining and guidance system includes an optical coherence tomography system, a data processing system adapted to communicate with the optical coherence tomography system, and a display system adapted to communicate with the data processing system. The optical coherence tomography system is configured to provide data corresponding to a plurality of volume frames per second. The data processing system is configured to receive and process the data and provide three-dimensional image data to the display system such that the display system displays a rendered real-time three-dimensional image.

摘要翻译： 四维光学相干断层摄影想象和引导系统包括光学相干断层摄影系统，适于与光学相干断层摄影系统通信的数据处理系统，以及适于与数据处理系统进行通信的显示系统。 光学相干断层摄影系统被配置为提供对应于每秒多个体积帧的数据。 数据处理系统被配置为接收和处理数据并向显示系统提供三维图像数据，使得显示系统显示渲染的实时三维图像。

公开(公告)号：US09345397B2

公开(公告)日：2016-05-24

申请号：US13238538

申请日：2011-09-21

申请人： Russell H. Taylor ,  Jin U. Kang ,  John Niparko

发明人： Russell H. Taylor ,  Jin U. Kang ,  John Niparko

IPC分类号： A61B6/00 ,  A61B1/227 ,  A61B1/00 ,  A61B5/00 ,  A61F11/00 ,  A61N1/36

CPC分类号： A61B1/227 ,  A61B1/00172 ,  A61B5/0066 ,  A61F11/004 ,  A61N1/36036

摘要： A sensing system for implant surgery includes an insertion device for moving an implant into a narrow cavity in a patient's body. A sensor measures the distance from an end of the insertion device to anatomic surfaces at a distance from the end of the insertion device. An optical coherence tomography (OCT) system integrates the sensor and produces OCT images, which can be quantified to distance measurements. The system is particularly useful for cochlear implant surgery.

摘要翻译： 用于植入手术的感测系统包括用于将植入物移动到患者体内的狭窄腔中的插入装置。 传感器测量从插入装置的端部到与插入装置的端部相距一定距离的解剖表面的距离。 光学相干断层扫描（OCT）系统集成了传感器并产生OCT图像，可以将其量化为距离测量。 该系统对于人工耳蜗手术特别有用。