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公开(公告)号：US20130331453A1
公开(公告)日：2013-12-12
申请号：US13966493
申请日：2013-08-14
发明人： Gee-Hong Kuo , Rui Zhang , Aihua Wang , Alan R. DeAngelis
IPC分类号： C07C323/20
CPC分类号： A61K31/277 , A61K31/192 , C07C59/68 , C07C59/70 , C07C317/22 , C07C323/20 , C07C323/60 , C07C323/62 , C07D333/16 , C07D333/28
摘要： The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR delta modulators to treat or inhibit the progression of, for example, dyslipidemia.
摘要翻译： 本发明具有4 - （（苯氧基烷基）硫基） - 苯氧基乙酸及其类似物，含有它们的组合物，以及使用它们作为PPARδ调节剂治疗或抑制例如血脂异常进展的方法。
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公开(公告)号：US20190192475A1
公开(公告)日：2019-06-27
申请号：US16292406
申请日：2019-03-05
发明人： Gee-Hong Kuo , Rui Zhang , Aihua Wang , Alan R. DeAngelis
IPC分类号： A61K31/277 , C07C323/20 , C07D333/28 , C07D333/16 , C07C323/62 , A61K31/192 , C07C317/22 , C07C59/70 , C07C59/68 , C07C323/60
CPC分类号： A61K31/277 , A61K31/192 , C07C59/68 , C07C59/70 , C07C317/22 , C07C323/20 , C07C323/60 , C07C323/62 , C07D333/16 , C07D333/28
摘要： The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR delta modulators to treat or inhibit the progression of, for example, dyslipidemia.
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公开(公告)号：US09724322B2
公开(公告)日：2017-08-08
申请号：US15074125
申请日：2016-03-18
发明人： Gee-Hong Kuo , Rui Zhang , Aihua Wang , Alan R. DeAngelis
IPC分类号： A61K31/277 , A61K31/192 , C07C323/20 , C07C59/68 , C07C59/70 , C07C317/22 , C07C323/60 , C07C323/62 , C07D333/16 , C07D333/28
CPC分类号： A61K31/277 , A61K31/192 , C07C59/68 , C07C59/70 , C07C317/22 , C07C323/20 , C07C323/60 , C07C323/62 , C07D333/16 , C07D333/28
摘要： The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR delta modulators to treat or inhibit the progression of, for example, dyslipidemia.
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公开(公告)号：US20230210808A1
公开(公告)日：2023-07-06
申请号：US18120484
申请日：2023-03-13
发明人： Gee-Hong Kuo , Rui Zhang , Aihua Wang , Alan R. DeAngelis
IPC分类号： A61K31/277 , A61K31/192 , C07C59/68 , C07C59/70 , C07C317/22 , C07C323/60 , C07C323/62 , C07D333/16 , C07D333/28 , C07C323/20
CPC分类号： A61K31/277 , A61K31/192 , C07C59/68 , C07C59/70 , C07C317/22 , C07C323/60 , C07C323/62 , C07D333/16 , C07D333/28 , C07C323/20
摘要： The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR delta modulators to treat or inhibit the progression of, for example, dyslipidemia.
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公开(公告)号：US20170304254A1
公开(公告)日：2017-10-26
申请号：US15644993
申请日：2017-07-10
发明人： Gee-Hong Kuo , Rui Zhang , Aihua Wang , Alan R. DeAngelis
IPC分类号： A61K31/277 , C07D333/16 , C07C323/62 , C07C323/20 , A61K31/192 , C07C317/22 , C07C59/70 , C07C59/68 , C07D333/28 , C07C323/60
CPC分类号： A61K31/277 , A61K31/192 , C07C59/68 , C07C59/70 , C07C317/22 , C07C323/20 , C07C323/60 , C07C323/62 , C07D333/16 , C07D333/28
摘要： The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR delta modulators to treat or inhibit the progression of, for example, dyslipidemia.
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公开(公告)号：US20160199342A1
公开(公告)日：2016-07-14
申请号：US15074125
申请日：2016-03-18
发明人： Gee-Hong Kuo , Rui Zhang , Aihua Wang , Alan R. DeAngelis
IPC分类号： A61K31/277 , A61K31/192
CPC分类号： A61K31/277 , A61K31/192 , C07C59/68 , C07C59/70 , C07C317/22 , C07C323/20 , C07C323/60 , C07C323/62 , C07D333/16 , C07D333/28
摘要： The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR delta modulators to treat or inhibit the progression of, for example, dyslipidemia.
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