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    Method and system for placement of electrical lead inside heart
    1.
    发明授权
    Method and system for placement of electrical lead inside heart 有权
    电线内置心脏的方法和系统

    公开(公告)号：US08409219B2

    公开(公告)日：2013-04-02

    申请号：US12570390

    申请日：2009-09-30

    申请人： James F. Kelley ,  Zhongping C. Yang ,  Mark T. Stewart

    发明人： James F. Kelley ,  Zhongping C. Yang ,  Mark T. Stewart

    IPC分类号： A61B19/00

    CPC分类号： A61N1/059 ,  A61B17/12 ,  A61B17/12009 ,  A61B17/128 ,  A61B17/3468 ,  A61B2017/00247 ,  A61B2017/12018 ,  A61B2018/00392

    摘要： A method of placing an electrical lead of an implantable cardiac device inside a heart of a patient. The method includes securing a tool to an atrial appendage of the heart to hold onto the atrial appendage, piercing the atrial appendage, and creating an aperture in the atrial appendage while holding the atrial appendage with the tool. The method also includes moving a distal end of the electrical lead into the heart through the aperture in the atrial appendage and into a ventricle of the heart. Furthermore, the method includes coupling the distal end of the electrical lead to cardiac tissue in the ventricle and delivering an electrical signal to the cardiac tissue in the ventricle of the heart to maintain a predetermined heartbeat of the heart.

    摘要翻译： 将可植入心脏装置的电引线放置在患者心脏内的方法。 该方法包括将工具固定到心脏的心房附着物，以固定在心房附近，刺穿心房附件，以及在用该工具持有心房附件的同时创建心房附近的孔。 该方法还包括通过心耳中的孔将电引线的远端移动到心脏中并进入心脏的心室。 此外，该方法包括将电导线的远端耦合到心室中的心脏组织，并将电信号传送到心脏心室的心脏组织以维持心脏的预定心跳。

    METHOD AND SYSTEM FOR PLACEMENT OF ELECTRICAL LEAD INSIDE HEART
    2.
    发明申请
    METHOD AND SYSTEM FOR PLACEMENT OF ELECTRICAL LEAD INSIDE HEART 有权
    电子导管内心放置方法及系统

    公开(公告)号：US20100042110A1

    公开(公告)日：2010-02-18

    申请号：US12570390

    申请日：2009-09-30

    申请人： James F. Kelley ,  Zhongping C. Yang ,  Mark T. Stewart

    发明人： James F. Kelley ,  Zhongping C. Yang ,  Mark T. Stewart

    IPC分类号： A61B17/00

    CPC分类号： A61N1/059 ,  A61B17/12 ,  A61B17/12009 ,  A61B17/128 ,  A61B17/3468 ,  A61B2017/00247 ,  A61B2017/12018 ,  A61B2018/00392

    摘要： A method of placing an electrical lead of an implantable cardiac device inside a heart of a patient. The method includes securing a tool to an atrial appendage of the heart to hold onto the atrial appendage, piercing the atrial appendage, and creating an aperture in the atrial appendage while holding the atrial appendage with the tool. The method also includes moving a distal end of the electrical lead into the heart through the aperture in the atrial appendage and into a ventricle of the heart. Furthermore, the method includes coupling the distal end of the electrical lead to cardiac tissue in the ventricle and delivering an electrical signal to the cardiac tissue in the ventricle of the heart to maintain a predetermined heartbeat of the heart.

    摘要翻译： 将可植入心脏装置的电引线放置在患者心脏内的方法。 该方法包括将工具固定到心脏的心房附着物，以固定在心房附近，刺穿心房附件，以及在用该工具持有心房附件的同时创建心房附近的孔。 该方法还包括通过心耳中的孔将电引线的远端移动到心脏中并进入心脏的心室。 此外，该方法包括将电导线的远端耦合到心室中的心脏组织，并将电信号传送到心脏心室的心脏组织以维持心脏的预定心跳。

    ELECTRODE ASSEMBLY IN A MEDICAL ELECTRICAL LEAD
    6.
    发明申请
    ELECTRODE ASSEMBLY IN A MEDICAL ELECTRICAL LEAD 有权
    医用电线中的电极组件

    公开(公告)号：US20110118813A1

    公开(公告)日：2011-05-19

    申请号：US12915631

    申请日：2010-10-29

    申请人： Zhongping C. Yang ,  Piotr J. Przybyszewski ,  Ben W. Herberg ,  Kevin R. Seifert ,  Dina L. Williams

    发明人： Zhongping C. Yang ,  Piotr J. Przybyszewski ,  Ben W. Herberg ,  Kevin R. Seifert ,  Dina L. Williams

    IPC分类号： A61N1/05

    CPC分类号： A61N1/375 ,  A61N1/05 ,  A61N1/086 ,  A61N1/3718

    摘要： A medical device lead is presented that includes an electrode assembly having a first electrode located near a distal end of the electrode assembly and a second electrode located near a proximal end of the electrode assembly. The electrode assembly also includes a conductive elongated coupler that is electrically coupled to the first electrode and capacitively coupled to the second electrode. At low frequencies and DC (e.g., during delivery of stimulation therapy), the capacitive coupling between the conductive elongated coupler and the second electrode presents a high impedance allowing little current to be redirected from the first electrode to the second electrode. However, at high frequencies (e.g., during an MRI scan) the capacitive coupling between the conductive elongated coupler and the second electrode presents a low impedance, resulting in a significant amount of induced current being redirected to the second electrode and dissipated into bodily fluid surrounding the second electrode.

    摘要翻译： 提供了一种医疗装置引线，其包括具有位于电极组件的远端附近的第一电极的电极组件和位于电极组件的近端附近的第二电极。 电极组件还包括电耦合到第一电极并电容耦合到第二电极的导电细长耦合器。 在低频和DC（例如，在递送刺激疗法期间），导电细长耦合器和第二电极之间的电容耦合呈现高阻抗，允许将电流从第一电极重定向到第二电极。 然而，在高频（例如，在MRI扫描期间），导电细长耦合器和第二电极之间的电容耦合呈现低阻抗，导致大量的感应电流被重定向到第二电极并且耗散到周围的体液中 第二电极。

    Electrode assembly in a medical electrical lead
    8.
    发明授权
    Electrode assembly in a medical electrical lead 有权
    医用电极中的电极组件

    公开(公告)号：US09014815B2

    公开(公告)日：2015-04-21

    申请号：US12915631

    申请日：2010-10-29

    申请人： Zhongping C. Yang ,  Piotr J. Przybyszewski ,  Ben W. Herberg ,  Kevin R. Seifert ,  Dina L. Williams

    发明人： Zhongping C. Yang ,  Piotr J. Przybyszewski ,  Ben W. Herberg ,  Kevin R. Seifert ,  Dina L. Williams

    IPC分类号： A61N1/05 ,  A61N1/375 ,  A61N1/37 ,  A61N1/08

    CPC分类号： A61N1/375 ,  A61N1/05 ,  A61N1/086 ,  A61N1/3718

    摘要： A medical device lead is presented that includes an electrode assembly having a first electrode located near a distal end of the electrode assembly and a second electrode located near a proximal end of the electrode assembly. The electrode assembly also includes a conductive elongated coupler that is electrically coupled to the first electrode and capacitively coupled to the second electrode. At low frequencies and DC (e.g., during delivery of stimulation therapy), the capacitive coupling between the conductive elongated coupler and the second electrode presents a high impedance allowing little current to be redirected from the first electrode to the second electrode. However, at high frequencies (e.g., during an MRI scan) the capacitive coupling between the conductive elongated coupler and the second electrode presents a low impedance, resulting in a significant amount of induced current being redirected to the second electrode and dissipated into bodily fluid surrounding the second electrode.

    摘要翻译： 提供了一种医疗装置引线，其包括具有位于电极组件的远端附近的第一电极的电极组件和位于电极组件的近端附近的第二电极。 电极组件还包括电耦合到第一电极并电容耦合到第二电极的导电细长耦合器。 在低频和DC（例如，在递送刺激疗法期间），导电细长耦合器和第二电极之间的电容耦合呈现高阻抗，允许将电流从第一电极重定向到第二电极。 然而，在高频（例如，在MRI扫描期间），导电细长耦合器和第二电极之间的电容耦合呈现低阻抗，导致大量的感应电流被重定向到第二电极并且耗散到周围的体液中 第二电极。

    MEDICAL ELECTRICAL LEAD HAVING BIOLOGICAL SURFACE AND METHODS OF MAKING AND USING SAME
    9.
    发明申请
    MEDICAL ELECTRICAL LEAD HAVING BIOLOGICAL SURFACE AND METHODS OF MAKING AND USING SAME 有权
    具有生物表面的医用电线及其制造和使用方法

    公开(公告)号：US20120165913A1

    公开(公告)日：2012-06-28

    申请号：US12977655

    申请日：2010-12-23

    申请人： Zhongping C. Yang

    发明人： Zhongping C. Yang

    IPC分类号： A61N1/05 ,  B05D5/00

    CPC分类号： A61N1/056

    摘要： An implantable electrical lead suitable for left sided cardiac placement, the implantable medical electrical lead having an external blood contacting surface having an external coating including a monolayer of at least one biological agent that promotes endothelialization covalently attached to a polymeric lead surface.

    摘要翻译： 一种适于左侧心脏放置的可植入电线，所述可植入医用电线具有外部血液接触表面，所述外部血液接触表面具有外部涂层，所述外部涂层包括促进共价连接至聚合物引线表面的内皮细胞的至少一种生物试剂的单层。