公开(公告)号：US11940413B2

公开(公告)日：2024-03-26

申请号：US17194850

申请日：2021-03-08

申请人： IsoPlexis Corporation

发明人： Steven Gordon ,  Thomas Hagerott ,  Edmund Golaski ,  Jerzy Olejnik

IPC分类号： C12Q1/68 ,  B01L3/00 ,  C12Q1/6869 ,  G01N27/447

CPC分类号： G01N27/44791 ,  B01L3/502761 ,  C12Q1/6869 ,  G01N27/44726 ,  B01L3/502715 ,  B01L2200/0668 ,  B01L2300/0877 ,  B01L2400/0487

摘要： The invention provides methods and compositions, including, without limitation, algorithms, computer readable media, computer programs, apparatus, and systems for determining the identity of nucleic acids in nucleotide sequences using, for example, data obtained from sequencing by synthesis methods. A plurality of smaller flow cells is employed, each with a relatively small area to be imaged, in order to provide greater flexibility and efficiency.

公开(公告)号：US11149309B2

公开(公告)日：2021-10-19

申请号：US15695548

申请日：2017-09-05

申请人： IsoPlexis Corporation

发明人： Steven Gordon ,  Daniel Stetson

IPC分类号： C12Q1/6874 ,  B01L3/00 ,  C12Q1/6837 ,  C12Q1/686 ,  C12Q1/6869 ,  C40B50/06 ,  B01L7/00

摘要： The present invention relates to methods and devices for amplifying nucleic acid, and, in particular, amplifying so as to generate products on a surface without the use of emulsions. In a preferred embodiment, a plurality of groups of amplified product are generated on the surface, each group positioned in different (typically predetermined) locations on said surface so as to create an array.