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公开(公告)号：US20210307662A1
公开(公告)日：2021-10-07
申请号：US17099697
申请日：2020-11-16
IPC分类号： A61B5/15 , A61B5/151 , A61B5/155 , A61B5/145 , A61B5/1486 , A61B5/00 , G01N21/03 , A61B5/157 , A61B5/1468 , G01N1/14 , G01N21/77 , G01N27/416
摘要： An arrangement for producing a sample of body fluid from a wound opening created in a skin surface at a sampling site includes at least one skin-penetration member having a first end configured to pierce the surface of the skin, and a inner lumen in communication with the first end; at least one actuator operatively associated with the at least one skin-penetration member; and at least one catalyst device configured to cause perfusion of body fluid at the sampling site; wherein the at least one actuator is configured to locate the at least one skin-penetration member so as to obstruct the wound opening while transporting body fluid through the inner lumen. Associated methods are also described.
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公开(公告)号：US20180214059A1
公开(公告)日：2018-08-02
申请号：US15826418
申请日：2017-11-29
发明人： Raul ESCUTIA , Craig M. LITHERLAND , Jeffrey L. EMERY , Jeffrey M. JONES , Michael F. TOMASCO , Kelley J. LIPMAN
CPC分类号： A61B5/150832 , A61B5/150022 , A61B5/150068 , A61B5/150076 , A61B5/150083 , A61B5/150091 , A61B5/150099 , A61B5/150183 , A61B5/150229 , A61B5/150259 , A61B5/150267 , A61B5/150274 , A61B5/150389 , A61B5/150412 , A61B5/150442 , A61B5/150748 , A61B5/150809 , A61B5/150816 , A61B5/150824 , A61B5/150954 , A61B5/150984 , A61B5/15107 , A61B5/15109 , A61B5/15117 , A61B5/15151 , A61B5/15161 , A61B5/157 , A61M5/422
摘要： An arrangement for producing a sample of body fluid from a wound opening created in a skin surface at a sampling site includes: a housing, the housing comprising a first opening; a skin interface member disposed in the first opening, the skin interface member comprising an inner member having a second opening, and an outer member at least partially surrounding the inner member and attached to the first opening; and at least one skin-penetration member configured and arranged to project within the second opening. Arrangements having alternatively constructed skin interface members are also described.
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公开(公告)号：US20240108259A1
公开(公告)日：2024-04-04
申请号：US18301741
申请日：2023-04-17
IPC分类号： A61B5/15 , A61B5/00 , A61B5/145 , A61B5/1468 , A61B5/1486 , A61B5/151 , A61B5/155 , A61B5/157 , G01N1/14 , G01N21/03 , G01N21/77 , G01N27/416
CPC分类号： A61B5/150984 , A61B5/1411 , A61B5/1427 , A61B5/14532 , A61B5/14546 , A61B5/1468 , A61B5/1486 , A61B5/150022 , A61B5/150068 , A61B5/150076 , A61B5/150083 , A61B5/150099 , A61B5/150167 , A61B5/150229 , A61B5/150343 , A61B5/150389 , A61B5/150396 , A61B5/150412 , A61B5/150946 , A61B5/150954 , A61B5/151 , A61B5/15111 , A61B5/15113 , A61B5/15117 , A61B5/15121 , A61B5/15123 , A61B5/15146 , A61B5/15148 , A61B5/15151 , A61B5/15161 , A61B5/15163 , A61B5/15186 , A61B5/155 , A61B5/157 , A61B5/681 , A61B5/6824 , A61B5/6828 , G01N1/14 , G01N21/0303 , G01N21/77 , G01N27/416 , A61B5/150969 , A61B2560/0443 , A61B2560/0462
摘要： An arrangement includes a housing, a plurality of sampling and analysis sites contained within the housing, each of the sampling and analysis sites having a skin-penetration member having a first end configured to pierce the skin, and an inner lumen in communication with the first end, an actuator operatively associated with the skin-penetration member, and an analyte quantification member in fluid communication with the inner lumen of the skin-penetration member. Integrated devices including such arrangements are also described.
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公开(公告)号：US20200155052A1
公开(公告)日：2020-05-21
申请号：US16568095
申请日：2019-09-11
IPC分类号： A61B5/15 , G01N27/416 , G01N21/77 , G01N1/14 , A61B5/1468 , A61B5/151 , A61B5/157 , A61B5/155 , G01N21/03 , A61B5/00 , A61B5/1486 , A61B5/145
摘要： An arrangement includes a housing, a plurality of sampling and analysis sites contained within the housing, each of the sampling and analysis sites having a skin-penetration member having a first end configured to pierce the skin, and an inner lumen in communication with the first end, an actuator operatively associated with the skin-penetration member, and an analyte quantification member in fluid communication with the inner lumen of the skin-penetration member. Integrated devices including such arrangements are also described.
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公开(公告)号：US20160367178A1
公开(公告)日：2016-12-22
申请号：US15191434
申请日：2016-06-23
IPC分类号： A61B5/15 , A61B5/1468 , A61B5/151 , G01N27/416 , A61B5/157 , A61B5/00 , G01N1/14 , G01N21/77 , A61B5/145 , A61B5/155
摘要： An arrangement includes a housing, a plurality of sampling and analysis sites contained within the housing, each of the sampling and analysis sites having a skin-penetration member having a first end configured to pierce the skin, and an inner lumen in communication with the first end, an actuator operatively associated with the skin-penetration member, and an analyte quantification member in fluid communication with the inner lumen of the skin-penetration member. Integrated devices including such arrangements are also described.
摘要翻译： 一种装置包括壳体，容纳在壳体内的多个采样和分析位置，每个采样和分析位置具有皮肤穿透构件，其具有构造成刺穿皮肤的第一端，以及与第一 与皮肤穿透构件可操作地相关联的致动器以及与皮肤穿透构件的内腔流体连通的分析物定量构件。 还描述了包括这种布置的集成设备。
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公开(公告)号：US20140336480A1
公开(公告)日：2014-11-13
申请号：US14446262
申请日：2014-07-29
CPC分类号： A61B5/150984 , A61B5/1411 , A61B5/1427 , A61B5/14532 , A61B5/14546 , A61B5/1468 , A61B5/1486 , A61B5/150022 , A61B5/150068 , A61B5/150076 , A61B5/150083 , A61B5/150099 , A61B5/150167 , A61B5/150229 , A61B5/150343 , A61B5/150389 , A61B5/150396 , A61B5/150412 , A61B5/150946 , A61B5/150954 , A61B5/150969 , A61B5/151 , A61B5/15111 , A61B5/15113 , A61B5/15117 , A61B5/15121 , A61B5/15123 , A61B5/15146 , A61B5/15148 , A61B5/15151 , A61B5/15161 , A61B5/15163 , A61B5/15186 , A61B5/155 , A61B5/157 , A61B5/681 , A61B5/6824 , A61B5/6828 , A61B2560/0443 , A61B2560/0462 , G01N1/14 , G01N21/0303 , G01N21/77 , G01N27/416
摘要： An arrangement for producing a sample of body fluid from a wound opening created in a skin surface at a sampling site includes at least one skin-penetration member having a first end configured to pierce the surface of the skin, and a inner lumen in communication with the first end; at least one actuator operatively associated with the at least one skin-penetration member; and at least one catalyst device configured to cause perfusion of body fluid at the sampling site; wherein the at least one actuator is configured to locate the at least one skin-penetration member so as to obstruct the wound opening while transporting body fluid through the inner lumen. Associated methods are also described.
摘要翻译： 用于从在采样部位的皮肤表面产生的伤口开口产生体液样本的装置包括至少一个皮肤穿透部件，其具有构造成刺穿皮肤表面的第一端和与皮肤表面连通的内腔 第一端 与所述至少一个皮肤穿透构件可操作地相关联的至少一个致动器; 以及至少一个催化剂装置，其构造成在取样部位引起体液灌注; 其中所述至少一个致动器构造成定位所述至少一个皮肤穿透构件，以便在将体液输送通过所述内腔时阻塞所述伤口的开口。 还描述了相关方法。
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公开(公告)号：US20180310865A1
公开(公告)日：2018-11-01
申请号：US15829835
申请日：2017-12-01
IPC分类号： A61B5/15 , G01N27/416 , G01N21/03 , G01N1/14 , G01N21/77 , A61B5/155 , A61B5/145 , A61B5/00 , A61B5/157 , A61B5/151 , A61B5/1486 , A61B5/1468
CPC分类号： A61B5/150984 , A61B5/1411 , A61B5/1427 , A61B5/14532 , A61B5/14546 , A61B5/1468 , A61B5/1486 , A61B5/150022 , A61B5/150068 , A61B5/150076 , A61B5/150083 , A61B5/150099 , A61B5/150167 , A61B5/150229 , A61B5/150343 , A61B5/150389 , A61B5/150396 , A61B5/150412 , A61B5/150946 , A61B5/150954 , A61B5/150969 , A61B5/151 , A61B5/15111 , A61B5/15113 , A61B5/15117 , A61B5/15121 , A61B5/15123 , A61B5/15146 , A61B5/15148 , A61B5/15151 , A61B5/15161 , A61B5/15163 , A61B5/15186 , A61B5/155 , A61B5/157 , A61B5/681 , A61B5/6824 , A61B5/6828 , A61B2560/0443 , A61B2560/0462 , G01N1/14 , G01N21/0303 , G01N21/77 , G01N27/416
摘要： An arrangement for producing a sample of body fluid from a wound opening created in a skin surface at a sampling site includes at least one skin-penetration member having a first end configured to pierce the surface of the skin, and a inner lumen in communication with the first end; at least one actuator operatively associated with the at least one skin-penetration member; and at least one catalyst device configured to cause perfusion of body fluid at the sampling site; wherein the at least one actuator is configured to locate the at least one skin-penetration member so as to obstruct the wound opening while transporting body fluid through the inner lumen. Associated methods are also described.
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公开(公告)号：US20160038066A1
公开(公告)日：2016-02-11
申请号：US14743867
申请日：2015-06-18
CPC分类号： A61B5/150984 , A61B5/1411 , A61B5/1427 , A61B5/14532 , A61B5/14546 , A61B5/1468 , A61B5/1486 , A61B5/150022 , A61B5/150068 , A61B5/150076 , A61B5/150083 , A61B5/150099 , A61B5/150167 , A61B5/150229 , A61B5/150343 , A61B5/150389 , A61B5/150396 , A61B5/150412 , A61B5/150946 , A61B5/150954 , A61B5/150969 , A61B5/151 , A61B5/15111 , A61B5/15113 , A61B5/15117 , A61B5/15121 , A61B5/15123 , A61B5/15146 , A61B5/15148 , A61B5/15151 , A61B5/15161 , A61B5/15163 , A61B5/15186 , A61B5/155 , A61B5/157 , A61B5/681 , A61B5/6824 , A61B5/6828 , A61B2560/0443 , A61B2560/0462 , G01N1/14 , G01N21/0303 , G01N21/77 , G01N27/416
摘要： An arrangement for producing a sample of body fluid from an opening created in a skin surface at a sampling site including a cartridge with a plurality of compartments and a plurality of sampling sites, and a detector assembly. Each sampling site includes a skin-penetration member having a first end configured to pierce the surface of the skin and an inner lumen in communication with the first end, a spring actuator operatively associated with the skin-penetration member, and a needle hub connecting the skin-penetration member and the spring actuator. The needle hub includes a reagent pad and the spring actuator is configured to drive the skin-penetration member to form the wound opening. Each compartment at least partially encloses the skin-penetration member, the spring actuator, and the needle hub of a respective sampling site.
摘要翻译： 一种用于从包括具有多个隔室和多个取样位置的盒的取样部位处的皮肤表面中产生的开口产生体液样品的装置和检测器组件。 每个采样部位包括皮肤穿透构件，其具有构造成刺穿皮肤表面的第一端和与第一端连通的内腔，与皮肤穿透构件可操作地相关联的弹簧致动器和连接 皮肤穿透构件和弹簧致动器。 针座包括试剂垫，并且弹簧致动器构造成驱动皮肤穿透构件以形成伤口。 每个隔室至少部分地包围相应取样部位的皮肤穿透构件，弹簧致动器和针座。
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公开(公告)号：US20130144189A1
公开(公告)日：2013-06-06
申请号：US13752261
申请日：2013-01-28
IPC分类号： A61B5/151
CPC分类号： A61B5/150984 , A61B5/1411 , A61B5/1427 , A61B5/14532 , A61B5/14546 , A61B5/1468 , A61B5/1486 , A61B5/150022 , A61B5/150068 , A61B5/150076 , A61B5/150083 , A61B5/150099 , A61B5/150167 , A61B5/150229 , A61B5/150343 , A61B5/150389 , A61B5/150396 , A61B5/150412 , A61B5/150946 , A61B5/150954 , A61B5/150969 , A61B5/151 , A61B5/15111 , A61B5/15113 , A61B5/15117 , A61B5/15121 , A61B5/15123 , A61B5/15146 , A61B5/15148 , A61B5/15151 , A61B5/15161 , A61B5/15163 , A61B5/15186 , A61B5/155 , A61B5/157 , A61B5/681 , A61B5/6824 , A61B5/6828 , A61B2560/0443 , A61B2560/0462 , G01N1/14 , G01N21/0303 , G01N21/77 , G01N27/416
摘要： An arrangement for producing a sample of body fluid from a wound opening created in a skin surface at a sampling site includes at least one skin-penetration member having a first end configured to pierce the surface of the skin, and a inner lumen in communication with the first end; at least one actuator operatively associated with the at least one skin-penetration member; and at least one catalyst device configured to cause perfusion of body fluid at the sampling site; wherein the at least one actuator is configured to locate the at least one skin-penetration member so as to obstruct the wound opening while transporting body fluid through the inner lumen. Associated methods are also described.
摘要翻译： 用于从在采样部位的皮肤表面产生的伤口开口产生体液样本的装置包括至少一个皮肤穿透部件，其具有构造成刺穿皮肤表面的第一端和与皮肤表面连通的内腔 第一端 与所述至少一个皮肤穿透构件可操作地相关联的至少一个致动器; 以及至少一个催化剂装置，其构造成在取样部位引起体液灌注; 其中所述至少一个致动器构造成定位所述至少一个皮肤穿透构件，以便在将体液输送通过所述内腔时阻塞所述伤口的开口。 还描述了相关方法。
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