公开(公告)号：US11592421B2

公开(公告)日：2023-02-28

申请号：US16616339

申请日：2018-05-22

Applicant: Integenx Inc.

Inventor： Mattias Vangbo ,  David King ,  Arnaldo Barican

IPC: G01N27/447 ,  C12Q1/6806 ,  C12Q1/686

Abstract: Disclosed are methods for performing capillary electrophoresis on two or more nucleic acid samples. The methods employ a forward voltage to move a first sample forward from an inlet to an interrogation region in the capillary, then a backward voltage to move the first sample backward, and then a forward voltage again to move the first sample and a second sample forward. Systems and apparatuses for performing capillary electrophoresis are also provided.

公开(公告)号：US20210021670A1

公开(公告)日：2021-01-21

申请号：US17039647

申请日：2020-09-30

Applicant: IntegenX Inc.

Inventor： Robert A. Schueren ,  David King ,  Chungsoo Charles Park ,  Arnaldo Barican ,  Charles David Troup

IPC: H04L29/08 ,  G01N27/447 ,  G16B40/00 ,  G16B50/40 ,  G06F3/01

Abstract: A command center includes at least one network communications interface configured for two-way communications with a plurality of sites remote from the command center and at least one display screen and user interface. Each of the plurality of sites includes at least one forensic field test device configured to identify individuals using DNA samples from the individuals. The display screen and user interface are configured to depict aspects of forensic field test devices of the plurality of sites, wherein the aspects include a site identifier for each of the forensic field test devices and one or more additional aspects.

公开(公告)号：US10855748B2

公开(公告)日：2020-12-01

申请号：US15910743

申请日：2018-03-02

Applicant: IntegenX Inc.

Inventor： Robert A. Schueren ,  David King ,  Chungsoo Charles Park ,  Arnaldo Barican ,  Charles David Troup

IPC: H04L29/08 ,  G01N27/447 ,  G16B40/00 ,  G16B50/40 ,  G06F3/01 ,  G06F3/0481

Abstract: A command center includes at least one network communications interface configured for two-way communications with a plurality of sites remote from the command center and at least one display screen and user interface. Each of the plurality of sites includes at least one forensic field test device configured to identify individuals using DNA samples from the individuals. The display screen and user interface are configured to depict aspects of forensic field test devices of the plurality of sites, wherein the aspects include a site identifier for each of the forensic field test devices and one or more additional aspects.

公开(公告)号：US20230152274A1

公开(公告)日：2023-05-18

申请号：US18157274

申请日：2023-01-20

Applicant: IntegenX, Inc.

Inventor： Mattias Vangbo ,  David King ,  Arnaldo Barican

IPC: G01N27/447 ,  C12Q1/6806 ,  C12Q1/686

CPC classification number: G01N27/44713 ,  C12Q1/6806 ,  C12Q1/686 ,  G01N27/44791 ,  C12Q2565/125 ,  G01N27/44721

Abstract: A system for performing capillary electrophoresis of multiple samples comprises a capillary containing a separation medium and having inlet and distal ends and an interrogation region; a power source configured to apply voltages between inlet and distal ends; and logic to cause execution of: applying a first substantially constant forward polarity electrophoresis voltage to the capillary; before all of the first DNA fragments have passed the interrogation region, applying a reverse polarity voltage pulse to the capillary, thereby transporting at least some of the first DNA fragments in the capillary toward the capillary inlet; introducing a second sample to the capillary inlet, the second sample comprising second DNA fragments having a plurality of different sizes; and applying a second substantially constant forward polarity electrophoresis voltage to the capillary to simultaneously perform electrophoresis on the second DNA fragments and the first DNA fragments.

公开(公告)号：US20200158685A1

公开(公告)日：2020-05-21

申请号：US16616339

申请日：2018-05-22

Applicant: Integenx Inc.

Inventor： Mattias Vangbo ,  David King ,  Arnaldo Barican

IPC: G01N27/447 ,  C12Q1/6806 ,  C12Q1/686

Abstract: Disclosed are methods for performing capillary electrophoresis on two or more nucleic acid samples. The methods employ a forward voltage to move a first sample forward from an inlet to an interrogation region in the capillary, then a backward voltage to move the first sample backward, and then a forward voltage again to move the first sample and a second sample forward. Systems and apparatuses for performing capillary electrophoresis are also provided.

公开(公告)号：US20250060332A1

公开(公告)日：2025-02-20

申请号：US18935935

申请日：2024-11-04

Applicant: IntegenX Inc.

Inventor： Mattias Vangbo ,  David King ,  Arnaldo Barican

IPC: G01N27/447 ,  C12Q1/6806 ,  C12Q1/686

Abstract: A system for outputting electropherograms includes a capillary containing a separation medium and comprising an inlet end, a distal end, and an interrogation region between the inlet and distal ends, the inlet end of the capillary configured to receive a plurality of differing samples containing DNA fragments having a plurality of different sizes; a power source configured to selectively apply forward and reverse polarity voltages between the inlet end and the distal end of the capillary; a detector configured to detect signal associated with DNA fragments moving through the interrogation region of the capillary; and a processor communicatively coupled to the detector and configured to process signal detected by the detector and output electropherograms during an electrophoresis run, the electropherograms corresponding to a plurality of differing samples successively introduced to the capillary from the inlet and traveling through the capillary at the same time.

公开(公告)号：US12200042B2

公开(公告)日：2025-01-14

申请号：US17039647

申请日：2020-09-30

Applicant: IntegenX Inc.

Inventor： Robert A. Schueren ,  David King ,  Chungsoo Charles Park ,  Arnaldo Barican ,  Charles David Troup

IPC: H04L67/10 ,  G01N27/447 ,  G06F3/01 ,  G06F3/04817 ,  G16B20/20 ,  G16B40/00 ,  G16B40/10 ,  G16B50/40 ,  H04L67/306 ,  H04L67/50 ,  H04L67/52

Abstract: A command center includes at least one network communications interface configured for two-way communications with a plurality of sites remote from the command center and at least one display screen and user interface. Each of the plurality of sites includes at least one forensic field test device configured to identify individuals using DNA samples from the individuals. The display screen and user interface are configured to depict aspects of forensic field test devices of the plurality of sites, wherein the aspects include a site identifier for each of the forensic field test devices and one or more additional aspects.

公开(公告)号：US12135309B2

公开(公告)日：2024-11-05

申请号：US18157274

申请日：2023-01-20

Applicant: IntegenX, Inc.

Inventor： Mattias Vangbo ,  David King ,  Arnaldo Barican

IPC: G01N27/447 ,  C12Q1/6806 ,  C12Q1/686

Abstract: A system for performing capillary electrophoresis of multiple samples comprises a capillary containing a separation medium and having inlet and distal ends and an interrogation region; a power source configured to apply voltages between inlet and distal ends; and logic to cause execution of: applying a first substantially constant forward polarity electrophoresis voltage to the capillary; before all of the first DNA fragments have passed the interrogation region, applying a reverse polarity voltage pulse to the capillary, thereby transporting at least some of the first DNA fragments in the capillary toward the capillary inlet; introducing a second sample to the capillary inlet, the second sample comprising second DNA fragments having a plurality of different sizes; and applying a second substantially constant forward polarity electrophoresis voltage to the capillary to simultaneously perform electrophoresis on the second DNA fragments and the first DNA fragments.

公开(公告)号：US20180262557A1

公开(公告)日：2018-09-13

申请号：US15910743

申请日：2018-03-02

Applicant: IntegenX Inc.

Inventor： Robert A. Schueren ,  David King ,  Chungsoo Charles Park ,  Arnaldo Barican ,  Charles David Troup

IPC: H04L29/08 ,  G01N27/447 ,  G06F19/24

CPC classification number: H04L67/10 ,  G01N27/447 ,  G01N27/44704 ,  G06F3/04817 ,  G16B40/00 ,  G16B50/40 ,  H04L67/18 ,  H04L67/22 ,  H04L67/306

Abstract: A command center includes at least one network communications interface configured for two-way communications with a plurality of sites remote from the command center and at least one display screen and user interface. Each of the plurality of sites includes at least one forensic field test device configured to identify individuals using DNA samples from the individuals. The display screen and user interface are configured to depict aspects of forensic field test devices of the plurality of sites, wherein the aspects include a site identifier for each of the forensic field test devices and one or more additional aspects.