公开(公告)号：US10401974B2

公开(公告)日：2019-09-03

申请号：US15266175

申请日：2016-09-15

申请人： Industry-Academic Cooperation Foundation, Yonsei University

发明人： Woo Young Shim ,  Tae Yoon Lee ,  Kil Soo Lee ,  Jae Hong Lee ,  Dae Eun Kim

IPC分类号： G06F3/02 ,  G09G5/00 ,  G06F3/023 ,  G06F3/041 ,  G06F3/044 ,  G01L1/14 ,  G06F3/047 ,  H03K17/96 ,  G06F3/0488 ,  G06F3/0354

摘要： Provided is a highly sensitive pressure sensor that includes a lower substrate on which a first electrode having surface roughness is formed; an upper substrate on which a second electrode having surface roughness is formed; and a dielectric material stacked between the lower substrate and the upper substrate to be disposed between the first electrode and the second electrode.

公开(公告)号：US10246676B2

公开(公告)日：2019-04-02

申请号：US15414031

申请日：2017-01-24

申请人： INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY

发明人： Tae Yoon Lee ,  Hee Tak Han ,  Jung Mok Seo ,  Se Ra Shin ,  Hyun Chul Kim

IPC分类号： C12M1/00 ,  C12M1/26 ,  C12M1/32 ,  C12M1/42

摘要： Disclosed is a cell stimulation apparatus. In particular, a cell stimulation apparatus according to an embodiment of the present disclosure includes a cell containment part in which at least one cell containment groove containing cells is formed; and a pressure control part that supports the cell containment part and transforms the at least one cell containment groove by applying pressure to the cell containment part, wherein a bottom of the at least one cell containment groove is made of a flexible material.

公开(公告)号：US09908117B2

公开(公告)日：2018-03-06

申请号：US14861677

申请日：2015-09-22

申请人： INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIVERSITY

发明人： Hyo Il Jung ,  Kyung-A Hyun ,  Tae Yoon Lee

IPC分类号： B01L3/00 ,  G01N15/06 ,  G01N33/00 ,  G01N33/48 ,  G01N33/543 ,  G01N33/50 ,  G01N33/569 ,  B01F5/06 ,  B01F13/00

CPC分类号： B01L3/502761 ,  B01F5/0647 ,  B01F5/0655 ,  B01F13/0059 ,  B01L3/502707 ,  B01L3/5085 ,  B01L2200/0652 ,  B01L2200/0668 ,  B01L2300/044 ,  B01L2300/0858 ,  B01L2300/0883 ,  B01L2400/0409 ,  B01L2400/043 ,  G01N33/5002 ,  G01N33/54326 ,  G01N33/5434 ,  G01N33/54346 ,  G01N33/56972 ,  G01N2333/70589

摘要： The present invention relates to a microfluidic separation device, a separation method using the same and a kit for separating circulating rare cells from blood using the same, and more particularly, to a microfluidic-based separation technology for fixing target particles of a sample, which have a specific affinity for magnetic nanoparticles, to a device by use of a magnetic material, and for isolating the sample from which the target particles have been removed. The present invention may be effectively applied to remove leukocytes from a blood sample in order to isolate circulating rare cells (CRCs), particularly circulating tumor cells (CTCs).