公开(公告)号：US20160341727A1

公开(公告)日：2016-11-24

申请号：US14994042

申请日：2016-01-12

Applicant: ISIS INNOVATION LIMITED

Inventor： Graham Ogg ,  Li-Chieh Huang ,  Aamir Aslam

IPC: G01N33/569 ,  G01N33/543

CPC classification number: G01N33/56977 ,  C07K17/00 ,  C12N15/1055 ,  G01N33/54313 ,  G01N33/56972 ,  G01N2333/7051 ,  G01N2333/70539

Abstract: A method to identify a peptide and/or its encoding DNA, wherein the peptide binds to a T-cell receptor and/or an NK-cell receptor and/or an NKT-cell receptor, the method comprising: providing a carrier to which is attached a peptide and its encoding DNA; providing an MHC and/or an MHC-like molecule; and exposing the peptide to a T-cell receptor and/or an NK-cell receptor and/or an NKT-cell receptor in the presence of the MHC or MHC-like molecule.