-
公开(公告)号：US20170137439A1
公开(公告)日：2017-05-18
申请号：US15406994
申请日：2017-01-16
Applicant: Ironwood Pharmaceuticals, Inc.
Inventor： Takashi NAKAI , Joel MOORE , Nicholas Robert PERL , Rajesh R. IYENGAR , Ara MERMERIAN , G-Yoon Jamie IM , Thomas Wai-Ho LEE , Colleen HUDSON , Glen Robert RENNIE , James JIA , Paul Allan RENHOWE , Timothy Claude BARDEN , Xiang Y. YU , James Edward SHEPPECK , Karthik IYER , Joon JUNG , George Todd MILNE , Kimberly Kafadar LONG , Mark G. CURRIE
IPC: C07D498/04 , A61K31/506 , A61K31/5377 , C07D487/04 , C07D491/107 , C07D471/10 , C07D487/10 , C07D417/14 , A61K31/541 , A61K31/55 , C07D451/02 , C07D471/04 , C07D401/14 , C07D403/04 , A61K31/517 , A61K31/519 , C07D413/14
CPC classification number: A61K31/506 , A61K31/517 , A61K31/519 , A61K31/5377 , A61K31/541 , A61K31/55 , A61K45/06 , C07D401/14 , C07D403/04 , C07D413/14 , C07D417/14 , C07D451/02 , C07D471/04 , C07D471/08 , C07D471/10 , C07D487/04 , C07D487/10 , C07D491/107 , C07D495/04 , C07D498/04 , Y02A50/423
Abstract: Compounds of Formulae I′ and I are described, which are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds are also useful for treating, preventing or managing various disorders that are herein disclosed.
-
公开(公告)号：US20160031903A1
公开(公告)日：2016-02-04
申请号：US14775954
申请日：2014-03-14
Applicant: IRONWOOD PHARMACEUTICALS, INC.
Inventor： Takashi NAKAI , Joel MOORE , Nicholas Robert PERL , Rajesh R. IYENGAR , Ara MERMERIAN , G-Yoon Jamie IM , Thomas Wai-Ho LEE , Colleen HUDSON , Glen Robert RENNIE , James JIA , Paul Allan RENHOWE , Timothy Claude BARDEN , Xiang Y. YU , James Edward SHEPPECK , Karthik IYER , Joon JUNG , George Todd MILNE , Kimberly Kafadar LONG
IPC: C07D498/04 , C07D487/04 , C07D417/14 , C07D491/107 , C07D471/04 , C07D413/14 , C07D487/10
CPC classification number: A61K31/506 , A61K31/517 , A61K31/519 , A61K31/5377 , A61K31/541 , A61K31/55 , A61K45/06 , C07D401/14 , C07D403/04 , C07D413/14 , C07D417/14 , C07D451/02 , C07D471/04 , C07D471/08 , C07D471/10 , C07D487/04 , C07D487/10 , C07D491/107 , C07D495/04 , C07D498/04
Abstract: Compounds of Formulae I′ and I are described, which are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds are also useful for treating, preventing or managing various disorders that are herein disclosed.
-
公开(公告)号：US20160375022A1
公开(公告)日：2016-12-29
申请号：US15245697
申请日：2016-08-24
Applicant: Ironwood Pharmaceuticals, Inc.
Inventor： Takashi NAKAI , Joel MOORE , Nicholas Robert PERL , Rajesh R. IYENGAR , Ara MERMERIAN , G-Yoon Jamie IM , Thomas Wai-Ho LEE , Colleen HUDSON , Glen Robert RENNIE , James JIA , Paul Allan RENHOWE , Timothy Claude BARDEN , Xiang Y. YU , James Edward SHEPPECK , Karthik IYER , Joon JUNG , George Todd MILNE , Kimberly Kafadar LONG , Mark G. CURRIE
IPC: A61K31/506 , A61K45/06
CPC classification number: A61K31/506 , A61K31/517 , A61K31/519 , A61K31/5377 , A61K31/541 , A61K31/55 , A61K45/06 , C07D401/14 , C07D403/04 , C07D413/14 , C07D417/14 , C07D451/02 , C07D471/04 , C07D471/08 , C07D471/10 , C07D487/04 , C07D487/10 , C07D491/107 , C07D495/04 , C07D498/04 , Y02A50/423
Abstract: Compounds of Formulae I′ and I are described, which are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds are also useful for treating, preventing or managing various disorders that are herein disclosed.
-
公开(公告)号：US20150342954A1
公开(公告)日：2015-12-03
申请号：US14824689
申请日：2015-08-12
Applicant: IRONWOOD PHARMACEUTICALS, INC.
Inventor： Charles KIM , Takashi NAKAI , Joel MOORE , Nicholas Robert PERL , G-Yoon Jamie IM , Timothy Claude BARDEN , Rajesh R. IYENGAR , Daniel P. ZIMMER , Angelika FRETZEN , Paul Allan RENHOWE
IPC: A61K31/52 , A61K45/06 , A61K31/4439 , A61K31/519 , A61K31/506 , A61K31/513
CPC classification number: A61K31/52 , A61K31/4439 , A61K31/506 , A61K31/513 , A61K31/519 , A61K45/06 , C07D403/04 , C07D413/14 , C07D417/14 , C07D473/00 , C07D487/04 , C07D513/22 , Y02A50/423
Abstract: Compound of Table I are described. They are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds may be useful for treating, preventing or managing various disorders that are herein disclosed.
-
公开(公告)号：US20180155345A1
公开(公告)日：2018-06-07
申请号：US15511888
申请日：2015-09-16
Applicant: IRONWOOD PHARMACEUTICALS, INC.
Inventor： Glen Robert RENNIE , Nicholas PERL , Ara MERMERIAN , Joon JUNG , James JIA , Rajesh R. IYENGAR , G-Yoon Jamie IM , Timothy Claude BARDEN , James Edward SHEPPECK , Paul Allan RENHOWE , Takashi NAKAI , Thomas Wai-Ho LEE , Karthik IYER
IPC: C07D487/04 , C07D498/04 , A61P9/10 , A61P15/00 , A61P29/00
CPC classification number: C07D487/04 , A61P9/10 , A61P15/00 , A61P29/00 , C07D401/04 , C07D401/14 , C07D405/14 , C07D413/14 , C07D417/14 , C07D498/04
Abstract: The present patent application discloses at least the compounds according to Formula I′ shown below, or pharmaceutically acceptable salts thereof, wherein ring D, ring A, ring E, JB, n, JD, J, X, Z, Z1, RC1, RC2, Y, R9, o and W are as defined herein.
-
Patent Agency Ranking
公开(公告)号：US20170298055A1
公开(公告)日：2017-10-19
申请号：US15511891
申请日：2015-09-16
Applicant: IRONWOOD PHARMACEUTICALS, INC.
Inventor： Glen Robert RENNIE , Nicholas PERL , Thomas Wai-Ho LEE , Paul Allan RENHOWE , Takashi NAKAI , Ara MERMERIAN , G-Yoon Jamie IM
IPC: C07D413/14
CPC classification number: C07D413/14 , C07D401/04 , C07D401/14 , C07D405/14 , C07D417/14
Abstract: The present patent application discloses at least the compounds according to Formula Ia and Formula Ib shown below, or pharmaceutically acceptable salts thereof, wherein ring D, ring A, JB, n, J, RC1, RC2, Z1, Z2, W, X, Y1, Y2, JF and R9 are as defined herein.
-
公开(公告)号：US20160175307A1
公开(公告)日：2016-06-23
申请号：US15054448
申请日：2016-02-26
Applicant: Ironwood Pharmaceuticals, Inc.
Inventor： G-Yoon Jamie IM , Rajesh IYENGAR , Joel MOORE , Angelika FRETZEN
IPC: A61K31/513 , A61K45/06 , A61K31/506
CPC classification number: A61K31/513 , A61K31/506 , A61K45/06 , C07D407/14 , C07D409/14 , C07D413/14
Abstract: Compounds of Formula I are described. They are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds may be useful for treating, preventing or managing various disorders that are herein disclosed.
-
公开(公告)号：US20190284168A1
公开(公告)日：2019-09-19
申请号：US16165192
申请日：2018-10-19
Applicant: IRONWOOD PHARMACEUTICALS, INC.
Inventor： Timothy Claude BARDEN , James Edward SHEPPECK , Glen Robert RENNIE , Paul Allan RENHOWE , Nicholas PERL , Takashi NAKAI , Ara MERMERIAN , Thomas Wai-Ho LEE , Joon JUNG , James JIA , Karthik IYER , Rajesh R. IYENGAR , G-Yoon Jamie IM
IPC: C07D403/04 , C07D491/107 , C07D495/04 , C07D491/10 , C07D401/14 , C07D417/14 , C07D403/14 , C07D413/14 , C07D487/04
Abstract: Compounds are described, which are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds are also useful for treating, preventing or managing various disorders that are herein disclosed.
-
公开(公告)号：US20170291889A1
公开(公告)日：2017-10-12
申请号：US15511900
申请日：2015-09-16
Applicant: IRONWOOD PHARMACEUTICALS, INC.
Inventor： Timothy Claude BARDEN , James Edward SHEPPECK , Glen Robert RENNIE , Paul Allan RENHOWE , Nicholas PERL , Takashi NAKAI , Ara MERMERIAN , Thomas Wai-Ho LEE , Joon JUNG , James JIA , Karthik IYER , Rajesh R. IYENGAR , G-Yoon Jamie IM
IPC: C07D403/04 , C07D403/14 , C07D491/107 , C07D417/14 , C07D487/04 , C07D413/14 , C07D495/04
CPC classification number: C07D403/04 , C07D401/14 , C07D403/14 , C07D413/14 , C07D417/14 , C07D487/04 , C07D491/10 , C07D491/107 , C07D495/04
Abstract: Compounds are described, which are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds are also useful for treating, preventing or managing various disorders that are herein disclosed.
-
公开(公告)号：US20170136019A1
公开(公告)日：2017-05-18
申请号：US15406959
申请日：2017-01-16
Applicant: Ironwood Pharmaceuticals, Inc.
Inventor： Takashi NAKAI , Joel MOORE , Nicholas Robert PERL , Rajesh R. IYENGAR , Ara MERMERIAN , G-Yoon Jamie IM , Thomas Wai-Ho LEE , Colleen HUDSON , Glen Robert RENNIE , James JIA , Paul Allan RENHOWE , Timothy Claude BARDEN , Xiang Y. YU , James Edward SHEPPECK , Karthik IYER , Joon JUNG , George Todd MILNE , Kimberly Kafadar LONG , Mark G. CURRIE
IPC: A61K31/506 , A61K45/06
Abstract: Compounds of Formulae I′ and I are described, which are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds are also useful for treating, preventing or managing various disorders that are herein disclosed.
-
-
-
-
-
-
-
-
-
Search Results
11
records
(took 0.037 seconds)
