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    HIGH HYDROGEN UTILIZATION AND GAS RECYCLE
    2.
    发明申请
    HIGH HYDROGEN UTILIZATION AND GAS RECYCLE 审中-公开

    公开(公告)号：US20190316072A1

    公开(公告)日：2019-10-17

    申请号：US16372106

    申请日：2019-04-01

    申请人： INVISTA NORTH AMERICA S.A.R.L.

    发明人： Gary J. Smith ,  Paul S. Pearlman ,  Gregory S. Kirby

    IPC分类号： C12M1/00 ,  C12P7/62 ,  C12M1/34

    摘要： Provided herein are systems and methods for recycling and supplementing off-gas from a gas fed reaction process. The systems and methods are particularly useful for bioprocesses that convert hydrogen gas into one or more biosynthetic products. By maintaining separate hydrogen and oxygen feed gas streams, and forming a recycle gas that introduces a target component of the supply gas to the bioreactor within a target concentration range, the yields, productivities, and safety profiles of the bioprocess can be enhanced.

    METHODS FOR CONTROLLING OXYGEN CONCENTRATION DURING AEROBIC BIOSYNTHESIS
    3.
    发明申请
    METHODS FOR CONTROLLING OXYGEN CONCENTRATION DURING AEROBIC BIOSYNTHESIS 审中-公开

    公开(公告)号：US20190300839A1

    公开(公告)日：2019-10-03

    申请号：US16372099

    申请日：2019-04-01

    申请人： INVISTA NORTH AMERICA S.A.R.L.

    发明人： Gary J. Smith ,  Paul S. Pearlman ,  Gregory S. Kirby

    IPC分类号： C12M1/34

    摘要： The present disclosure provides methods for controlling oxygen concentration during aerobic biosynthesis, e.g., fermentation. The method may comprise feeding an oxygen-containing gas into a vessel including a fermentation feedstock and reacting the fermentation feedstock with the oxygen-containing gas to form a broth including a gaseous phase dispersed within the broth. The gaseous phase may comprise any unreacted oxygen from the oxygen-containing gas. The method further includes reducing the concentration of the unreacted oxygen in the dispersed gaseous phase to less than the limiting oxygen concentration (“LOC”) for flammability before separating the gaseous phase from the fermentation broth. The concentration of the unreacted oxygen in the gaseous phase is reduced by employing oxygen removal schemes or oxygen dilution schemes.