公开(公告)号：US20200085512A1

公开(公告)日：2020-03-19

申请号：US16610355

申请日：2018-05-08

Applicant: IMRIS, Inc.

Inventor： Brendan Reimer ,  Meir Dahan ,  Gord Scarth

IPC: A61B34/20 ,  A61B5/055

Abstract: A region within a body of an imaging subject can be imaged to identify a tumor locus in a three dimensional coordinate system. An opening in the body of the imaging subject can be formed to provide an access location. Using an actuator, a surgical tool can be guided to traverse the access location to access the tumor locus, the surgical tool guided along a specified trajectory in the three dimensional coordinate system by the actuator and configured to resect and remove a first portion of the tumor within the tumor locus.

公开(公告)号：US20140180059A1

公开(公告)日：2014-06-26

申请号：US14072397

申请日：2013-11-05

Applicant: IMRIS INC.

Inventor： Jeff Winter ,  Meir Dahan ,  Labros Petropoulos ,  Brendan Guyot ,  Alexis Denis

IPC: A61N5/10 ,  A61B5/055

CPC classification number: G01R33/3802 ,  A61B5/0555 ,  A61N5/1001 ,  A61N2005/1055 ,  A61N2005/1063 ,  A61N2005/1094 ,  G01R33/288

Abstract: In a method for guiding brachytherapy radiation treatment the patient is supported on a table and an MR magnet is brought into the treatment bunker through doors for imaging while the after-loader for the radiation source delivery is stored away in a storage location outside the RF shield. A safety system controls movement of the after-loader and the magnet. Images of the patient obtained while the patient is on the table are used to locate the applicator with respect to the lesion and organs-at-risk. The MR and X-ray compatible patient support table with MR coil integration includes a removable end-extension, which provides pelvic access for applicator insertion.

Abstract translation: 在用于引导近距离放射治疗放射治疗的方法中，患者被支撑在桌子上，并且MR磁体通过用于成像的门进入处理舱，而用于辐射源输送的后加载器被存储在RF屏蔽外部的存储位置 。 安全系统控制后装载机和磁铁的运动。 使用患者在桌子上获得的患者的图像来定位施用器相对于病变和器官风险。 具有MR线圈集成的MR和X射线兼容的患者支撑台包括可移除的端部延伸部，其提供用于施放器插入的骨盆通路。

公开(公告)号：US20140128724A1

公开(公告)日：2014-05-08

申请号：US13670944

申请日：2012-11-07

Applicant: IMRIS INC.

Inventor： Meir Dahan ,  Mark Alexiuk ,  Wayne Schellekens ,  Vlajko Srzic

IPC: A61B5/055

CPC classification number: A61B5/0555 ,  A61B5/0046 ,  A61B5/6889 ,  A61B5/704 ,  A61G12/004 ,  A61G13/0018 ,  A61G13/02 ,  A61G2210/50 ,  G01R33/3802

Abstract: In MR imaging in a suite of rooms including a diagnostic room and a second surgical room, the magnet includes a diagnostic table separable from a docking station of the magnet and the second room includes a second surgical table. An imaging control computer controls operation of the imaging system and a movement control computer controls operation of the magnet moving system and the patient support table. During imaging in the surgical room, the diagnostic table is separated and docked at a secondary docking station while an emulating computer system cooperate with the imaging control computer system by emulating outputs from the disconnected diagnostic table for controlling operation of the imaging system.

Abstract translation: 在包括诊断室和第二手术室的房间的MR成像中，磁体包括可从磁体的对接站分离的诊断台，第二房间包括第二外科手术台。 成像控制计算机控制成像系统的操作，并且移动控制计算机控制磁体移动系统和患者支撑台的操作。 在手术室成像期间，诊断台被分离并对接在第二对接站，而仿真计算机系统通过仿真来自断开的诊断表的输出来控制成像系统的操作与成像控制计算机系统协作。

公开(公告)号：US20130235969A1

公开(公告)日：2013-09-12

申请号：US13778621

申请日：2013-02-27

Applicant: IMRIS INC.

Inventor： Jeff Winter ,  Michael Westmore ,  Meir Dahan ,  Labros Petropoulos ,  Brendan Guyot ,  David A. Jaffray ,  Marco Carlone ,  Teodor Stanescu

IPC: G01R33/48 ,  G01R33/58 ,  A61B6/00

CPC classification number: G01R33/4812 ,  A61B5/0035 ,  A61B5/0046 ,  A61B5/0555 ,  A61B6/032 ,  A61B6/0457 ,  A61B6/4417 ,  A61B6/5247 ,  A61B6/583 ,  A61B6/584 ,  A61N5/1049 ,  A61N5/1079 ,  A61N2005/1055 ,  A61N2005/1063 ,  G01R33/4808 ,  G01R33/58

Abstract: Apparatus for radiation therapy combines a patient table, an MRI and a radiation treatment apparatus mounted in a common treatment room with the MR magnet movable through a radiation shielded door to an imaging position. An initial MR image and an initial X-ray image is used to generate an RT program for the patient to be carried out in a plurality of separate treatment steps. Before carrying out the procedure, a registration step is performed using a phantom by which X-ray images are registered relative to MR images to generate a transformation algorithm required to align the MR images of the part of the patient relative to the X-ray images. Prior to each separate treatment step a current MR image of the part of the patient is obtained and the transformation algorithm data is used from the current MR image is used in guiding the RT treatment step.

Abstract translation: 用于放射治疗的装置将安装在公共治疗室中的患者台，MRI和放射治疗装置与可通过辐射屏蔽门移动到成像位置的MR磁体组合。 使用初始MR图像和初始X射线图像来生成用于在多个单独的处理步骤中执行的患者的RT程序。 在执行该过程之前，使用相对于MR图像登记X射线图像的体模执行登记步骤，以产生将患者部分的MR图像相对于X射线图像对准所需的变换算法 。 在每个单独的处理步骤之前，获得患者部分的当前MR图像，并且使用来自当前MR图像的变换算法数据来指导RT治疗步骤。

公开(公告)号：US09575148B2

公开(公告)日：2017-02-21

申请号：US14072397

申请日：2013-11-05

Applicant: IMRIS INC.

Inventor： Jeff Winter ,  Meir Dahan ,  Labros Petropoulos ,  Brendan Guyot ,  Alexis Denis

IPC: A61N5/10 ,  A61B5/055 ,  G01R33/38 ,  G01R33/28

CPC classification number: G01R33/3802 ,  A61B5/0555 ,  A61N5/1001 ,  A61N2005/1055 ,  A61N2005/1063 ,  A61N2005/1094 ,  G01R33/288

Abstract: In a method for guiding brachytherapy radiation treatment the patient is supported on a table and an MR magnet is brought into the treatment bunker through doors for imaging while the after-loader for the radiation source delivery is stored away in a storage location outside the RF shield. A safety system controls movement of the after-loader and the magnet. Images of the patient obtained while the patient is on the table are used to locate the applicator with respect to the lesion and organs-at-risk. The MR and X-ray compatible patient support table with MR coil integration includes a removable end-extension, which provides pelvic access for applicator insertion.

Abstract translation: 在用于引导近距离放射治疗放射治疗的方法中，患者被支撑在桌子上，并且MR磁体通过用于成像的门进入处理舱，而用于辐射源输送的后加载器被存储在RF屏蔽外部的存储位置 。 安全系统控制后装载机和磁铁的运动。 使用患者在桌子上获得的患者的图像来定位施用器相对于病变和器官风险。 具有MR线圈集成的MR和X射线兼容的患者支撑台包括可移除的端部延伸部，其提供用于施放器插入的骨盆通路。

公开(公告)号：US09301707B2

公开(公告)日：2016-04-05

申请号：US13670944

申请日：2012-11-07

Applicant: IMRIS INC.

Inventor： Meir Dahan ,  Mark Alexiuk ,  Wayne Schellekens ,  Vlajko Srzic

IPC: A61B5/05 ,  A61B5/055 ,  A61B5/00 ,  G01R33/38 ,  A61G13/02 ,  A61G13/00 ,  A61G12/00

CPC classification number: A61B5/0555 ,  A61B5/0046 ,  A61B5/6889 ,  A61B5/704 ,  A61G12/004 ,  A61G13/0018 ,  A61G13/02 ,  A61G2210/50 ,  G01R33/3802

Abstract: In MR imaging in a suite of rooms including a diagnostic room and a second surgical room, the magnet includes a diagnostic table separable from a docking station of the magnet and the second room includes a second surgical table. An imaging control computer controls operation of the imaging system and a movement control computer controls operation of the magnet moving system and the patient support table. During imaging in the surgical room, the diagnostic table is separated and docked at a secondary docking station while an emulating computer system cooperate with the imaging control computer system by emulating outputs from the disconnected diagnostic table for controlling operation of the imaging system.

Abstract translation: 在包括诊断室和第二手术室的房间的MR成像中，磁体包括可从磁体的对接站分离的诊断台，第二房间包括第二外科手术台。 成像控制计算机控制成像系统的操作，并且移动控制计算机控制磁体移动系统和患者支撑台的操作。 在手术室成像期间，诊断台被分离并对接在第二对接站，而仿真计算机系统通过仿真来自断开的诊断表的输出来控制成像系统的操作与成像控制计算机系统协作。

公开(公告)号：US20160291100A1

公开(公告)日：2016-10-06

申请号：US14677700

申请日：2015-04-02

Applicant: IMRIS, Inc.

Inventor： Seunghoon Ha ,  Haoqin Zhu ,  Labros Petropoulos ,  Meir Dahan

IPC: G01R33/34 ,  G01R33/48 ,  G01R33/28 ,  G01R33/385 ,  G01R33/36

CPC classification number: G01R33/3607 ,  G01R33/34046 ,  G01R33/365 ,  G01R33/3664 ,  G01R33/3678

Abstract: Nuclear magnetic resonance (MR) imaging can include use of an electrical transceiver coil system comprising an array of segmented loops. The array can be arranged about a portion of an imaging subject and arranged to provide surgical access to a region of the imaging subject from at least one direction. The segmented loops can establish a volumetric radio frequency (RF) excitation field across a volume-of-interest associated with the imaging subject in response to the segmented loops receiving specified transmit phases providing a non-90-degree relative phase between segmented coil loops at adjacent ones of the segmented loops. All or at least some of the segmented loops can provide outputs indicative of an RF signal from the imaging subject, the RF signal elicited in response to RF excitation. The transceiver coil system can facilitate pre-operative, intra-operative, or post-operative MR imaging, such as facilitating access for a surgical procedure.

Abstract translation: 核磁共振（MR）成像可以包括使用包括分段环阵列的电收发器线圈系统。 阵列可以围绕成像对象的一部分布置，并且布置成从至少一个方向提供对成像对象的区域的手术进入。 分段环路可以响应于分段环路接收指定的传输相位而在与成像对象相关联的感兴趣体积上建立体积射频（RF）激励场，从而在分段线圈环之间提供非90度相对相位， 相邻的分段循环。 所有或至少一些分段环路可以提供指示来自成像对象的RF信号的输出，RF信号响应于RF激励而引起。 收发器线圈系统可以促进手术前，手术中或术后MR成像，例如促进外科手术的进入。

公开(公告)号：US20150073433A1

公开(公告)日：2015-03-12

申请号：US14306391

申请日：2014-06-17

Applicant: IMRIS INC.

Inventor： Shawn Schaerer ,  Mark Alexiuk ,  Gord Scarth ,  John K. Saunders ,  Meir Dahan

IPC: A61B19/00 ,  A61B5/00 ,  A61B5/055

CPC classification number: A61B5/0064 ,  A61B5/0035 ,  A61B5/0071 ,  A61B5/055 ,  A61B5/7425 ,  A61B34/30 ,  A61B90/37 ,  G01R33/4808

Abstract: In an MR guided surgical system which is carried out in the bore of an MR magnet and uses fluorescence to detect tumor cells, there is provided a microscope system for viewing the required part of a patient which includes stereoscopic viewing components arranged for use in generating 2D and 3D images displayed to the surgeon. The optical assembly is adjustable to change the view and the visual images are overlaid by the MR images. The visual image can be adjusted in response to movement of the surgical tool and the MR image displayed and/or the image obtained can be modified in response to change in the visual image and/or movement of the tool. The components in the bore are made compatible with the MR environment. A fluorescence delivery system is operated to automatically activate the delivery system in response to detection of the level of fluorescence.

Abstract translation: 在MR导引手术系统中，其在MR磁体的孔中进行并使用荧光来检测肿瘤细胞，提供了一种用于观察患者所需部分的显微镜系统，其包括布置用于生成2D的立体观察组件 并向外科医生显示3D图像。 光学组件是可调节的，以改变视野，并且可视图像被MR图像覆盖。 可以响应于手术工具的移动和显示的MR图像来调整视觉图像，和/或可以响应于视觉图像的变化和/或工具的移动来修改获得的图像。 孔中的组件与MR环境兼容。 操作荧光传递系统以响应于荧光水平的检测来自动激活递送系统。