公开(公告)号：US4456139A

公开(公告)日：1984-06-26

申请号：US438605

申请日：1982-11-02

申请人： Henry R. Kent

发明人： Henry R. Kent

IPC分类号： B65D55/06 ,  B65D41/34

CPC分类号： B65D55/066 ,  B65D55/06 ,  Y02W30/807 ,  Y10S428/916

摘要： A tamper-proof closure arrangement for a container includes in one embodiment a seal applied to seal receiving surfaces of the container and closure cap such that the seal is applied internally of the closure cap without removing the closure cap and is irreversibly damaged by any attempt to remove the closure cap, the seal being visible through the closure cap to provide a visual indication of tampering. In an alternative embodiment, the seal is fixed internally of a disposable cap which is mounted on an associated container to overlie a reusable closure cap. The seal is visually observable through the disposable cap and is formed in contacting relation against a three-dimensional surface on the reusable cap such that any attempt at removing the disposable cap irreversibly damages or deforms the seal to provide a visual indication of tampering.

摘要翻译： 用于容器的防篡改封闭装置在一个实施例中包括用于密封容器和封闭盖的接收表面的密封件，使得密封件在封闭盖的内部被施加而不移除封盖，并且由于任何尝试而不可逆地损坏 拆下封盖，密封件可以通过封盖盖可见，以提供篡改的视觉指示。 在替代实施例中，密封件固定在一次性盖的内部，该盖被安装在相关联的容器上以覆盖可重复使用的封闭盖。 密封件通过一次性盖可视地观察并且形成为与可重复使用的盖上的三维表面的接触关系，使得任何去除一次性盖的尝试不可逆地损坏或变形密封件以提供篡改的视觉指示。

公开(公告)号：US5676646A

公开(公告)日：1997-10-14

申请号：US615090

申请日：1996-03-14

申请人： Gunter A. Hofmann ,  Henry R. Kent

发明人： Gunter A. Hofmann ,  Henry R. Kent

IPC分类号： C12N15/09 ,  A61K35/18 ,  A61K48/00 ,  A61M1/36 ,  C12M1/00 ,  C12M1/42 ,  C12M3/00 ,  C12N15/87 ,  A61M37/00

CPC分类号： A61M1/36 ,  A61K35/18 ,  A61K48/00 ,  C12M35/02 ,  C12N15/87

摘要： A flow through apparatus for implanting molecules into living blood cells of a patient, comprises a housing including an elongated flow through chamber having an inlet and an outlet at opposite ends thereof, a pair of elongated spaced apart parallel electrodes disposed between the inlet and the outlet for fluid to flow therebetween, a continuous flow shunt including a pump for withdrawing blood from a patient, passing it through the flow through chamber between the electrodes and returning it to the patient, apparatus for injecting a predetermined quantity of fluid medium carrying preselected molecules into the blood after it has been drawn from the patient and before it passes through said chamber, and an electrical source for applying a predetermined electric signal of a predetermined amplitude and duration to the electrodes for generating and repeatedly applying electric fields of a predetermined amplitude and duration to the flow of the mixture of blood and fluid medium in order to make the walls of preselected cells in the blood transiently permeable to permit molecules to enter the preselected cells without killing the cells.

摘要翻译： 用于将分子注入患者活细胞的流动装置包括壳体，该壳体包括细长的流动通道，其具有在其相对端的入口和出口，一对细长的间隔开的平行电极，设置在入口和出口之间 用于流体在其间流动的连续流动分流器，包括用于从患者抽出血液的泵，使其通过电极之间的流动室并将其返回给患者，用于将预定量的携带预选分子的流体介质注入 从患者抽出血液并通过所述腔室之后的血液，以及用于向电极施加预定振幅和持续时间的预定电信号的电源，用于产生并重复施加预定幅度和持续时间的电场 到血液和流体介质的混合物的流动 使血液中预选细胞的壁瞬时渗透，以使分子进入预选细胞而不会杀死细胞。

公开(公告)号：US5545130A

公开(公告)日：1996-08-13

申请号：US320966

申请日：1994-10-12

申请人： Gunter A. Hofmann ,  Henry R. Kent

发明人： Gunter A. Hofmann ,  Henry R. Kent

IPC分类号： C12N15/09 ,  A61K35/18 ,  A61K48/00 ,  A61M1/36 ,  C12M1/00 ,  C12M1/42 ,  C12M3/00 ,  C12N15/87 ,  A61M35/00

CPC分类号： A61M1/36 ,  A61K35/18 ,  A61K48/00 ,  C12M35/02 ,  C12N15/87

摘要： A flow through apparatus for implanting molecules into living blood cells of a patient, comprises a housing including an elongated flow through chamber having an inlet and an outlet at opposite ends thereof, a pair of elongated spaced apart parallel electrodes disposed between the inlet and the outlet for fluid to flow therebetween, a continuous flow shunt including a pump for withdrawing blood from a patient, passing it through the flow through chamber between the electrodes and returning it to the patient, apparatus for injecting a predetermined quantity of fluid medium carrying preselected molecules into the blood after it has been drawn from the patient and before it passes through said chamber, and an electrical source for applying a predetermined electric signal of a predetermined amplitude and duration to the electrodes for generating and repeatedly applying electric fields of a predetermined amplitude and duration to the flow of the mixture of blood and fluid medium in order to make the walls of preselected cells in the blood transiently permeable to permit molecules to enter the preselected cells without killing the cells.

摘要翻译： 用于将分子注入患者活细胞的流动装置包括壳体，该壳体包括细长的流动通道，其具有在其相对端的入口和出口，一对细长的间隔开的平行电极，设置在入口和出口之间 用于流体在其间流动的连续流动分流器，包括用于从患者抽出血液的泵，使其通过电极之间的流动室并将其返回给患者，用于将预定量的携带预选分子的流体介质注入 从患者抽出血液并通过所述腔室之后的血液，以及用于向电极施加预定振幅和持续时间的预定电信号的电源，用于产生并重复施加预定幅度和持续时间的电场 到血液和流体介质的混合物的流动 使血液中预选细胞的壁瞬时渗透，以使分子进入预选细胞而不会杀死细胞。

公开(公告)号：US4511094A

公开(公告)日：1985-04-16

申请号：US443292

申请日：1982-11-22

申请人： Henry R. Kent

发明人： Henry R. Kent

IPC分类号： B65H81/04 ,  H01F41/02 ,  H01F41/08 ,  H01F41/12

CPC分类号： H01F41/0213

摘要： A winding machine for manufacturing transformer cores includes a ribbon-dispensing assembly which travels in a predetermined path about a stationary mandrel to deposit successive layers of ribbon upon the mandrel under controlled tension while applying transverse pressure to the peripheral surface of the winding to press air from between the layers. In the preferred embodiment, a counterbalanced rotating track engages the ribbon-dispensing assembly as it travels around the mandrel. The ribbon dispensing assembly is preferably transported by a chain drive.

摘要翻译： 用于制造变压器铁芯的绕线机包括：带状分配组件，其在预定的路径中围绕固定的心轴行进，以在受控的张力下将连续的带状层沉积在心轴上，同时向绕组的周边表面施加横向压力以将 层之间。 在优选实施例中，当色带分配组件围绕心轴行进时，平衡旋转轨道与色带分配组件接合。 色带分配组件优选地通过链传动来传送。