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公开(公告)号：US20210147415A1
公开(公告)日：2021-05-20
申请号：US17091247
申请日：2020-11-06
IPC分类号： C07D471/04 , C07D317/60 , C07D235/28 , C07D493/04 , C07D207/337 , C07D209/42 , C07D307/68 , C07C59/70 , C07C59/68 , C07D239/22 , G01N27/447 , G01N33/50
摘要： The invention relates to inhibitors of the NHR2 tetramerization and their use as tumor therapeutics (e.g. against acute myeloid leukemia (AML)), cytostatics, and diagnostic agents.
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公开(公告)号：US20180230143A1
公开(公告)日：2018-08-16
申请号：US15837235
申请日：2017-12-11
IPC分类号： C07D471/04 , C07D209/42 , C07D317/60 , C07D239/22 , C07C59/68 , C07D493/04 , C07D207/337 , C07D307/68 , G01N27/447 , C07C59/70 , G01N33/50 , C07D235/28
CPC分类号： C07D471/04 , C07C59/68 , C07C59/70 , C07D207/337 , C07D209/42 , C07D235/28 , C07D239/22 , C07D307/68 , C07D317/60 , C07D493/04 , G01N27/447 , G01N33/5011 , G01N2333/47
摘要： The invention relates to inhibitors of the NHR2 tetramerization and their use as tumor therapeutics (e.g. against acute myeloid leukemia (AML)), cytostatics, and diagnostic agents.
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3.发明申请公开(公告)号：US20160108031A1
公开(公告)日：2016-04-21
申请号：US14787151
申请日：2014-04-25
IPC分类号： C07D471/04 , C07D307/68 , C07D493/04 , G01N27/447 , C07C59/68 , C07D317/60 , C07D239/22 , G01N33/50 , C07D207/337 , C07D209/42
CPC分类号： C07D471/04 , C07C59/68 , C07C59/70 , C07D207/337 , C07D209/42 , C07D235/28 , C07D239/22 , C07D307/68 , C07D317/60 , C07D493/04 , G01N27/447 , G01N33/5011 , G01N2333/47
摘要： The invention relates to inhibitors of the NHR2 tetramerization and their use as tumor therapeutics (e.g. against acute myeloid leukemia (AML)), cytostatics, and diagnostic agents.
摘要翻译： 本发明涉及NHR2四聚化的抑制剂及其作为肿瘤治疗剂（例如针对急性骨髓性白血病（AML）），细胞抑制剂和诊断剂的用途。
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