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公开(公告)号：US12226222B2
公开(公告)日：2025-02-18
申请号：US18464441
申请日：2023-09-11
Applicant: Hologic, Inc.
Inventor： Estefania Alvarez
IPC: A61B5/00 , A61B5/1468 , G16H20/10 , G16H50/20
Abstract: Examples of the present disclosure describe systems and methods for the long-term, real-time active monitoring of a wireless implant. In aspects, a wireless biosensor may be implanted in a breast biopsy cavity. The biosensor may detect biochemical parameter data of the breast biopsy cavity and the human body. The biosensor may transmit the detected biochemical parameter data in real-time to a surveillance system wirelessly coupled to the biosensor. The surveillance system may then facilitate the evaluation of the biochemical parameter data. In examples, the evaluation may comprise detecting trends in a tumor's microenvironment, monitoring the progress of a treatment, or adjusting a treatment to tailor a personalized treatment.
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公开(公告)号：US11937886B2
公开(公告)日：2024-03-26
申请号：US17524297
申请日：2021-11-11
Applicant: HOLOGIC, INC.
Inventor： John Laviola , Shawn St. Pierre , Brian Stellmach , Lori Fontaine , Joseph A. Stand, III , Estefania Alvarez , Stephen Grantz , Michelle Dawn Lyman , Shannon Marie Butler , Yuliya Mathis
IPC: A61B34/20 , A61B5/06 , A61B8/00 , A61B8/08 , A61B17/3211 , A61B34/00 , A61B90/00 , G06T7/70 , A61B5/00 , A61B5/145 , A61B17/00 , A61B18/00
CPC classification number: A61B34/20 , A61B5/065 , A61B8/0841 , A61B8/085 , A61B8/4254 , A61B8/46 , A61B8/463 , A61B8/481 , A61B17/3211 , A61B90/39 , G06T7/70 , A61B5/14503 , A61B5/4842 , A61B8/0825 , A61B2017/00867 , A61B2017/00964 , A61B2018/00595 , A61B2034/2063 , A61B2034/2065 , A61B34/25 , A61B2090/378 , A61B2090/3904 , A61B2090/3908 , A61B2090/3912 , A61B2090/3925 , A61B2090/395 , A61B2090/3995 , G06T2207/10132 , G06T2207/20081 , G06T2207/30096 , G06T2207/30204
Abstract: Disclosed biopsy markers are adapted to serve as localization markers during a surgical procedure. Adaptation includes incorporation of materials detectable under ultrasound during surgery, as well as features for co-registration with image guidance or other real-time imaging technologies during surgery. Such biopsy markers, when used as localization markers, improve patient comfort and reduce challenges in surgical coordination and surgery time. Additional disclosed biopsy markers are adapted to serve as monitoring and/or detection apparatuses, Localization of an implanted marker may be done with ultrasound technology. Ultrasound image data is analyzed to identify the implanted marker. A distance to the marker or a lesion may be determined and displayed. The determined distance may be a distance between the ultrasound probe and the marker or lesion, a distance between the marker or lesion and an incision instrument, and/or a distance between the ultrasound probe and the incision instrument.
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公开(公告)号：US12133695B2
公开(公告)日：2024-11-05
申请号：US17524590
申请日：2021-11-11
Applicant: HOLOGIC, INC.
Inventor： John Laviola , Shawn St. Pierre , Brian Stellmach , Lori Fontaine , Joseph A. Stand, III , Estefania Alvarez , Stephen Grantz , Michelle Dawn Lyman , Shannon Marie Butler , Yuliya Mathis
IPC: A61B34/20 , A61B5/06 , A61B8/00 , A61B8/08 , A61B17/3211 , A61B90/00 , G06T7/70 , A61B5/00 , A61B5/145 , A61B17/00 , A61B18/00 , A61B34/00
Abstract: Disclosed biopsy markers are adapted to serve as localization markers during a surgical procedure. Adaptation includes incorporation of materials detectable under ultrasound during surgery, as well as features for co-registration with image guidance or other real-time imaging technologies during surgery. Such biopsy markers, when used as localization markers, improve patient comfort and reduce challenges in surgical coordination and surgery time. Additional disclosed biopsy markers are adapted to serve as monitoring and/or detection apparatuses. Localization of an implanted marker may be done with ultrasound technology. Ultrasound image data is analyzed to identify the implanted marker. A distance to the marker or a lesion may be determined and displayed. The determined distance may be a distance between the ultrasound probe and the marker or lesion, a distance between the marker or lesion and an incision instrument, and/or a distance between the ultrasound probe and the incision instrument.
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公开(公告)号：US11890299B2
公开(公告)日：2024-02-06
申请号：US16888499
申请日：2020-05-29
Applicant: HOLOGIC, INC.
Inventor： Victor Manuel Solano Umaña , Estefania Alvarez
CPC classification number: A61K33/242 , A61K9/0034 , A61K9/14 , A61M31/00 , A61P41/00 , A61B2018/0063 , A61B2018/00559 , A61B2018/00577 , A61B2218/007 , A61M2210/1433
Abstract: A method of ablating a target body tissue, such as uterine endometrial lining tissue, includes applying an agent comprising HAuCl4 to the target body tissue, wherein the HAuCl4 has a molecular size greater than 50 microns, and removing the agent comprising HAuCl4 from the target tissue after ablation of the target tissue begins.
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公开(公告)号：US12263048B2
公开(公告)日：2025-04-01
申请号：US18528055
申请日：2023-12-04
Applicant: HOLOGIC, INC
Inventor： Estefania Alvarez , Adam Kozak , Jaimee Robertson , Stephen Spiegelberg
Abstract: A biopsy site marker configured to expand upon deployment into a biopsy cavity, and visible under several different imaging modalities, comprises a superabsorbent hydrogel component and a radiopaque element. The hydrogel is in a compressed, dehydrated state prior to deployment to facilitate placement of the marker within the biopsy site, and thereafter expands upon deployment in the biopsy site. Such expansion limits migration of the site marker.
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Patent Agency Ranking
公开(公告)号：US11464585B2
公开(公告)日：2022-10-11
申请号：US17510274
申请日：2021-10-25
Applicant: HOLOGIC, INC.
Inventor： John Laviola , Shawn St. Pierre , Brian Stellmach , Lori Fontaine , Joseph A. Stand, III , Estefania Alvarez , Stephen Grantz , Michelle Dawn Lyman , Shannon Marie Butler , Yuliya Mathis
IPC: A61B34/20 , A61B90/00 , A61B8/08 , A61B8/00 , A61B34/00 , G06T7/70 , A61B5/06 , A61B17/3211 , A61B5/145 , A61B5/00 , A61B17/00 , A61B18/00
Abstract: Disclosed biopsy markers are adapted to serve as localization markers during a surgical procedure. Adaptation includes incorporation of materials detectable under ultrasound during surgery, as well as features for co-registration with image guidance or other real-time imaging technologies during surgery. Such biopsy markers, when used as localization markers, improve patient comfort and reduce challenges in surgical coordination and surgery time. Additional disclosed biopsy markers are adapted to serve as monitoring and/or detection apparatuses. Localization of an implanted marker may be done with ultrasound technology. Ultrasound image data is analyzed to identify the implanted marker. A distance to the marker or a lesion may be determined and displayed. The determined distance may be a distance between the ultrasound probe and the marker or lesion, a distance between the marker or lesion and an incision instrument, and/or a distance between the ultrasound probe and the incision instrument.
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公开(公告)号：US11234772B2
公开(公告)日：2022-02-01
申请号：US16771379
申请日：2018-12-11
Applicant: HOLOGIC, INC.
Inventor： John Laviola , Shawn St. Pierre , Brian Stellmach , Lori Fontaine , Joseph A. Stand, III , Estefania Alvarez , Stephen Grantz , Michelle Dawn Lyman , Shannon Marie Butler , Yuliya Mathis
Abstract: Disclosed biopsy markers are adapted to serve as localization markers during a surgical procedure. Adaptation includes incorporation of materials detectable under ultrasound during surgery, as well as features for co-registration with image guidance or other real-time imaging technologies during surgery. Such biopsy markers, when used as localization markers, improve patient comfort and reduce challenges in surgical coordination and surgery time. Additional disclosed biopsy markers are adapted to serve as monitoring and/or detection apparatuses. Localization of an implanted marker may be done with ultrasound technology. Ultrasound image data is analyzed to identify the implanted marker. A distance to the marker or a lesion may be determined and displayed. The determined distance may be a distance between the ultrasound probe and the marker or lesion, a distance between the marker or lesion and an incision instrument, and/or a distance between the ultrasound probe and the incision instrument.
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公开(公告)号：US12133696B2
公开(公告)日：2024-11-05
申请号：US17524941
申请日：2021-11-12
Applicant: HOLOGIC, INC.
Inventor： John Laviola , Shawn St. Pierre , Brian Stellmach , Lori Fontaine , Joseph A. Stand, III , Estefania Alvarez , Stephen Grantz , Michelle Dawn Lyman , Shannon Marie Butler , Yuliya Mathis
IPC: A61B34/20 , A61B5/06 , A61B8/00 , A61B8/08 , A61B17/3211 , A61B90/00 , G06T7/70 , A61B5/00 , A61B5/145 , A61B17/00 , A61B18/00 , A61B34/00
Abstract: Disclosed biopsy markers are adapted to serve as localization markers during a surgical procedure. Adaptation includes incorporation of materials detectable under ultrasound during surgery, as well as features for co-registration with image guidance or other real-time imaging technologies during surgery. Such biopsy markers, when used as localization markers, improve patient comfort and reduce challenges in surgical coordination and surgery time. Additional disclosed biopsy markers are adapted to serve as monitoring and/or detection apparatuses. Localization of an implanted marker may be done with ultrasound technology. Ultrasound image data is analyzed to identify the implanted marker. A distance to the marker or a lesion may be determined and displayed. The determined distance may be a distance between the ultrasound probe and the marker or lesion, a distance between the marker or lesion and an incision instrument, and/or a distance between the ultrasound probe and the incision instrument.
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公开(公告)号：US12029503B2
公开(公告)日：2024-07-09
申请号：US17557773
申请日：2021-12-21
Applicant: HOLOGIC, INC.
Inventor： John Laviola , Shawn St. Pierre , Brian Stellmach , Lori Fontaine , Joseph A. Stand, III , Estefania Alvarez , Stephen Grantz , Michelle Dawn Lyman , Shannon Marie Butler , Yuliya Mathis
IPC: A61B34/20 , A61B5/06 , A61B8/00 , A61B8/08 , A61B17/3211 , A61B90/00 , G06T7/70 , A61B5/00 , A61B5/145 , A61B17/00 , A61B18/00 , A61B34/00
CPC classification number: A61B34/20 , A61B5/065 , A61B8/0841 , A61B8/085 , A61B8/4254 , A61B8/46 , A61B8/463 , A61B8/481 , A61B17/3211 , A61B90/39 , G06T7/70 , A61B5/14503 , A61B5/4842 , A61B8/0825 , A61B2017/00867 , A61B2017/00964 , A61B2018/00595 , A61B2034/2063 , A61B2034/2065 , A61B34/25 , A61B2090/378 , A61B2090/3904 , A61B2090/3908 , A61B2090/3912 , A61B2090/3925 , A61B2090/395 , A61B2090/3995 , G06T2207/10132 , G06T2207/20081 , G06T2207/30096 , G06T2207/30204
Abstract: Disclosed biopsy markers are adapted to serve as localization markers during a surgical procedure. Adaptation includes incorporation of materials detectable under ultrasound during surgery, as well as features for co-registration with image guidance or other real-time imaging technologies during surgery. Such biopsy markers, when used as localization markers, improve patient comfort and reduce challenges in surgical coordination and surgery time. Additional disclosed biopsy markers are adapted to serve as monitoring and/or detection apparatuses. Localization of an implanted marker may be done with ultrasound technology. Ultrasound image data is analyzed to identify the implanted marker. A distance to the marker or a lesion may be determined and displayed. The determined distance may be a distance between the ultrasound probe and the marker or lesion, a distance between the marker or lesion and an incision instrument, and/or a distance between the ultrasound probe and the incision instrument.
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公开(公告)号：US11877898B2
公开(公告)日：2024-01-23
申请号：US16463023
申请日：2017-09-27
Applicant: HOLOGIC, INC
Inventor： Estefania Alvarez , Adam Kozak , Jaimee Robertson , Stephen Spiegelberg
CPC classification number: A61B90/39 , A61B10/0041 , A61B2017/00796 , A61B2017/00845 , A61B2017/00853 , A61B2017/00867 , A61B2017/00898 , A61B2090/3904 , A61B2090/3908 , A61B2090/3925 , A61B2090/3954 , A61B2090/3966 , A61B2090/3987 , A61B2090/3995
Abstract: A biopsy site marker configured to expand upon deployment into a biopsy cavity, and visible under several different imaging modalities, comprises a superabsorbent hydrogel component and a radiopaque element. The hydrogel is in a compressed, dehydrated state prior to deployment to facilitate placement of the marker within the biopsy site, and thereafter expands upon deployment in the biopsy site. Such expansion limits migration of the site marker.
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