公开(公告)号：US12174143B2

公开(公告)日：2024-12-24

申请号：US17272698

申请日：2018-10-29

Applicant: HITACHI HIGH-TECH CORPORATION

Inventor： Jin Matsumura ,  Ayaka Okuno ,  Ryusuke Kimura ,  Takashi Anazawa ,  Michiru Fujioka ,  Wataru Sato ,  Taro Nakazawa ,  Motohiro Yamazaki

IPC: G01N27/447

Abstract: Provided is an electrophoresis device for enhancing its analysis performance. In order to achieve the task, the electrophoresis device includes a capillary array constituted by a capillary, a capillary head for bundling an end of the capillary, an electrode holder for holding an electrode provided at the other end of the capillary and a detector provided for the capillary, a first heater for heating the capillary, and an irradiation detection unit for irradiating a light to the detector to detect a fluorescence generated from a fluorescence labelled sample in the capillary. The electrophoresis device further includes a second heater for heating the detector.

公开(公告)号：US11644438B2

公开(公告)日：2023-05-09

申请号：US17168390

申请日：2021-02-05

Applicant: Hitachi High-Tech Corporation

Inventor： Ayaka Okuno ,  Motohiro Yamazaki ,  Taro Nakazawa ,  Mitsuhiro Miyazaki ,  Ryusuke Kimura

IPC: G01N27/447

CPC classification number: G01N27/44708 ,  G01N27/44704

Abstract: A capillary cartridge achieves both improvement of attachability and improvement of heat dissipation performance for realizing short-time analysis. A heat dissipation body is provided between a capillary having a detection unit provided in a part thereof and a plate-like support body that supports the capillary, and temperature increase inside the capillary is suppressed by the heat dissipation body, and thereby, electrophoresis can be performed under a high voltage application condition where the amount of heat increases and analysis time is reduced. In addition, it is possible to redress complexity of an operation by reducing a fixing place at the time of attachment to only a detection unit and an electrode holder by using an integration structure in which the capillary, the supporting body, and the heat radiating body are integrated.

公开(公告)号：US12196707B2

公开(公告)日：2025-01-14

申请号：US17533317

申请日：2021-11-23

Applicant: Hitachi High-Tech Corporation

Inventor： Ryusuke Kimura ,  Motohiro Yamazaki ,  Hitoshi Miyata ,  Hiroyuki Higashino

IPC: G01N27/447

Abstract: Provided is an electrophoresis device that, by electrophoresis, feeds a sample into capillaries and optically detects the sample, the electrophoresis device being provided with capillaries, a capillary head provided at the distal end of the capillaries, a phoretic medium-filled container used for electrophoresis and filled with a phoretic medium, a guide member that covers the side surface of the phoretic medium-filled container, a seal member that seals from below the phoretic medium filled in the phoretic medium-filled container, and a plunger that presses the seal member.

公开(公告)号：US11226307B2

公开(公告)日：2022-01-18

申请号：US16885828

申请日：2020-05-28

Applicant: Hitachi High-Tech Corporation

Inventor： Ryusuke Kimura ,  Motohiro Yamazaki ,  Hitoshi Miyata ,  Hiroyuki Higashino

IPC: G01N27/447

Abstract: Provided is an electrophoresis device that, by electrophoresis, feeds a sample into capillaries and optically detects the sample, the electrophoresis device being provided with capillaries, a capillary head provided at the distal end of the capillaries, a phoretic medium-filled container used for electrophoresis and filled with a phoretic medium, a guide member that covers the side surface of the phoretic medium-filled container, a seal member that seals from below the phoretic medium filled in the phoretic medium-filled container, and a plunger that presses the seal member.

公开(公告)号：US20230046895A1

公开(公告)日：2023-02-16

申请号：US17797588

申请日：2020-03-06

Applicant: HITACHI HIGH-TECH CORPORATION

Inventor： Ryusuke Kimura ,  Motohiro Yamazaki

IPC: G01N27/447

Abstract: Provided is the technique for efficiently using the phoresis medium contained in the phoresis medium container by minimizing the remaining phoresis medium as small as possible, and further lowering the running cost. The disclosure proposes the measurement system as an example, which includes an electrophoresis device and a computer. The electrophoresis device includes a phoresis medium container for storing a phoresis medium, a capillary having its inside filled with the phoresis medium, a delivery mechanism for delivering the phoresis medium in the phoresis medium container to the capillary, and a device control section for controlling an operation of the delivery mechanism. The computer calculates a deliverable number of times from an amount of the phoresis medium in the phoresis medium container and an estimated delivery amount of the phoresis medium delivered by the delivery mechanism (see FIG 16).

公开(公告)号：US10942147B2

公开(公告)日：2021-03-09

申请号：US15739184

申请日：2015-07-01

Applicant: Hitachi High-Tech Corporation

Inventor： Ayaka Okuno ,  Motohiro Yamazaki ,  Taro Nakazawa ,  Mitsuhiro Miyazaki ,  Ryusuke Kimura

IPC: G01N27/447

Abstract: A capillary cartridge achieves both improvement of attachability and improvement of heat dissipation performance for realizing short-time analysis. A heat dissipation body is provided between a capillary having a detection unit provided in a part thereof and a plate-like support body that supports the capillary, and temperature increase inside the capillary is suppressed by the heat dissipation body, and thereby, electrophoresis can be performed under a high voltage application condition where the amount of heat increases and analysis time is reduced. In addition, it is possible to redress complexity of an operation by reducing a fixing place at the time of attachment to only a detection unit and an electrode holder by using an integration structure in which the capillary, the supporting body, and the heat radiating body are integrated.