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公开(公告)号：US11717229B2
公开(公告)日：2023-08-08
申请号：US17109475
申请日：2020-12-02
申请人： HI LLC
发明人： Alejandro Ojeda , Husam Katnani
CPC分类号： A61B5/7214 , A61B5/0075 , A61B5/0082 , A61B5/024 , A61B5/725
摘要： A physiological activity detection system comprises a signal acquisition module configured for non-invasively acquiring a signal from an anatomical structure of a user, the acquired signal having a physiological-encoded component and a periodic artifact component that dominates the physiological-encoded component. The physiological activity detection system further comprises a phase-locked loop (PLL) component configured for estimating a phase of the periodic artifact component of the acquired signal, and generating a periodic reference signal having a phase representative of the estimated phase of the periodic artifact component of the acquired signal.
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公开(公告)号：US20210290170A1
公开(公告)日：2021-09-23
申请号：US17202631
申请日：2021-03-16
申请人： HI LLC
发明人： Katherine Perdue , Ryan Field , Husam Katnani , Jennifer Rines , Alejandro Ojeda
IPC分类号： A61B5/00
摘要： An illustrative system includes a wearable assembly configured to be worn by a user and comprising a first detector configured to detect a first set of photon arrival times and output a first signal representative of the first set of photon arrival times, and a second detector configured to detect a second set of photon arrival times and output a second signal representative of the second set of photon arrival times. The system further includes a processing unit configured to identify a first intensity change in the first signal, identify a second intensity change in the second signal, determine that the first and second intensity changes are time correlated, and determine, based on the determining that the first and second intensity changes are time correlated, that the first and second intensity changes are representative of a motion artifact caused by movement of the user.
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3.发明申请公开(公告)号：US20210265025A1
公开(公告)日：2021-08-26
申请号：US17176321
申请日：2021-02-16
申请人： HI LLC
发明人： Husam Katnani , Antonio H. Lara , Alejandro Ojeda , Julien Dubois , Viktoria Rojkova , Bryan Johnson , Gabriel Lerner
摘要： An illustrative research support computing system maintains subject data representative of attributes for research subjects included in a potential subject pool for potential research studies. The system receives, from a client device, an input dataset representative of: 1) a set of parameters defining a research study to be conducted with respect to a research subject group, and 2) a set of criteria for research subjects that are to be included in the research subject group. The system designates a research subject included in the potential subject pool for inclusion in the research subject group based on the set of criteria, and receives research data detected for the research subject in accordance with the set of parameters. The system also provides an output dataset generated based on the research data detected for the research subject in accordance with the set of parameters. Corresponding methods and systems are also disclosed.
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公开(公告)号：US20210290171A1
公开(公告)日：2021-09-23
申请号：US17202681
申请日：2021-03-16
申请人： HI LLC
发明人： Husam Katnani , Alejandro Ojeda , Katherine Perdue
IPC分类号： A61B5/00
摘要： An illustrative optical measurement system includes a light source configured to emit light directed at a target within a user, the target covered by a superficial layer, and an array of photodetectors configured to detect photons of the light after the light is scattered. The system further includes a processor configured to record, during a first and a second time period, a first and a second set of timestamp symbols, respectively, based on a first and a second subset of the array of photodetectors detecting a first subset of the photons that are scattered by the superficial layer and a second subset of the photons that are scattered by the target and the superficial layer, respectively. The processor is further configured to filter, based on the first set of histogram data, the second set of histogram data, and determine, based on the filtering, histogram data corresponding to the target.
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公开(公告)号：US20210259614A1
公开(公告)日：2021-08-26
申请号：US17176309
申请日：2021-02-16
申请人： HI LLC
发明人： Alejandro Ojeda , Ryan Field , Husam Katnani , Bruno Do Valle , Isai Olvera
摘要： An illustrative multimodal measurement system includes a wearable assembly configured to be worn by a user and comprising a plurality of light sources each configured to emit light directed at a target within the user, a plurality of detectors configured to detect arrival times for photons of the light after the light is scattered by the target, and a plurality of electrodes configured to be external to the user and detect electrical activity of the target.
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公开(公告)号：US20210169424A1
公开(公告)日：2021-06-10
申请号：US17109475
申请日：2020-12-02
申请人： HI LLC
发明人： Alejandro Ojeda , Husam Katnani
摘要： A physiological activity detection system comprises a signal acquisition module configured for non-invasively acquiring a signal from an anatomical structure of a user, the acquired signal having a physiological-encoded component and a periodic artifact component that dominates the physiological-encoded component. The physiological activity detection system further comprises a phase-locked loop (PLL) component configured for estimating a phase of the periodic artifact component of the acquired signal, and generating a periodic reference signal having a phase representative of the estimated phase of the periodic artifact component of the acquired signal.
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公开(公告)号：US20240090816A1
公开(公告)日：2024-03-21
申请号：US18521771
申请日：2023-11-28
申请人： HI LLC
发明人： Alejandro Ojeda , Ryan Field , Husam Katnani , Bruno Do Valle , Isai Olvera
CPC分类号： A61B5/369 , A61B5/0075 , A61B5/291 , A61B5/6803
摘要： An illustrative multimodal measurement system includes a wearable assembly configured to be worn by a user; and a module configured to be removably inserted into the wearable assembly and comprising: a housing, a printed circuit board (PCB) and a light guide assembly configured to emit light directed at a target within the user. The light guide assembly comprises: a lower light guide portion housed within the housing and having a proximal end attached to the PCB, a conductive spring member housed within the housing and comprising a coil positioned around an external surface of the lower light guide portion, and a conductive upper light guide portion connected to the lower light guide portion and configured to protrude from an upper surface of the housing and be in contact with a surface of a body of the user.
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公开(公告)号：US11883181B2
公开(公告)日：2024-01-30
申请号：US17176309
申请日：2021-02-16
申请人： HI LLC
发明人： Alejandro Ojeda , Ryan Field , Husam Katnani , Bruno Do Valle , Isai Olvera
CPC分类号： A61B5/369 , A61B5/0075 , A61B5/291 , A61B5/6803
摘要： An illustrative multimodal measurement system includes a wearable assembly configured to be worn by a user and comprising a plurality of light sources each configured to emit light directed at a target within the user, a plurality of detectors configured to detect arrival times for photons of the light after the light is scattered by the target, and a plurality of electrodes configured to be external to the user and detect electrical activity of the target.
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9.发明授权公开(公告)号：US11515014B2
公开(公告)日：2022-11-29
申请号：US17176321
申请日：2021-02-16
申请人： HI LLC
发明人： Husam Katnani , Antonio H. Lara , Alejandro Ojeda , Julien Dubois , Viktoria Rojkova , Bryan Johnson , Gabriel Lerner
摘要： An illustrative research support computing system maintains subject data representative of attributes for research subjects included in a potential subject pool for potential research studies. The system receives, from a client device, an input dataset representative of: 1) a set of parameters defining a research study to be conducted with respect to a research subject group, and 2) a set of criteria for research subjects that are to be included in the research subject group. The system designates a research subject included in the potential subject pool for inclusion in the research subject group based on the set of criteria, and receives research data detected for the research subject in accordance with the set of parameters. The system also provides an output dataset generated based on the research data detected for the research subject in accordance with the set of parameters. Corresponding methods and systems are also disclosed.
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