Systems and methods for noise removal in an optical measurement system

    公开(公告)号:US12059270B2

    公开(公告)日:2024-08-13

    申请号:US17233033

    申请日:2021-04-16

    申请人: HI LLC

    IPC分类号: A61B5/00 G16H40/67

    摘要: An illustrative optical measurement system includes a light source configured to emit light directed at a target within a user. The system further includes a detector configured to detect photon arrival times for photons of the light after the light is scattered by the target. The system further includes a processor configured to determine, based on the photon arrival times, histogram data associated with the target, the histogram data including noise. The processor is further configured to determine, based on the photon arrival times, a random matrix corresponding to the photon arrival times. The processor is further configured to determine, based on the random matrix, a noise distribution representing a distribution of the noise within the histogram data. The processor is further configured to generate clean histogram data using the noise distribution to filter at least a portion of the noise from the histogram data.

    ESTIMATION OF SOURCE-DETECTOR SEPARATION IN AN OPTICAL MEASUREMENT SYSTEM

    公开(公告)号:US20240197185A1

    公开(公告)日:2024-06-20

    申请号:US18588846

    申请日:2024-02-27

    申请人: HI LLC

    IPC分类号: A61B5/00 G01B11/14

    摘要: An optical measurement system includes a light source configured to emit a first light pulse and a second light pulse toward a target, a detector, and a processing unit. The first light pulse has a first wavelength and the second light pulse has a second wavelength different from the first wavelength. The processing unit is configured to determine a plurality of temporal distributions of photons included in the first light pulse and the second light pulse and detected by the detector after the photons are scattered by the target, and determine, based on the plurality of temporal distributions and a source-detector distance estimation model, a distance between the light source and the detector.

    Non-invasive optical detection system and method

    公开(公告)号:US11857316B2

    公开(公告)日:2024-01-02

    申请号:US16382461

    申请日:2019-04-12

    申请人: HI LLC

    IPC分类号: A61B5/1455 A61B5/00

    摘要: In a non-invasive optical detection system and method, sample light is delivered into a scattering medium. A first portion of the sample light passing through a volume of interest exits the scattering medium as signal light, and a second portion of the sample light passing through a volume of non-interest exits the scattering medium as background light that is combined with the signal light to create a sample light pattern. Reference light is combined with the sample light pattern to create an interference light pattern having a holographic beat component. Ultrasound is emitted into the volume of non-interest in a manner that decorrelates the background light of the sample light pattern from the holographic beat component. The holographic beat component is detected during the measurement period. An optical parameter of the volume of interest is determined based on the detected holographic beat component.

    Real-time periodic artifact extraction from a physiological signal

    公开(公告)号:US11717229B2

    公开(公告)日:2023-08-08

    申请号:US17109475

    申请日:2020-12-02

    申请人: HI LLC

    IPC分类号: A61B5/00 A61B5/024

    摘要: A physiological activity detection system comprises a signal acquisition module configured for non-invasively acquiring a signal from an anatomical structure of a user, the acquired signal having a physiological-encoded component and a periodic artifact component that dominates the physiological-encoded component. The physiological activity detection system further comprises a phase-locked loop (PLL) component configured for estimating a phase of the periodic artifact component of the acquired signal, and generating a periodic reference signal having a phase representative of the estimated phase of the periodic artifact component of the acquired signal.