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公开(公告)号：US10800836B2
公开(公告)日：2020-10-13
申请号：US15207859
申请日：2016-07-12
Applicant: H. Lundbeck A/S
Inventor： Pekka Kallunki , Karina Fog , Louise Buur Vesterager , Ann-Louise Bergstrôm , Florence Sotty , David Satijn , Edward van den Brink , Paul Parren , Rik Rademaker , Tom Vink , Ibrahim John Malik , Liliana Christina Pereira Montezinho
Abstract: The invention relates to novel monoclonal anti-alpha-synuclein antibodies. The antibodies can be used for treating a synucleinopathy such as Parkinson's disease (including idiopathic and inherited forms of Parkinson's disease), Diffuse Lewy Body Disease (DLBD), Lewy body variant of Alzheimer's disease (LBV), Combined Alzheimer's and Parkinson disease, pure autonomic failure and multiple system atrophy.
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公开(公告)号：US10479835B2
公开(公告)日：2019-11-19
申请号：US15743549
申请日：2016-07-12
Applicant: H. Lundbeck A/S
Inventor： Lars Christian Biilmann Rønn , Ibrahim John Malik , Jeffrey B. Stavenhagen , Søren Christensen , Jan Egebjerg , Arnout Gerritsen , Edward Van Den Brink , Paul Parren , Rob De Jong
Abstract: The present invention relates to monoclonal anti-Sortilin antibodies which have been found useful in correcting a deficient level of progranulin (PGRN). In particular, these antibodies can be used in the treatment of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS).
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公开(公告)号：US20180305455A1
公开(公告)日：2018-10-25
申请号：US15743549
申请日：2016-07-12
Applicant: H. Lundbeck A/S
Inventor： Lars Christian Biilmann Rønn , Ibrahim John Malik , Jeffrey b. Stavenhagen , Søren Christensen , Jan Egebjerg , Arnout Gerritsen , Edward Van Den Brink , Paul Parren , Rob De Jong
IPC: C07K16/28 , A61K39/395 , A61P25/28
Abstract: The present invention relates to monoclonal anti-Sortilin antibodies which have been found useful in correcting a deficient level of progranulin (PGRN). In particular, these antibodies can be used in the treatment of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS).
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公开(公告)号：US20180179270A1
公开(公告)日：2018-06-28
申请号：US15812363
申请日：2017-11-14
Applicant: H. Lundbeck A/S
Inventor： Pekka Kallunki , Karina Fog , Louise Buur Vesterager , Ann-Louise Bergstrôm , Florence Sotty , David Satijn , Edward van den Brink , Paul Parren , Rik Rademaker , Tom Vink , Ibrahim John Malik , Liliana Christina Pereira Montezinho
CPC classification number: C07K16/18 , A61K39/3955 , A61K51/00 , A61K2039/505 , C07K2317/21 , C07K2317/33 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , G01N33/6896 , G01N2800/2835
Abstract: The invention relates to novel monoclonal anti-alpha-synuclein antibodies. The antibodies can be used for treating a synucleinopathy such as Parkinson's disease (including idiopathic and inherited forms of Parkinson's disease), Diffuse Lewy Body Disease (DLBD), Lewy body variant of Alzheimer's disease (LBV), Combined Alzheimer's and Parkinson disease, pure autonomic failure and multiple system atrophy.
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公开(公告)号：US11542323B2
公开(公告)日：2023-01-03
申请号：US17088307
申请日：2020-11-03
Applicant: H. Lundbeck A/S
Inventor： Pekka Kallunki , Karina Fog , Louise Buur Vesterager , Ann-Louise Bergstrôm , Florence Sotty , David Satijn , Edward Van Den Brink , Paul Parren , Rik Rademaker , Tom Vink , Ibrahim John Malik , Liliana Christina Pereira Montezinho , Jeffrey B Stavenhagen
Abstract: The invention relates to novel monoclonal anti-alpha-synuclein antibodies. The antibodies can be used for treating a synucleinopathy such as Parkinson's disease (including idiopathic and inherited forms of Parkinson's disease), Diffuse Lewy Body Disease (DLBD), Lewy body variant of Alzheimer's disease (LBV), Combined Alzheimer's and Parkinson disease, pure autonomic failure and multiple system atrophy.
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Patent Agency Ranking
公开(公告)号：US10647764B2
公开(公告)日：2020-05-12
申请号：US16443225
申请日：2019-06-17
Applicant: H. Lundbeck A/S
Inventor： Pekka Kallunki , Karina Fog , Louise Buur Vesterager , Ann-Louise Bergstrôm , Florence Sotty , David Satijn , Edward Van Den Brink , Paul Parren , Rik Rademaker , Tom Vink , Ibrahim John Malik , Liliana Christina Pereira Montezinho
Abstract: The invention relates to novel monoclonal anti-alpha-synuclein antibodies. The antibodies can be used for treating a synucleinopathy such as Parkinson's disease (including idiopathic and inherited forms of Parkinson's disease), Diffuse Lewy Body Disease (DLBD), Lewy body variant of Alzheimer's disease (LBV), Combined Alzheimer's and Parkinson disease, pure autonomic failure and multiple system atrophy.
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公开(公告)号：US10428147B2
公开(公告)日：2019-10-01
申请号：US15207880
申请日：2016-07-12
Applicant: H. Lundbeck A/S
Inventor： Lars Christian Biilmann Rønn , Ibrahim John Malik , Søren Christensen , Jan Egebjerg , Jeffrey B. Stavenhagen , Arnout Gerritsen , Edward van den Brink , Paul Parren , Rob de Jong
IPC: C07K16/28 , A61K39/395 , A61K39/00 , A61P25/28
Abstract: The present invention relates to monoclonal anti-Sortilin antibodies which have been found useful in correcting a deficient level of progranulin (PGRN). In particular, these antibodies can be used in the treatment of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS).
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公开(公告)号：US10358484B2
公开(公告)日：2019-07-23
申请号：US15812410
申请日：2017-11-14
Applicant: H. Lundbeck A/S
Inventor： Pekka Kallunki , Karina Fog , Louise Buur Vesterager , Ann-Louise Bergstrôm , Florence Sotty , David Satijn , Edward van den Brink , Paul Parren , Rik Rademaker , Tom Vink , Ibrahim John Malik , Liliana Christina Pereira Montezinho
IPC: C07K16/18 , A61K39/395 , A61K51/00 , G01N33/68 , A61K39/00
Abstract: The invention relates to novel monoclonal anti-alpha-synuclein antibodies. The antibodies can be used for treating a synucleinopathy such as Parkinson's disease (including idiopathic and inherited forms of Parkinson's disease), Diffuse Lewy Body Disease (DLBD), Lewy body variant of Alzheimer's disease (LBV), Combined Alzheimer's and Parkinson disease, pure autonomic failure and multiple system atrophy.
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公开(公告)号：US20180179271A1
公开(公告)日：2018-06-28
申请号：US15812410
申请日：2017-11-14
Applicant: H. Lundbeck A/S
Inventor： Pekka Kallunki , Karina Fog , Louise Buur Vesterager , Ann-Louise Bergstrôm , Florence Sotty , David Satijn , Edward van den Brink , Paul Parren , Rik Rademaker , Tom Vink , Ibrahim John Malik , Liliana Christina Pereira Montezinho
CPC classification number: C07K16/18 , A61K39/3955 , A61K51/00 , A61K2039/505 , C07K2317/21 , C07K2317/33 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , G01N33/6896 , G01N2800/2835
Abstract: The invention relates to novel monoclonal anti-alpha-synuclein antibodies. The antibodies can be used for treating a synucleinopathy such as Parkinson's disease (including idiopathic and inherited forms of Parkinson's disease), Diffuse Lewy Body Disease (DLBD), Lewy body variant of Alzheimer's disease (LBV), Combined Alzheimer's and Parkinson disease, pure autonomic failure and multiple system atrophy.
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公开(公告)号：US20230159643A1
公开(公告)日：2023-05-25
申请号：US18057104
申请日：2022-11-18
Applicant: H. Lundbeck A/S
Inventor： Lars Christian Biilmann Rønn , Ibrahim John Malik , Jeffrey B. Stavenhagen , Soren Christensen , Jan Egebjerg , Amout Gerritsen , Edward van den Brink , Paul Parren , Rob de Jong
IPC: C07K16/28 , A61P25/28 , A61K39/395
CPC classification number: C07K16/286 , C07K16/28 , A61P25/28 , A61K39/3955 , A61K2039/505
Abstract: The present invention relates to monoclonal anti-Sortilin antibodies which have been found useful in correcting a deficient level of progranulin (PGRN). In particular, these antibodies can be used in the treatment of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS).
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