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公开(公告)号:US10800836B2
公开(公告)日:2020-10-13
申请号:US15207859
申请日:2016-07-12
Applicant: H. Lundbeck A/S
Inventor: Pekka Kallunki , Karina Fog , Louise Buur Vesterager , Ann-Louise Bergstrôm , Florence Sotty , David Satijn , Edward van den Brink , Paul Parren , Rik Rademaker , Tom Vink , Ibrahim John Malik , Liliana Christina Pereira Montezinho
Abstract: The invention relates to novel monoclonal anti-alpha-synuclein antibodies. The antibodies can be used for treating a synucleinopathy such as Parkinson's disease (including idiopathic and inherited forms of Parkinson's disease), Diffuse Lewy Body Disease (DLBD), Lewy body variant of Alzheimer's disease (LBV), Combined Alzheimer's and Parkinson disease, pure autonomic failure and multiple system atrophy.
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公开(公告)号:US20180179270A1
公开(公告)日:2018-06-28
申请号:US15812363
申请日:2017-11-14
Applicant: H. Lundbeck A/S
Inventor: Pekka Kallunki , Karina Fog , Louise Buur Vesterager , Ann-Louise Bergstrôm , Florence Sotty , David Satijn , Edward van den Brink , Paul Parren , Rik Rademaker , Tom Vink , Ibrahim John Malik , Liliana Christina Pereira Montezinho
CPC classification number: C07K16/18 , A61K39/3955 , A61K51/00 , A61K2039/505 , C07K2317/21 , C07K2317/33 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , G01N33/6896 , G01N2800/2835
Abstract: The invention relates to novel monoclonal anti-alpha-synuclein antibodies. The antibodies can be used for treating a synucleinopathy such as Parkinson's disease (including idiopathic and inherited forms of Parkinson's disease), Diffuse Lewy Body Disease (DLBD), Lewy body variant of Alzheimer's disease (LBV), Combined Alzheimer's and Parkinson disease, pure autonomic failure and multiple system atrophy.
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公开(公告)号:US11421024B2
公开(公告)日:2022-08-23
申请号:US17004447
申请日:2020-08-27
Applicant: H. Lundbeck A/S
Inventor: Pekka Kallunki , Karina Fog , Louise Buur Vesterager , Ann-Louise Bergstrôm , Florence Sotty , David Satijn , Edward Van Den Brink , Paul Parren , Rik Rademaker , Tom Vink , Ibrahim John Malik , Liliana Christina Pereira Montezinho
Abstract: The invention relates to novel monoclonal anti-alpha-synuclein antibodies. The antibodies can be used for treating a synucleinopathy such as Parkinson's disease (including idiopathic and inherited forms of Parkinson's disease), Diffuse Lewy Body Disease (DLBD), Lewy body variant of Alzheimer's disease (LBV), Combined Alzheimer's and Parkinson disease, pure autonomic failure and multiple system atrophy.
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公开(公告)号:US10358483B2
公开(公告)日:2019-07-23
申请号:US15812303
申请日:2017-11-14
Applicant: H. Lundbeck A/S
Inventor: Pekka Kallunki , Karina Fog , Louise Buur Vesterager , Ann-Louise Bergstrôm , Florence Sotty , David Satijn , Edward van den Brink , Paul Parren , Rik Rademaker , Tom Vink , Ibrahim John Malik , Liliana Christina Pereira Montezinho
IPC: C07K16/18 , A61K39/395 , A61K51/00 , G01N33/68 , A61K39/00
Abstract: The invention relates to novel monoclonal anti-alpha-synuclein antibodies. The antibodies can be used for treating a synucleinopathy such as Parkinson's disease (including idiopathic and inherited forms of Parkinson's disease), Diffuse Lewy Body Disease (DLBD), Lewy body variant of Alzheimer's disease (LBV), Combined Alzheimer's and Parkinson disease, pure autonomic failure and multiple system atrophy.
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公开(公告)号:US10358482B2
公开(公告)日:2019-07-23
申请号:US15812251
申请日:2017-11-14
Applicant: H. Lundbeck A/S
Inventor: Pekka Kallunki , Karina Fog , Louise Buur Vesterager , Ann-Louise Bergstrôm , Florence Sotty , David Satijn , Edward van den Brink , Paul Parren , Rik Rademaker , Tom Vink , Ibrahim John Malik , Liliana Christina Pereira Montezinho
IPC: C07K16/18 , A61K39/395 , A61K51/00 , G01N33/68 , A61K39/00
Abstract: The invention relates to novel monoclonal anti-alpha-synuclein antibodies. The antibodies can be used for treating a synucleinopathy such as Parkinson's disease (including idiopathic and inherited forms of Parkinson's disease), Diffuse Lewy Body Disease (DLBD), Lewy body variant of Alzheimer's disease (LBV), Combined Alzheimer's and Parkinson disease, pure autonomic failure and multiple system atrophy.
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公开(公告)号:US20180179273A1
公开(公告)日:2018-06-28
申请号:US15848999
申请日:2017-12-20
Applicant: H. Lundbeck A/S
Inventor: Karina Fog , Jeppe Falsig Pedersen
CPC classification number: C07K16/18 , A61K39/3955 , A61P25/16 , A61P25/18 , A61P25/28 , C07K2317/24 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/76
Abstract: The invention relates to a novel use of monoclonal anti-alpha-synuclein antibodies. The antibodies can be used to prevent tau aggregation and thereby treating tauopathies such as Alzheimer's disease.
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公开(公告)号:US11524995B2
公开(公告)日:2022-12-13
申请号:US16895471
申请日:2020-06-08
Applicant: H. Lundbeck A/S
Inventor: Pekka Kallunki , Karina Fog , Louise Buur Vesterager , Ann-Louise Bergström , Florence Sotty , David Satijn , Edward van den Brink , Paul Parren , Rik Rademaker , Tom Vink , Ibrahim John Malik , Liliana Christina Pereira Montezinho , Jeffrey B. Stavenhagen
Abstract: The invention relates to novel monoclonal anti-alpha-synuclein antibodies. The antibodies can be used for treating a synucleinopathy such as Parkinson's disease (including idiopathic and inherited forms of Parkinson's disease), Diffuse Lewy Body Disease (DLBD), Lewy body variant of Alzheimer's disease (LBV), Combined Alzheimer's and Parkinson disease, pure autonomic failure and multiple system atrophy.
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公开(公告)号:US10647763B2
公开(公告)日:2020-05-12
申请号:US16443187
申请日:2019-06-17
Applicant: H. Lundbeck A/S
Inventor: Pekka Kallunki , Karina Fog , Louise Buur Vesterager , Ann-Louise Bergstrôm , Florence Sotty , David Satijn , Edward Van Den Brink , Paul Parren , Rik Rademaker , Tom Vink , Ibrahim John Malik , Liliana Christina Pereira Montezinho
Abstract: The invention relates to novel monoclonal anti-alpha-synuclein antibodies. The antibodies can be used for treating a synucleinopathy such as Parkinson's disease (including idiopathic and inherited forms of Parkinson's disease), Diffuse Lewy Body Disease (DLBD), Lewy body variant of Alzheimer's disease (LBV), Combined Alzheimer's and Parkinson disease, pure autonomic failure and multiple system atrophy.
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公开(公告)号:US10364286B2
公开(公告)日:2019-07-30
申请号:US15848999
申请日:2017-12-20
Applicant: H. Lundbeck A/S
Inventor: Karina Fog , Jeppe Falsig Pedersen
IPC: A61P25/16 , A61P25/18 , A61P25/28 , C07K16/18 , A61K39/395
Abstract: The invention relates to a novel use of monoclonal anti-alpha-synuclein antibodies. The antibodies can be used to prevent tau aggregation and thereby treating tauopathies such as Alzheimer's disease.
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公开(公告)号:US10364285B2
公开(公告)日:2019-07-30
申请号:US15812363
申请日:2017-11-14
Applicant: H. Lundbeck A/S
Inventor: Pekka Kallunki , Karina Fog , Louise Buur Vesterager , Ann-Louise Bergstrôm , Florence Sotty , David Satijn , Edward van den Brink , Paul Parren , Rik Rademaker , Tom Vink , Ibrahim John Malik , Liliana Christina Pereira Montezinho
IPC: C07K16/18 , A61K39/395 , A61K51/00 , G01N33/68 , A61K39/00
Abstract: The invention relates to novel monoclonal anti-alpha-synuclein antibodies. The antibodies can be used for treating a synucleinopathy such as Parkinson's disease (including idiopathic and inherited forms of Parkinson's disease), Diffuse Lewy Body Disease (DLBD), Lewy body variant of Alzheimer's disease (LBV), Combined Alzheimer's and Parkinson disease, pure autonomic failure and multiple system atrophy.
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